当前位置: 首页 >> 检索结果
182. A systematic review and meta-analysis: the therapeutic and preventive effect of Lactobacillus reuteri DSM 17,938 addition in children with diarrhea.
To summarize the effect of adding Lactobacillus reuteri in the treatment plan for diarrheal disease in children, and analyze the potential of probiotics in preventing the occurrence of diarrheal disease.
183. Efficacy and safety comparison of neoadjuvant chemotherapy followed by surgery and upfront surgery for treating intrahepatic cholangiocarcinoma: a systematic review and meta-analysis.
Currently, surgical resection is the most commonly performed and effective treatment for intrahepatic cholangiocarcinoma (ICC) worldwide. However, the prognosis of ICC is unsatisfactory. This study aimed to compare the efficacy and safety of neoadjuvant chemotherapy followed by surgery and upfront surgery in treating intrahepatic cholangiocarcinoma (ICC). The study also intends to explore whether chemotherapy should be introduced before surgery and which populations should be considered for neoadjuvant chemotherapy.
184. Thiols as a marker of inflammatory bowel disease activity: a systematic review.
作者: Rebeca Araujo Passos.;Priscila Ribas Farias Costa.;Claudia Feio da Maia Lima.;George Mariane Soares Santana.;Victor David.;Geisa de Jesus Santos.;Cyrla Zaltman.;Marcia Soares-Mota.;Raquel Rocha.
来源: BMC Gastroenterol. 2023年23卷1期94页
Evidence indicates that inflammation in Inflammatory Bowel Disease (IBD) is associated with increased systemic levels of reactive oxygen species. Systemic oxidative stress has been associated with reduced levels of plasma thiols. Less invasive tests capable of reflecting and predicting IBD activity are increasingly sought after. We sought to systematically review the evidence inherent in serum thiol levels as a marker of Crohn's Disease and Ulcerative Colitis activity (PROSPERO: CRD42021255521).
185. Whether the Golgi protein 73 could be a diagnostic serological marker in hepatocellular carcinoma: a meta analysis.
作者: Xu Zhang.;Li-Na Wu.;Xiao-Qing Li.;Xia Luo.;Shui-Wei Liu.;Le Zhang.;Shah Nawaz.;Li-Na Ma.;Xiang-Chun Ding.
来源: BMC Gastroenterol. 2023年23卷1期85页
The Value of Golgi protein 73 (GP73) in the diagnosis of Hepatocellular carcinoma (HCC) remains controversial, especially in its differentiation between HCC and cirrhosis. Besides, some papers showed that GP73 levels are correlated with liver fibrosis. This study conducts a meta-analysis to evaluate the value of GP73 in diagnosing HCC and differential diagnosing HCC from liver cirrhosis.
186. Effectiveness of eradication therapy for Helicobacter pylori infection in Africa: a systematic review and meta-analysis.
作者: Sintayehu Fekadu.;Hizkel Engiso.;Sisay Seyfe.;Hisashi Iizasa.;Ashebir Godebo.;Serawit Deyno.;Hironori Yoshiyama.
来源: BMC Gastroenterol. 2023年23卷1期55页
The effectiveness of Helicobacter pylori (H. pylori) eradication depends on the treatment protocol. This study investigates the H. pylori eradication rate in Africa using the best available evidence from databases.
187. The relationship between the use of metformin and the risk of pancreatic cancer in patients with diabetes: a systematic review and meta-analysis.
We aim to evaluate the relationship between the use of metformin and the risk of pancreatic cancer in type 2 diabetes patients.
188. Frequency, outcomes, and need for intervention in stricturing gastrointestinal tuberculosis: a systematic review and meta-analysis.
作者: Anuraag Jena.;Ritin Mohindra.;Kirtan Rana.;Pardhu B Neelam.;Dhuni Chand Thakur.;Harjeet Singh.;Pankaj Gupta.;Vikas Suri.;Vishal Sharma.
来源: BMC Gastroenterol. 2023年23卷1期46页
Gastrointestinal strictures impact clinical presentation in abdominal tuberculosis and are associated with significant morbidity.
189. Proteome-Wide Mendelian Randomization Identifies Causal Links Between Blood Proteins and Acute Pancreatitis.
作者: Jérôme Bourgault.;Erik Abner.;Hasanga D Manikpurage.;Natàlia Pujol-Gualdo.;Triin Laisk.; .;Émilie Gobeil.;Eloi Gagnon.;Arnaud Girard.;Patricia L Mitchell.;Sébastien Thériault.;Tõnu Esko.;Patrick Mathieu.;Benoit J Arsenault.
来源: Gastroenterology. 2023年164卷6期953-965.e3页
Acute pancreatitis (AP) is a complex disease and the leading cause of gastrointestinal disease-related hospital admissions. Few therapeutic options exist for AP prevention. Blood proteins with causal evidence may represent promising drug targets, but few have been causally linked with AP. Our objective was to identify blood proteins linked with AP by combining genome-wide association meta-analysis and proteome-wide Mendelian randomization (MR) studies.
190. Efficacy and Safety of Drugs for Gastroparesis: Systematic Review and Network Meta-analysis.
作者: Maria Rosa Ingrosso.;Michael Camilleri.;Jan Tack.;Gianluca Ianiro.;Christopher J Black.;Alexander C Ford.
来源: Gastroenterology. 2023年164卷4期642-654页
Although there have been multiple drugs tested in gastroparesis, their relative efficacy and safety are unknown. We evaluated this in a network meta-analysis of randomized controlled trials (RCTs).
191. Prevalence of frailty among patients with inflammatory bowel disease and its association with clinical outcomes: a systematic review and meta-analysis.
作者: Xiangting Huang.;Mengmeng Xiao.;Benyue Jiang.;Xiuzheng Wang.;Xiaoyu Tang.;Xiao Xu.;Ying Chen.;Shixuan Wang.;Songbo Yan.;Siyi Wang.;Jiang Wang.;Pinglan Zhang.
来源: BMC Gastroenterol. 2022年22卷1期534页
Studies have reported frailty as an independent risk factor of mortality in patients with inflammatory bowel disease (IBD). However, no systematic review and meta-analysis has been conducted to determine the relationship of frailty and IBD. We aimed to investigate the prevalence of frailty in patients with IBD and the impact of frailty on the clinical prognosis of these patients.
192. Performance and comparison of artificial intelligence and human experts in the detection and classification of colonic polyps.
作者: Ming-De Li.;Ze-Rong Huang.;Quan-Yuan Shan.;Shu-Ling Chen.;Ning Zhang.;Hang-Tong Hu.;Wei Wang.
来源: BMC Gastroenterol. 2022年22卷1期517页
The main aim of this study was to analyze the performance of different artificial intelligence (AI) models in endoscopic colonic polyp detection and classification and compare them with doctors with different experience.
193. Efficacy and safety of anti-PD-1/PD-L1 therapy in the treatment of advanced colorectal cancer: a meta-analysis.
作者: Yuegang Li.;Yuwei Du.;Chi Xue.;Pei Wu.;Nan Du.;Guolian Zhu.;Huimian Xu.;Zhi Zhu.
来源: BMC Gastroenterol. 2022年22卷1期431页
Immune checkpoint inhibitors have shown promise in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) advanced colorectal cancer (CRC) immunotherapy, and many clinical trials have been conducted.
194. Clinical and Genomic Characterization of Interval Colorectal Cancer in 3 Prospective Cohorts.
作者: Keming Yang.;Yin Cao.;Carino Gurjao.;Yang Liu.;Chuan-Guo Guo.;Chun-Han Lo.;Xiaoyu Zong.;David Drew.;Connor Geraghty.;Elizabeth Prezioso.;Matt Moore.;Craig Williams.;Tom Riley.;Melissa Saul.;Shuji Ogino.;Marios Giannakis.;Adam Bass.;Robert E Schoen.;Andrew T Chan.
来源: Gastroenterology. 2022年163卷6期1522-1530.e5页
Interval colorectal cancers (CRCs), cancers diagnosed after a screening/surveillance examination in which no cancer is detected, and before the date of next recommended examination, reflect an unprecedented challenge in CRC detection and prevention. To better understand this poorly characterized CRC variant, we examined the clinical and mutational characteristics of interval CRCs in comparison with screen detected CRCs.
195. Liver Stiffness on Magnetic Resonance Elastography and the MEFIB Index and Liver-Related Outcomes in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Individual Participants.
作者: Veeral Ajmera.;Beom Kyung Kim.;Kun Yang.;Abdul M Majzoub.;Tarek Nayfeh.;Nobuharu Tamaki.;Namiki Izumi.;Atsushi Nakajima.;Ramazan Idilman.;Mesut Gumussoy.;Digdem Kuru Oz.;Ayse Erden.;Natalie E Quach.;Xin Tu.;Xinlian Zhang.;Mazen Noureddin.;Alina M Allen.;Rohit Loomba.
来源: Gastroenterology. 2022年163卷4期1079-1089.e5页
Magnetic resonance elastography (MRE) is an accurate biomarker of liver fibrosis; however, limited data characterize its association with clinical outcomes. We conducted an individual participant data pooled meta-analysis on patients with nonalcoholic fatty liver disease to evaluate the association between liver stiffness on MRE and liver-related outcomes.
196. Diagnostic accuracy of DNA-based SDC2 methylation test in colorectal cancer screening: a meta-analysis.
作者: Lixing Wang.;Yu Liu.;Duohan Zhang.;Xiaoliang Xiong.;Tingting Hao.;Lili Zhong.;Yinlong Zhao.
来源: BMC Gastroenterol. 2022年22卷1期314页
A growing body of research suggests that methylated genes can be used as early diagnostic markers for cancer. Some studies on methylated Syndecan 2 (SDC2) have shown that it has a great diagnostic ability in colorectal cancer. This meta-analysis was aimed to estimate the diagnostic performance of methylated SDC2 as a potential novel biomarker to screen for the colorectal cancer.
197. Proactive Therapeutic Drug Monitoring Versus Conventional Management for Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis.
作者: Nghia H Nguyen.;Virginia Solitano.;Sudheer K Vuyyuru.;John K MacDonald.;Silje W Syversen.;Kristin Kaasen Jørgensen.;Eileen Crowley.;Christopher Ma.;Vipul Jairath.;Siddharth Singh.
来源: Gastroenterology. 2022年163卷4期937-949.e2页
Proactive therapeutic drug monitoring (TDM) has been proposed to improve outcomes in patients with inflammatory bowel disease (IBD) treated with tumor necrosis factor (TNF)α antagonists. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing proactive TDM with conventional management in patients with IBD.
198. Altered Mycobiota Signatures and Enriched Pathogenic Aspergillus rambellii Are Associated With Colorectal Cancer Based on Multicohort Fecal Metagenomic Analyses.
作者: Yufeng Lin.;Harry Cheuk-Hay Lau.;Yali Liu.;Xing Kang.;Yiwei Wang.;Nick Lung-Ngai Ting.;Thomas Ngai-Yeung Kwong.;Jing Han.;Weixin Liu.;Changan Liu.;Junjun She.;Sunny Hei Wong.;Joseph Jao-Yiu Sung.;Jun Yu.
来源: Gastroenterology. 2022年163卷4期908-921页
The enteric mycobiota is a major component of the human gut microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a meta-analysis to uncover the contribution of the fungal mycobiota to CRC.
199. Risk Factors for Abdominal Pain-Related Disorders of Gut-Brain Interaction in Adults and Children: A Systematic Review.
作者: Jasmine K Zia.;Adrienne Lenhart.;Pei-Lin Yang.;Margaret M Heitkemper.;Jason Baker.;Laurie Keefer.;Miguel Saps.;Callie Cuff.;Gregory Hungria.;Elizabeth J Videlock.;Lin Chang.
来源: Gastroenterology. 2022年163卷4期995-1023.e3页
Many studies have assessed risk factors of irritable bowel syndrome (IBS) and other abdominal pain-related disorders of gut-brain interaction (AP-DGBI); however, the role of these factors is unclear due to heterogeneous study designs. The aim of this systematic review was to extensively evaluate the literature and determine clinical risk and protective factors for the presence and persistence of AP-DGBI in children and adults.
200. Comparative efficacy and safety of infliximab and vedolizumab therapy in patients with inflammatory bowel disease: a systematic review and meta-analysis.
作者: Laurent Peyrin-Biroulet.;Perttu Arkkila.;Alessandro Armuzzi.;Silvio Danese.;Jordi Guardiola.;Jørgen Jahnsen.;Charles Lees.;Edouard Louis.;Milan Lukáš.;Walter Reinisch.;Xavier Roblin.;Minyoung Jang.;Han Geul Byun.;Dong-Hyeon Kim.;Sung Jeong Lee.;Raja Atreya.
来源: BMC Gastroenterol. 2022年22卷1期291页
There are limited comparative data for infliximab and vedolizumab in inflammatory bowel disease patients.
|