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181. Impact of direct acting antivirals on hepatitis C virus-related cryoglobulinemic syndrome.
作者: Anna L Zignego.;Silvia Marri.;Laura Gragnani.
来源: Minerva Gastroenterol (Torino). 2021年67卷3期218-226页
Mixed cryoglobulinemia (MC) is a B-cell lymphoproliferative disorder largely attributable to Hepatitis C virus (HCV) infection. MC clinical manifestations are determined by systemic vasculitis of low/medium sized vessels (mixed cryoglobulinemia syndrome or cryoglobulinemic vasculitis [CV]) caused by the deposition of cryoglobulins in blood vessels.
182. Very-low-dose aspirin and surveillance colonoscopy is cost-effective in secondary prevention of colorectal cancer in individuals with advanced adenomas: network meta-analysis and cost-effectiveness analysis.
作者: Sajesh K Veettil.;Siang Tong Kew.;Kean Ghee Lim.;Pochamana Phisalprapa.;Suresh Kumar.;Yeong Yeh Lee.;Nathorn Chaiyakunapruk.
来源: BMC Gastroenterol. 2021年21卷1期130页
Individuals with advanced colorectal adenomas (ACAs) are at high risk for colorectal cancer (CRC), and it is unclear which chemopreventive agent (CPA) is safe and cost-effective for secondary prevention. We aimed to determine, firstly, the most suitable CPA using network meta-analysis (NMA) and secondly, cost-effectiveness of CPA with or without surveillance colonoscopy (SC).
183. A systematic review on pharmacokinetics, cardiovascular outcomes and safety profiles of statins in cirrhosis.
作者: Shuen Sung.;Mustafa Al-Karaghouli.;Sylvia Kalainy.;Lourdes Cabrera Garcia.;Juan G Abraldes.
来源: BMC Gastroenterol. 2021年21卷1期120页
There is increased interest in the therapeutic use of statins in cirrhosis, but preferred statin and safety outcomes are still not well known. In this systematic review we aimed to address pharmacokinetics (PK), safety, and effects on cardiovascular (CV) outcomes of statins in cirrhosis.
184. Endoscopic transmural drainage is associated with improved outcomes in disconnected pancreatic duct syndrome: a systematic review and meta-analysis.
作者: Eric Chong.;Chathura Bathiya Ratnayake.;Samantha Saikia.;Manu Nayar.;Kofi Oppong.;Jeremy J French.;John A Windsor.;Sanjay Pandanaboyana.
来源: BMC Gastroenterol. 2021年21卷1期87页
Disconnected pancreatic duct syndrome (DPDS) is a complication of acute necrotizing pancreatitis in the neck and body of the pancreas often manifesting as persistent pancreatic fluid collection (PFC) or external pancreatic fistula (EPF). This systematic review and pairwise meta-analysis aimed to review the definitions, clinical presentation, intervention, and outcomes for DPDS.
185. Risk indices predicting graft use, graft and patient survival in solid pancreas transplantation: a systematic review.
作者: Jonathan E H Ling.;Timothy Coughlan.;Kevan R Polkinghorne.;John Kanellis.
来源: BMC Gastroenterol. 2021年21卷1期80页
Risk indices such as the pancreas donor risk index (PDRI) and pre-procurement pancreas allocation suitability score (P-PASS) are utilised in solid pancreas transplantation however no review has compared all derived and validated indices in this field. We systematically reviewed all risk indices in solid pancreas transplantation to compare their predictive ability for transplant outcomes.
186. Canadian Association of Gastroenterology Clinical Practice Guideline for Immunizations in Patients With Inflammatory Bowel Disease (IBD)-Part 1: Live Vaccines.
作者: Eric I Benchimol.;Frances Tse.;Matthew W Carroll.;Jennifer C deBruyn.;Shelly A McNeil.;Anne Pham-Huy.;Cynthia H Seow.;Lisa L Barrett.;Talat Bessissow.;Nicholas Carman.;Gil Y Melmed.;Otto G Vanderkooi.;John K Marshall.;Jennifer L Jones.
来源: Gastroenterology. 2021年161卷2期669-680.e0页
Patients with inflammatory bowel disease (IBD) may be at increased risk of some vaccine-preventable diseases. The effectiveness and safety of vaccinations may be altered by immunosuppressive therapies or IBD itself. These recommendations developed by the Canadian Association of Gastroenterology and endorsed by the American Gastroenterological Association, aim to provide guidance on immunizations in adult and pediatric patients with IBD. This publication focused on live vaccines.
187. Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review and Meta-analysis.
作者: Abhiram Duvvuri.;Viveksandeep Thoguluva Chandrasekar.;Sachin Srinivasan.;Anvesh Narimiti.;ChandraShekhar Dasari.;Venkat Nutalapati.;Kevin F Kennedy.;Marco Spadaccini.;Giulio Antonelli.;Madhav Desai.;Prashanth Vennalaganti.;Divyanshoo Kohli.;Michal F Kaminski.;Alessandro Repici.;Cesare Hassan.;Prateek Sharma.
来源: Gastroenterology. 2021年160卷6期1986-1996.e3页
The risk of metachronous colorectal cancer (CRC) among patients with no adenomas, low-risk adenomas (LRAs), or high-risk adenomas (HRAs), detected at index colonoscopy, is unclear. We performed a systematic review and meta-analysis to compare incidence rates of metachronous CRC and CRC-related mortality after a baseline colonoscopy for each group.
188. Selecting End Points for Disease-Modification Trials in Inflammatory Bowel Disease: the SPIRIT Consensus From the IOIBD.
Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), are chronic and disabling disorders. Prospective disease-modification trials to prevent disease progression are eagerly awaited. However, disease progression is not clearly defined. The objective of the Selecting End PoInts foR Disease-ModIfication Trials (SPIRIT) initiative was to achieve international expert consensus on the endpoints to be used in future IBD-disease modification trials.
189. Sedation practices for routine gastrointestinal endoscopy: a systematic review of recommendations.
作者: Fahima Dossa.;Olivia Megetto.;Mafo Yakubu.;David D Q Zhang.;Nancy N Baxter.
来源: BMC Gastroenterol. 2021年21卷1期22页
Sedation is commonly used in gastrointestinal endoscopy; however, considerable variability in sedation practices has been reported. The objective of this review was to identify and synthesize existing recommendations on sedation practices for routine gastrointestinal endoscopy procedures.
190. Alterations in short-chain fatty acids and serotonin in irritable bowel syndrome: a systematic review and meta-analysis.
Short-chain fatty acids (SCFAs) and serotonin (5-hydroxytryptamine, 5-HT) may be associated with the pathogenesis of irritable bowel syndrome (IBS). There are some reports of alterations in SCFAs and 5-HT in IBS, but their results are inconsistent. We aimed to perform a meta-analysis to assess alterations in SCFAs and 5-HT in IBS patients and their potential role in the abnormal brain-gut-microbiota (BGM) axis.
191. Application of artificial intelligence in chronic liver diseases: a systematic review and meta-analysis.
作者: Pakanat Decharatanachart.;Roongruedee Chaiteerakij.;Thodsawit Tiyarattanachai.;Sombat Treeprasertsuk.
来源: BMC Gastroenterol. 2021年21卷1期10页
The gold standard for the diagnosis of liver fibrosis and nonalcoholic fatty liver disease (NAFLD) is liver biopsy. Various noninvasive modalities, e.g., ultrasonography, elastography and clinical predictive scores, have been used as alternatives to liver biopsy, with limited performance. Recently, artificial intelligence (AI) models have been developed and integrated into noninvasive diagnostic tools to improve their performance.
192. Prognostic Factors for Advanced Colorectal Neoplasia in Inflammatory Bowel Disease: Systematic Review and Meta-analysis.
作者: Anouk M Wijnands.;Michiel E de Jong.;Maurice W M D Lutgens.;Frank Hoentjen.;Sjoerd G Elias.;Bas Oldenburg.; .
来源: Gastroenterology. 2021年160卷5期1584-1598页
Patients with inflammatory bowel disease (IBD) have an increased risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to identify all prognostic factors for advanced colorectal neoplasia (aCRN, high-grade dysplasia, or CRC) in patients with IBD.
193. STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD.
作者: Dan Turner.;Amanda Ricciuto.;Ayanna Lewis.;Ferdinando D'Amico.;Jasbir Dhaliwal.;Anne M Griffiths.;Dominik Bettenworth.;William J Sandborn.;Bruce E Sands.;Walter Reinisch.;Jürgen Schölmerich.;Willem Bemelman.;Silvio Danese.;Jean Yves Mary.;David Rubin.;Jean-Frederic Colombel.;Laurent Peyrin-Biroulet.;Iris Dotan.;Maria T Abreu.;Axel Dignass.; .
来源: Gastroenterology. 2021年160卷5期1570-1583页
The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) initiative of the International Organization for the Study of Inflammatory Bowel Diseases (IOIBD) has proposed treatment targets in 2015 for adult patients with inflammatory bowel disease (IBD). We aimed to update the original STRIDE statements for incorporating treatment targets in both adult and pediatric IBD.
194. The effects of resistant starches on inflammatory bowel disease in preclinical and clinical settings: a systematic review and meta-analysis.
作者: Joshua Montroy.;Rania Berjawi.;Manoj M Lalu.;Eyal Podolsky.;Cayden Peixoto.;Levent Sahin.;Alain Stintzi.;David Mack.;Dean A Fergusson.
来源: BMC Gastroenterol. 2020年20卷1期372页
Inflammatory bowel disease (IBD) is a debilitating chronic disease with limited treatment options. Resistant starches may represent a novel treatment for IBD. However, its efficacy and safety remain unclear. Our objective was to perform a systematic review to summarize the preclinical and clinical effects of resistant starch, which may help guide future studies.
195. Adverse events of video capsule endoscopy over the past two decades: a systematic review and proportion meta-analysis.
作者: Yuan-Chen Wang.;Jun Pan.;Ya-Wei Liu.;Feng-Yuan Sun.;Yang-Yang Qian.;Xi Jiang.;Wen-Bin Zou.;Ji Xia.;Bin Jiang.;Nan Ru.;Jia-Hui Zhu.;En-Qiang Linghu.;Zhao-Shen Li.;Zhuan Liao.
来源: BMC Gastroenterol. 2020年20卷1期364页
A full spectrum of video capsule endoscopy (VCE) adverse events over the past two decades has not been evaluated. We aimed to determine pooled rates, predictors and temporal-trend of VCE adverse events over the past two decades.
196. Hyperlipasemia and Potential Pancreatic Injury Patterns in COVID-19: A Marker of Severity or Innocent Bystander?
作者: Hemant Goyal.;Sonali Sachdeva.;Abhilash Perisetti.;Rupinder Mann.;Sumant Inamdar.;Benjamin Tharian.
来源: Gastroenterology. 2021年160卷3期946-948.e2页 197. The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis.
作者: Dan Peng.;Hai-Yan Xing.;Chen Li.;Xian-Feng Wang.;Min Hou.;Bin Li.;Jian-Hong Chen.
来源: BMC Gastroenterol. 2020年20卷1期348页
Previous studies have demonstrated the benefits of thymosin alpha-1 (Tα1) in anti-virus, immunological enhancement and anti-inflammation. However, it is controversial about the efficacy and safety of entecavir (ETV) plus Tα1 combination therapy versus ETV monotherapy in cirrhotic patients with hepatitis B virus (HBV) infection.
198. Predicting Outcomes in Pediatric Crohn's Disease for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease-Ahead Program.
作者: Amanda Ricciuto.;Martine Aardoom.;Esther Orlanski-Meyer.;Dan Navon.;Nicholas Carman.;Marina Aloi.;Jiri Bronsky.;Jan Däbritz.;Marla Dubinsky.;Séamus Hussey.;Peter Lewindon.;Javier Martín De Carpi.;Víctor Manuel Navas-López.;Marina Orsi.;Frank M Ruemmele.;Richard K Russell.;Gabor Veres.;Thomas D Walters.;David C Wilson.;Thomas Kaiser.;Lissy de Ridder.;Dan Turner.;Anne M Griffiths.; .
来源: Gastroenterology. 2021年160卷1期403-436.e26页
A better understanding of prognostic factors within the heterogeneous spectrum of pediatric Crohn's disease (CD) should improve patient management and reduce complications. We aimed to identify evidence-based predictors of outcomes with the goal of optimizing individual patient management.
199. Predicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease-Ahead Program.
作者: Esther Orlanski-Meyer.;Martine Aardoom.;Amanda Ricciuto.;Dan Navon.;Nicholas Carman.;Marina Aloi.;Jiri Bronsky.;Jan Däbritz.;Marla Dubinsky.;Séamus Hussey.;Peter Lewindon.;Javier Martin De Carpi.;Víctor Manuel Navas-López.;Marina Orsi.;Frank M Ruemmele.;Richard K Russell.;Gabor Veres.;Thomas D Walters.;David C Wilson.;Thomas Kaiser.;Lissy de Ridder.;Anne Griffiths.;Dan Turner.
来源: Gastroenterology. 2021年160卷1期378-402.e22页
A better understanding of prognostic factors in ulcerative colitis (UC) could improve patient management and reduce complications. We aimed to identify evidence-based predictors for outcomes in pediatric UC, which may be used to optimize treatment algorithms.
200. Epidemiology of gastroesophageal reflux disease in Iran: a systematic review and meta-analysis.
作者: Mohammad Karimian.;Hassan Nourmohammadi.;Majid Salamati.;Mohammad Reza Hafezi Ahmadi.;Fatemeh Kazemi.;Milad Azami.
来源: BMC Gastroenterol. 2020年20卷1期297页
Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common gastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their evidence is contradictory. Therefore, the present study was conducted to investigate the epidemiology of GERD in Iran.
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