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1. Suggested novel risk factors for Swimming-Induced Pulmonary Edema - asthma and limited open water swimming experience.
作者: Linda Kristiansson.;Claudia Seiler.;Annika Braman Eriksson.;Josefin Sundh.;Maria Hårdstedt.
来源: Chest. 2026年
Swimming-induced pulmonary edema (SIPE) has gained increasing attention in recent years. However, risk factors for SIPE remain incompletely understood, and existing data are primarily based on small-scale studies.
2. A Randomized, Placebo-Controlled, Double-Blind, Crossover Trial of Inhaled Nitric Oxide in Patients With Mild-to-Severe COPD.
作者: Sophie É Collins.;Miranda Kirby.;Benjamin M Smith.;Zahrah H Rampuri.;Desi P Fuhr.;Samira Rowland.;Andrew R Brotto.;Rhonda J Rosychuk.;Stephanie Thompson.;Jason Weatherald.;Sean van Diepen.;Michael K Stickland.; .
来源: Chest. 2026年
Patients with advanced COPD have pulmonary vascular dysfunction and destruction; thus, it is unclear whether they are responsive to selective pulmonary vasodilators.
3. Efficacy and Safety of Ensifentrine in Chinese Patients with Chronic Obstructive Pulmonary Disease: The ENHANCE-CHINA Randomized Clinical Trial.
作者: Yumin Zhou.;Charlie Chen.;Zihui Wang.;Fan Wu.;Dongbo Tian.;Zuke Xiao.;Jie Cao.;Feng Xu.;Junzhen Gao.;Juan Chen.;Liping Peng.;Yuanrong Dai.;Limin Dong.;Yi Hu.;Ting Yang.;Chuntao Liu.;Limin Wang.;Xiao Liu.;Tiebo Yang.;Guoru Yang.;Dan Zhu.;Zonghui Wei.;Wei Gu.;Pixin Ran.;Nanshan Zhong.; .
来源: Chest. 2026年
Ensifentrine, a novel phosphodiesterase 3/4 inhibitor, significantly improved lung function and reduced chronic obstructive pulmonary disease (COPD) exacerbations in previous trials in Western populations. However, efficacy and safety data on its use in participants with COPD in China remain limited.
4. Cone Beam Computed Tomography-Guided Bronchoscopy versus Computed Tomography-Guided Transthoracic Needle Biopsy for Peripheral Pulmonary Lesion Diagnosis.
作者: Pranjal Patel.;David E Ost.;Brian Shaller.;Jiwoon Chang.;Aishwarya Yenepalli.;Hee Jae Choi.;Dwayne Free.;Cyra-Yoonsun Kang.;Eric Sumner.;Carrie Cao.;Harmeet Bedi.
来源: Chest. 2026年
The identification of peripheral pulmonary lesions (PPLs) has increased significantly, either incidentally or through lung cancer screening, necessitating more biopsies to differentiate between malignant and benign etiologies. Cone beam computed tomography-guided bronchoscopic biopsy (CBCT-GB) and computed tomography-guided transthoracic needle biopsy (CT-TTNB) are commonly used for these biopsies, but their comparative diagnostic abilities have not been studied.
5. Timely antibiotics and fluid resuscitation are associated with increased discharge to home after sepsis.
作者: Hallie C Prescott.;Julien Weinstein.;Sarah Seelye.;Jason D Buxbaum.;Steven J Bernstein.;Megan Cahill.;Megan Heath.;Lama Hsaiky.;Jennifer K Horowitz.;Namita Jayaprakash.;Anurag N Malani.;Elizabeth McLaughlin.;Lakshmi Swaminathan.;Patricia J Posa.;Scott A Flanders.;Andrew M Ryan.
来源: Chest. 2026年
Sepsis is a devastating condition with frequent discharge to non-home settings such as skilled nursing facilities. Bundled payment incentive programs targeting sepsis have tried to encourage lower spending by avoiding discharge to institutional post-acute care.
6. Integrating deep learning of low-dose computed tomography with clinical data for lung cancer risk prediction.
作者: Renzo Phellan Aro.;Stephen Lam.;Matthew T Warkentin.;Geoffrey Liu.;Brenda Diergaarde.;David O Wilson.;Jian-Min Yuan.;Hamad Al-Sawaihey.;Kiera Murison.;Elham Khodayari Moez.;Yonathan Brhane.;Rafael Meza.;Renelle Myers.;Rayjean J Hung.
来源: Chest. 2026年
Low-dose computed tomography (LDCT) screening reduces lung cancer mortality, the leading cause of cancer deaths globally. Segmentation-free deep learning (DL) models such as Sybil can improve screening efficiency but require extensive validation and possible improvement.
10. Antimicrobial Treatment of Mild Mycobacterium avium Complex-Pulmonary Disease Predicted to Increase Survival and Quality Adjusted Life Years: A Microsimulation Decision Analysis Model.
作者: Omri A Arbiv.;Gemma Postill.;Yunjoo Im.;Byung Woo Jhun.;Petros Pechlivanoglou.;Sarah K Brode.;Ahmed M Bayoumi.;Theodore K Marras.
来源: Chest. 2026年
Mycobacterium avium complex-pulmonary disease (MAC-PD) can lead to chronic lung disease, which can necessitate intensive antimicrobial therapy. In patients with mild MAC-PD, there is uncertainty in whether guideline-based antimicrobial treatment should be used as compared to watchful waiting.
11. OSA is associated with enhanced coronary collateral circulation and reduced myocardial injury during acute coronary syndromes.
作者: Krish Dodani.;Albina Aldomà.;Adriano Targa.;Manuel Sánchez-de-la-Torre.;Alicia Sánchez-de-la-Torre.;Lucía Pinilla.;Jorge Abad.;Olga Mínguez.;Lydia Pascual.;Dolores Martínez.;Rafaela Vaca.;Ivan Juez-Garcia.;Ferran Barbé.;Ivan Benitez.
来源: Chest. 2026年
Some evidence suggests that obstructive sleep apnea (OSA) may attenuate myocardial injury and reduce infarct severity during acute coronary syndromes (ACS), potentially through stimulation of coronary collateral circulation (CCC). However, the relationship between OSA and collateral development, and their combined impact on ACS event severity, remains unclear.
12. Clinical and cost-effectiveness of pulmonary rehabilitation for people with post-tuberculosis lung disease in Uganda: a randomised controlled trial.
作者: Winceslaus Katagira.;Mark W Orme.;Richard Kasiita.;Jesse A Matheson.;Matthew Richardson.;Andy Barton.;Jalia Nanyonga.;Michael C Steiner.;Bruce Kirenga.;Sally J Singh.
来源: Chest. 2026年
Background Post-tuberculosis lung disease (PTLD) causes significant disability in TB survivors. Pulmonary rehabilitation (PR) may offer effective disease management but lacks high-quality evidence in this underrepresented population.
13. Win Ratio Analysis to Clarify Clinical Benefits: A Post Hoc Analysis of Phase 3 BOREAS and NOTUS.
作者: Sanjay Ramakrishnan.;Nayia Petousi.;Jessica Bon.;Ian D Pavord.;Surya P Bhatt.;Klaus F Rabe.;Wenying Deng.;Changming Xia.;Jigna Heble.;Mena Soliman.;Simon Couillard.
来源: Chest. 2026年 14. Evaluating the Association Between Patient Priorities and ICU Care Delivery in Adults Receiving Mechanical Ventilation.
作者: Kara A Donovan.;Madison Polley.;Geralyn Palmer.;Bret M Hanlon.;Lily N Stalter.;Helen K Donnelly.;Richard G Wunderink.;Catherine A Gao.;Jacqueline M Kruser.; .
来源: Chest. 2026年
Understanding how intensive care unit (ICU) treatments align with a patient's priorities is crucial to evaluating and improving critical care. Yet, measuring this alignment is challenging because patient priorities evolve over time and are not systematically documented in electronic health records (EHR).
15. Demographic and physiologic differences between fibrotic and non-fibrotic CT subtypes of sarcoidosis.
作者: Ruchi Yadav.;Wren L Lippitt.;Kum Ju Chae.;Jared Rieck.;Nichole E Carlson.;Shu-Yi Liao.;Margaret M Mroz.;Briana Barkes.;Stephen M Humphries.;Andrea Oh.;Hye Jeon Hwang.;Katherine Parker.;Andrea I Fuentealba.;Thomas McLaren.;Cristina Marrocchio.;Tasha E Fingerlin.;Daniel A Culver.;David A Lynch.;Lisa A Maier.
来源: Chest. 2026年
One approach to categorizing patients using chest computed tomography (CT) imaging manifestations of pulmonary sarcoidosis is into three classifications: fibrotic, non-fibrotic, or no parenchymal abnormality. We aimed to evaluate the relationships between these imaging subtypes and demographic and physiologic variables in a large group of sarcoidosis patients with chest CT.
16. The Impact of Weight Loss on the Physiological Endotypes Associated With OSA.
作者: Caroline J Beatty.;Ai-Ming Wong.;Shane A Landry.;Luke D J Thomson.;Jinny Collet.;Veronica Odeke.;Simon A Joosten.;Julie Playfair.;Atul Malhotra.;Kirk Kee.;Matthew T Naughton.;Kate Sutherland.;Peter A Cistulli.;Sanjay R Patel.;Wendy A Brown.;Garun S Hamilton.;Bradley A Edwards.
来源: Chest. 2026年
Weight loss improves upper airway collapsibility in people with OSA. However, it is unclear how weight loss affects the other physiological traits (ie, endotypes) associated with OSA (loop gain, arousal threshold, and muscle compensation).
17. Three-Year Outcomes of Proximal Hypoglossal Nerve Stimulation in OSA.
作者: Alan R Schwartz.;Ofer Jacobowitz.;Samuel A Mickelson.;Mitchell B Miller.;Arie Oliven.;Victor Certal.;Martin L Hopp.;David H Winslow.;Tod C Huntley.;Nathan E Nachlas.;Luu V Pham.;David W Eisele.;M Boyd Gillespie.;Brian H Weeks.;Eric G Lovett.;John Shen.;Atul Malhotra.;Joachim T Maurer.
来源: Chest. 2026年
Targeted proximal hypoglossal nerve stimulation (THN, pHGNS) improved sleep-disordered breathing, sleep architecture, and quality of life (QOL) with a favorable safety profile over 1 year in the THN3 randomized, controlled trial. Herein, THN3 pHGNS 3-year safety and efficacy are profiled with reference to distal HGNS (dHGNS) from the STAR trial.
18. Reducing Inhaler Waste and Costs Through Sustainable Interventions.
作者: Marianne Laguë.;Isabelle Giroux.;Alexandre Sanctuaire.;Julie Racicot.;Cassiopée Gagnon-Paradis.;François Maltais.;Andréanne Côté.;Krystelle Godbout.
来源: Chest. 2026年169卷2期326-328页 19. Daily Physical Activity in Pulmonary Arterial Hypertension: Insights From a Multicenter Longitudinal Trial Using Accelerometry.
作者: Jasleen Minhas.;Haochang Shou.;Nadine Al-Naamani.;Rui Feng.;Roham Zamanian.;Todd Bull.;Murali Chakinala.;Anna Hemnes.;Jude Moutchia.;Stephen C Mathai.;Susan Ellenberg.;Corey Ventetuolo.;Steven M Kawut.
来源: Chest. 2026年
Pulmonary arterial hypertension (PAH) is a progressive disease associated with high morbidity and mortality. Traditional assessments such as the 6-minute walk distance (6MWD) may not adequately capture daily physical activity or patient experience in real-world settings.
20. Outcomes of Severe Mpox Admitted to ICUs at Two Large New York City Health Systems, 2022-2024.
作者: Anthony J Lo Piccolo.;Shane Antoinette Arante.;Justin Chan.;Kathryn Jano.;Madeline A DiLorenzo.;Melissa Achenbaum.;Regan Britt.;David Butler.;Radu Postelnicu.;Erin McGuire.;Vikramjit Mukherjee.
来源: Chest. 2026年 |