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181. Explainable machine learning for predicting infections that require hospitalization in patients with systemic lupus erythematosus.
作者: Chun-Te Huang.;Min-Shian Wang.;Shang-Feng Tsai.;Yen-Ju Chen.;Yi-Hsing Chen.;Cheng-Hsu Chen.;Chieh-Liang Wu.;Wen-Nan Huang.;Hsin-Hua Chen.
来源: Rheumatology (Oxford). 2026年65卷5期
To develop and validate an explainable artificial intelligence (XAI)-based machine learning (ML) model for predicting infections requiring hospitalization in patients with systemic lupus erythematosus (SLE).
182. Scleredema of Buschke in a paediatric patient: a novel non-invasive diagnostic and monitoring approach using line-field confocal optical coherence tomography and shear wave elastography.
作者: Piotr Sobolewski.;Mateusz Koper.;Anna Dudek.;Monika Sztupecka-Rutkowska.;Anna Wasążnik-Jędras.;Małgorzata Kołos.;Irena Walecka.
来源: Rheumatology (Oxford). 2026年65卷5期 184. Diagnostic accuracy of ultrasound versus cranial MRI for giant cell arteritis: dependence on cardiovascular risk for ultrasound only.
作者: Pascal Seitz.;Susana Bucher.;Britta Maurer.;Franca Wagner.;Lukas Bütikofer.;Fabian Lötscher.;Luca Seitz.
来源: Rheumatology (Oxford). 2026年65卷5期
To compare measures of diagnostic accuracy of cranial, contrast-enhanced 3 T 2D T1-fatsat black-blood (T1fs-BB) MRI and ultrasound of the temporal arteries (TA) for suspected giant cell arteritis (GCA). To evaluate the influence of cardiovascular risk (CVR).
185. A rare JAK2 mutation associated with adult-onset Still's disease and exacerbated vaccine-induced innate immune response.
作者: Hye Kyung Lee.;Sivahari Prasad Gorantla.;Teemu Haikarainen.;Sung-Gwon Lee.;Yasemin Caf.;Nikolas von Bubnoff.;Olli Silvennoinen.;Priscilla A Furth.;Ludwig Knabl.;Lothar Hennighausen.
来源: Rheumatology (Oxford). 2026年65卷5期
Adult-onset Still's disease (AOSD) is a rare systemic autoinflammatory disorder involving immune dysregulation. The aetiology of AOSD is unknown and considered to be multigenic and possibly involving environmental triggers. Here, we report the identification of the very rare germline variant JAK2R947Q in a patient with AOSD who showed a hyperactive innate immune response after mRNA vaccination.
186. Treatment of systemic sclerosis-associated pulmonary hypertension with and without interstitial lung disease and its impact on survival: a large cohort study of the German network for systemic sclerosis.
作者: Marc Schmalzing.;Pia Moinzadeh.;Jithmi Weliwitage.;Joerg Henes.;Norbert Blank.;Gernot Keysser.;Gabriela Riemekasten.;Ulf Mueller-Ladner.;Margitta Worm.;Aaron Juche.;Alexander Kreuter.;Jan Ehrchen.;Laura Susok.;Claudia Guenther.;Gabriele Zeidler.;Ilona Jandova.;Tim Schmeiser.;Christiane Pfeiffer.;Ina Koetter.;Annette Alberding.;Joerg H W Distler.;Nicolas Hunzelmann.; .
来源: Rheumatology (Oxford). 2026年65卷5期
This study aimed to analyse survival in SS-associated pulmonary hypertension (SSc-PH) patients with or without interstitial lung disease (ILD) stratified by PH monotherapy and PH combination therapy, respectively.
187. Transcriptomic profiling of secukinumab-treated psoriatic arthritis reveals potential novel response-associated pathways.
作者: Nahdia Afiifah Abdul Jalil.;Hector Chinoy.;Meghna Jani.;Anne Barton.;Charlotte Thompson.;Paul Martin.;Nisha Nair.;James Bluett.; .
来源: Rheumatology (Oxford). 2026年65卷5期
IL-17A inhibitors are therapeutic options in PsA, but response is not universal. Evidence from other inflammatory arthritides suggests differential gene expression may predict the outcomes. This study aimed to identify transcriptomic predictive biomarkers of response in PsA patients commencing secukinumab.
188. Development of structural damage in the spine in patients with PsA: findings from a longitudinal cohort study.
作者: Fadi Kharouf.;Pankti Mehta.;Virginia Carrizo Abarza.;Shangyi Gao.;Daniel Pereira.;Ngai Chow.;Dafna D Gladman.;Vinod Chandran.;Denis Poddubnyy.
来源: Rheumatology (Oxford). 2026年65卷4期
This study aimed to examine associations between disease activity/severity markers across multiple PsA domains and structural damage development in the spine in a large longitudinal cohort.
189. A new therapeutic frontier: CD19-targeting CAR-T cell therapy in rheumatoid arthritis: a concise report.
作者: Phillip Kremer.;Isabell Haase.;Johanna Richter.;Ina Kötter.;Dominic Borie.;Boris Fehse.;Nicolaus Kröger.;Martin Krusche.;Francis Ayuk.
来源: Rheumatology (Oxford). 2026年65卷5期
Chimeric antigen receptor (CAR)-T cell therapy recently emerged as a possible new treatment option in refractory systemic autoimmune diseases (AID). With growing evidence in B cell-mediated AID, the question arises as to its potential application in difficult to treat RA. Building on positive experience in a case of overlapping seropositive RA and SSc treated with CD19 CAR-T cells at our centre, we reviewed the available evidence on the efficacy and safety of CAR-T cell therapy in RA.
192. Lung transplant outcomes in myositis, systemic sclerosis and idiopathic pulmonary fibrosis: a multicentre retrospective analysis.
作者: Angela Chang.;Navid Saleh.;Alec Yu.;Darya S Jalaledin.;Sabrina Anh-Tu Hoa.;Robert D Levy.;Jennifer M Wilson.;Charles D Poirier.;James Choi.;John Yee.;Océane Landon Cardinal.;Hyein Kim.;Kun Huang.
来源: Rheumatology (Oxford). 2026年65卷5期
To describe clinical characteristics and post-lung transplant outcomes of patients with idiopathic inflammatory myopathies (IIM), SSc and idiopathic pulmonary fibrosis (IPF).
194. Epithelial senescence predicts salivary dysfunction in Sjögren disease and glandular integrity defines residual capacity.
作者: Chiao-Feng Cheng.;Min-Shu Hsieh.;Yu-Heng Lin.;Ting-Yuan Lan.;Yi-Chieh Chen.;Jui-Hung Kao.;Yi-Min Huang.;Mei-Fang Cheng.;Hsiao-Sang Chu.;Cheng-Hsun Lu.;Chieh-Yu Shen.;Ko-Jen Li.;Tseng-Cheng Chen.;Song-Chou Hsieh.
来源: Rheumatology (Oxford). 2026年65卷4期
To investigate whether structural integrity and epithelial senescence in the submandibular gland (SMG) predict longitudinal salivary gland dysfunction in Sjögren disease (SjD).
195. Introducing a parent-centred composite disease activity score for remote monitoring in juvenile dermatomyositis.
作者: Letizia Tarantola.;Ana Isabel Rebollo-Giménez.;Alessia Sciutto.;Roberta Naddei.;Giulia Camilla Varnier.;Clarissa Pilkington.;Sue Maillard.;Adele Civino.;Elena Tsitsami.;Jaime de Inocencio.;Marija Jelusic.;Jelena Vojinovic.;Graciela Espada.;Balahan Makay.;Maria Martha Katsicas.;Polixeni Pratsidou-Gertsi.;Dragana Lazarevic.;Anand Prahalad Rao.;Alessandro Consolaro.;Angela Pistorio.;Angelo Ravelli.;Silvia Rosina.
来源: Rheumatology (Oxford). 2026年65卷5期
The objective of this study was to develop and test a composite DAS for JDM solely based on parent-reported outcomes (PROs).
196. A clinical-radiomics integrated nomogram for predicting 5-year survival in RA-associated interstitial lung disease.
作者: Hongya Liu.;Chaoyang Zhou.;Yang Zhang.;Ning Deng.;Qi Ren.;Yang Jing.;Fanxin Zeng.;Qinghua Zou.
来源: Rheumatology (Oxford). 2026年65卷5期
RA-associated interstitial lung disease (RA-ILD) shortens survival and impairs quality of life, with prognosis assessment challenging. This study aimed to predict RA-ILD patients' survival via clinical features and radiomics.
197. Association of accelerometer-measured physical activity patterns with cardiovascular diseases and mortality in people with osteoarthritis.
作者: Tianxiang Fan.;Qiyu Xie.;Jiawei Chen.;Muhui Zeng.;Shibo Chen.;Hao Yang.;Guangfeng Ruan.;Qian Yang.;Yujie Zhang.;Ye Li.;Peihua Cao.;Kim L Bennell.;Siu Ngor Fu.;David J Hunter.;Changhai Ding.;Zhaohua Zhu.
来源: Rheumatology (Oxford). 2026年65卷5期
To explore the associations between accelerometer-measured physical activity patterns and cardiovascular diseases (CVD), CVD-cause mortality and all-cause mortality in people with osteoarthritis (OA).
198. Correction: Correlations among quality of life, spinal mobility, and disease activity in early-treated axial spondyloarthritis: a single-center cross-sectional study.
作者: Tinh Khampaen.;Thanuchporn Kafaksom.;Nichapa Dechapaphapitak.;Nattakirana Tongdee.;Parawee Chevaisrakul.
来源: BMC Rheumatol. 2026年10卷1期 199. Comment on: Prevalence, distribution and associations of the scleroderma capillaroscopic patterns: new insights from the Italian SPRING-SIR registry.
作者: Hao Cheng Shen.;Valérie Leclair.;Thaisa Cotton.;Yves Troyanov.;Marie Hudson.;Geneviève Gyger.
来源: Rheumatology (Oxford). 2026年65卷4期 200. Paediatric neuro-Behçet's disease: multi-centre observational study.
作者: Zahide Ekici Tekin.;Merve Cansu Polat.;Yağmur Bayındır.;Melisa Kaçmaz.;Esra Esen.;Taner Coşkuner.;Zehra Kızıldağ.;Zuhal Karalı.;Emine Nur Sunar Yayla.;Pelin Esmeray Şenol.;Mehmet Yıldız.;Nihal Şahin.;Gülşah Kılbaş.;Nilüfer Tekgöz.;Sema Nur Taşkın.;Kübra Öztürk.;Selcan Demir.;Elif Çelikel.;Ayşenur Paç Kısaarslan.;Sara Sebnem Kilic.;Betül Sözeri.;Yelda Bilginer.;Selçuk Yüksel.;Sevcan Bakkaloğlu.;Ayşe Balat.;Erbil Ünsal.;Özgür Kasapçopur.;Seza Özen.
来源: Rheumatology (Oxford). 2026年65卷4期
Behçet's disease (BD) is a multisystemic inflammatory disease, and its neurologic involvement represents serious manifestations. This study aimed to elucidate the neurologic manifestations of BD in a large paediatric population and to describe its outcomes and prognosis.
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