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2261. [Treatment strategy for adult acute lymphoblastic leukemia].2262. [Therapeutic strategy for adult acute myeloid leukemia].2263. [Cytogenetic and molecular studies on 210 patients with B-cell non-Hodgkin lymphoma using FISH and spectral karotyping].2264. [Regulation of cell cycle control in lung cancer].2265. [Growth factor induced signal transduction in lung cancer].2266. [Genetic alteration in lung cancer].2267. [Gene expression profile analysis in lung cancer].2268. [Molecular abnormalities in lung cancer].2269. [Molecular pathology of atypical adenomatous hyperplasia-adenocarcinoma sequence of the lung].2270. [Molecular mechanism of lung carcinogenesis].2271. [Association between genetic polymorphism and lung cancer risk].2272. [Influence of smoking and family history on the risk of lung cancer].2273. [Molecular diagnosis in lung cancer].2274. [Genes involved in metastasis of lung cancer].2275. [Deregulated expression of homeobox genes and cancer metastasis].2276. [Establishment of a quantitative method for detecting mixed chimerism using fluorescence-based PCR amplification of short tandem repeat markers after allogeneic hematopoietic stem cell transplantation in a Japanese population].
作者: Akiko Saito.;Seiji Ogawa.;Shinichiro Mori.;Hisashi Sakamaki.;Masahiro Kami.;Juzaburo Miyakoshi.;Yoshitomo Muto.;Tetus Hatama.;Masahiro Kawano.;Moriyoshi Kinoshita.;Shigeru Chiba.;Hisamaru Hirai.
来源: Rinsho Ketsueki. 2002年43卷5期327-32页 2277. [Chromosomal translocations revealed by long-distance polymerase chain reaction targeting genomic DNA].2278. [Gene expression analysis of AML cells using cDNA microarray].2279. [Application of new FISH techniques for cytogenetic analysis in hematological malignancies].2280. [Thyroid carcinoma: genetics, diagnosis, clinical features, and surgical treatment].
作者: Hiroshi Takami.;Yoshifumi Ikeda.;Gengo Tajima.;Shigenao Kan.;Kaori Kameyama.
来源: Nihon Geka Gakkai Zasshi. 2002年103卷6期492-4页
The genes implicated in thyroid carcinoma can be categorized as oncogenes or tumor-suppressor genes. The RET oncogene has well-established roles in the development of both medullary and papillary thyroid carcinoma (PTC). Genetic testing for the germline RET mutation is commonly performed, and prophylactic thyroidectomy is carried out at an early stage. The demonstration of a RET rearrangement in a PTC patient may be prognostic factor. TSH-R and Gs alpha are associated with the development of toxic thyroid adenoma (AFTN). The ras oncogene is implicated in the early stages of development of several tumor types. In conclusion, germline screening for RET mutations is now commonly undertaken in patients with medullary thyroid carcinoma.
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