1. In arterial hypertension, renal denervation vs. a sham procedure reduces ambulatory and office BP at ≤6 mo.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Nephrology: [Formula: see text].
2. In adults with obesity and knee OA, adding weekly semaglutide to diet and activity counseling reduced weight and knee pain at 68 wk.
GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text] Rheumatology: [Formula: see text].
3. Effects of Noise and Public Setting on Blood Pressure Readings : A Randomized Crossover Trial.
作者: Junichi Ishigami.;Hairong Liu.;Di Zhao.;Ahmed Sabit.;Chathurangi H Pathiravasan.;Jeanne Charleston.;Edgar R Miller.;Kunihiro Matsushita.;Lawrence J Appel.;Tammy M Brady.
来源: Ann Intern Med. 2025年178卷2期149-156页
Guidelines emphasize quiet settings for blood pressure (BP) measurement.
5. In asymptomatic severe AS, early surgery vs. conservative therapy reduced a composite of death, MI, stroke, or HF hospitalization at 63 mo.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
6. In insulin-naive T2D, weekly efsitora was noninferior to daily degludec for reducing HbA1c at 52 wk.
GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text].
7. The Effect of the "Safety in Dementia" Online Tool to Assist Decision Making for Caregivers of Persons With Dementia and Access to Firearms : A Randomized Trial.
作者: Marian E Betz.;Jennifer Portz.;Christopher Knoepke.;Megan L Ranney.;Stacy M Fischer.;Ryan A Peterson.;Rachel L Johnson.;Faris Omeragic.;Mirella Castaneda.;Emily Greenway.;Daniel Matlock.
来源: Ann Intern Med. 2024年177卷12期1630-1640页
Caregivers face challenges (including competing desires to prevent injury, respect autonomy, and avoid conflict) when addressing firearm access by community-dwelling persons with Alzheimer disease and related dementias (ADRD).
8. Diabetes Risk Factors in People With HIV Receiving Pitavastatin Versus Placebo for Cardiovascular Disease Prevention : A Randomized Trial.
作者: Kathleen V Fitch.;Markella V Zanni.;Jennifer Manne-Goehler.;Marissa R Diggs.;Arijeet K Gattu.;Judith S Currier.;Gerald S Bloomfield.;Chiu-Bin Hsiao.;Samir K Gupta.;Judith A Aberg.;Carlos D Malvestutto.;Carl J Fichtenbaum.;Michael T Lu.;Pamela S Douglas.;Heather J Ribaudo.;Steven K Grinspoon.
来源: Ann Intern Med. 2024年177卷11期1449-1461页
REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) led to new guidelines for statin use among people with HIV (PWH) with low to moderate risk for atherosclerotic cardiovascular disease (ASCVD). Little is known about the natural history of diabetes mellitus (DM) or mechanisms contributing to statin effects on DM among this population.
9. Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia : A Target Trial Emulation Using MINT Trial Data.
作者: Gerard T Portela.;Jeffrey L Carson.;Sonja A Swanson.;John H Alexander.;Paul C Hébert.;Shaun G Goodman.;Philippe Gabriel Steg.;Marnie Bertolet.;Jordan B Strom.;Dean A Fergusson.;Tabassome Simon.;Harvey D White.;Howard A Cooper.;J Dawn Abbott.;Sunil V Rao.;Bernard R Chaitman.;Christopher B Fordyce.;Renato D Lopes.;Benoit Daneault.;Maria M Brooks.; .
来源: Ann Intern Med. 2024年177卷11期1489-1498页
The optimal hemoglobin threshold to guide red blood cell (RBC) transfusion for patients with acute myocardial infarction (MI) and anemia is uncertain.
10. Effectiveness of Integrating Suicide Care in Primary Care : Secondary Analysis of a Stepped-Wedge, Cluster Randomized Implementation Trial.
作者: Julie Angerhofer Richards.;Maricela Cruz.;Christine Stewart.;Amy K Lee.;Taylor C Ryan.;Brian K Ahmedani.;Gregory E Simon.
来源: Ann Intern Med. 2024年177卷11期1471-1481页
Primary care encounters are common among patients at risk for suicide.
11. Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial.
作者: Emily N C Manoogian.;Michael J Wilkinson.;Monica O'Neal.;Kyla Laing.;Justina Nguyen.;David Van.;Ashley Rosander.;Aryana Pazargadi.;Nikko R Gutierrez.;Jason G Fleischer.;Shahrokh Golshan.;Satchidananda Panda.;Pam R Taub.
来源: Ann Intern Med. 2024年177卷11期1462-1470页
Time-restricted eating (TRE), limiting daily dietary intake to a consistent 8 to 10 hours without mandating calorie reduction, may provide cardiometabolic benefits.
12. Long-Term Effects of Individualized Acupuncture for Chronic Neck Pain : A Randomized Controlled Trial.
作者: Ling Zhao.;Mingsheng Sun.;Zihan Yin.;Jin Cui.;Ruihui Wang.;Laixi Ji.;Guoyan Geng.;Jiao Chen.;Dingjun Cai.;Qi Liu.;Hui Zheng.;Fanrong Liang.
来源: Ann Intern Med. 2024年177卷10期1330-1338页
Long-term effects of individualized acupuncture in persons with chronic neck pain (CNP) remain unknown.
13. Endoscopic Ultrasound-Guided Rendezvous Technique Versus Precut Sphincterotomy as Salvage Technique in Patients With Benign Biliary Disease and Difficult Biliary Cannulation : A Randomized Controlled Trial.
作者: Arup Choudhury.;Jayanta Samanta.;Gaurav Muktesh.;Jahnvi Dhar.;Antriksh Kumar.;Jimil Shah.;Marco Spadaccini.;Pankaj Gupta.;Alessandro Fugazza.;Vikas Gupta.;Thakur Deen Yadav.;Rakesh Kochhar.;Cesare Hassan.;Alessandro Repici.;Antonio Facciorusso.
来源: Ann Intern Med. 2024年177卷10期1361-1369页
The standard salvage technique used for difficult bile duct cannulation is precut sphincterotomy, whereas endoscopic ultrasound-guided rendezvous technique (EUS-RV) is a relatively newer method. Prospective comparative data between these 2 techniques as salvage for biliary access in patients with benign biliary disease and difficult bile duct cannulation is lacking.
14. Efficacy of a Therapeutic Pelvic Yoga Program Versus a Physical Conditioning Program on Urinary Incontinence in Women : A Randomized Trial.
作者: Alison J Huang.;Margaret Chesney.;Michael Schembri.;Harini Raghunathan.;Eric Vittinghoff.;Wendy Berry Mendes.;Sarah Pawlowsky.;Leslee L Subak.
来源: Ann Intern Med. 2024年177卷10期1339-1349页
Pelvic floor yoga has been recommended as a complementary treatment strategy for urinary incontinence (UI) in women, but evidence of its efficacy is lacking.
15. Pain Reduction With Oral Methotrexate in Knee Osteoarthritis : A Randomized, Placebo-Controlled Clinical Trial.
作者: Sarah R Kingsbury.;Puvan Tharmanathan.;Ada Keding.;Fiona E Watt.;David L Scott.;Edward Roddy.;Fraser Birrell.;Nigel K Arden.;Mike Bowes.;Catherine Arundel.;Michelle Watson.;Sarah J Ronaldson.;Catherine Hewitt.;Michael Doherty.;Robert J Moots.;Terence W O'Neill.;Michael Green.;Gulam Patel.;Toby Garrood.;Christopher J Edwards.;Phil J Walmsley.;Tom Sheeran.;David J Torgerson.;Philip G Conaghan.
来源: Ann Intern Med. 2024年177卷9期1145-1156页
Treatments for osteoarthritis (OA) are limited. Previous small studies suggest that the antirheumatic drug methotrexate may be a potential treatment for OA pain.
16. Effect of Acupuncture for Methadone Reduction : A Randomized Clinical Trial.
作者: Liming Lu.;Chen Chen.;Yiming Chen.;Yu Dong.;Rouhao Chen.;Xiaojing Wei.;Chenyang Tao.;Cui Li.;Yuting Wang.;Baochao Fan.;Xiaorong Tang.;Shichao Xu.;Zhiqiu He.;Guodong Mo.;Yiliang Liu.;Hong Gu.;Xiang Li.;Fang Cao.;Hongxia Xu.;Yuqing Zhang.;Guowei Li.;Xinxia Liu.;Jingchun Zeng.;Chunzhi Tang.;Nenggui Xu.
来源: Ann Intern Med. 2024年177卷8期1039-1047页
Methadone maintenance treatment (MMT) is effective for managing opioid use disorder, but adverse effects mean that optimal therapy occurs with the lowest dose that controls opioid craving.
17. Effect of Acupuncture on Neurogenic Claudication Among Patients With Degenerative Lumbar Spinal Stenosis : A Randomized Clinical Trial.
作者: Lili Zhu.;Yuanjie Sun.;Jing Kang.;Jun Liang.;Tongsheng Su.;Wenbin Fu.;Wei Zhang.;Rongshui Dai.;Yan Hou.;Hong Zhao.;Weina Peng.;Weiming Wang.;Jing Zhou.;Ruimin Jiao.;Biyun Sun.;Yan Yan.;Yan Liu.;Zhishun Liu.
来源: Ann Intern Med. 2024年177卷8期1048-1057页
Acupuncture may improve degenerative lumbar spinal stenosis (DLSS), but evidence is insufficient.
18. Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men : A Randomized Controlled Trial.
作者: Yanxiao Gao.;Yuewei Zhan.;Yinghui Sun.;Weiran Zheng.;Weijie Zhang.;Leiwen Fu.;Zhihui Guo.;Yi-Fan Lin.;Yuwei Li.;Lingling Zheng.;Yiqiang Zhan.;Zhiqiang Zhu.;Junyi Duan.;Guanghui Zhang.;Tao Huang.;Bin Su.;Maohe Yu.;Guohui Wu.;Lin Ouyang.;Jin Zhao.;Guanghui Wang.;Yepeng Zhou.;Han-Zhu Qian.;Thomas Fitzpatrick.;Sten H Vermund.;Huachun Zou.
来源: Ann Intern Med. 2024年177卷6期719-728页
Observational studies suggest that voluntary medical male circumcision (VMMC) may lower HIV risk among men who have sex with men (MSM). A randomized controlled trial (RCT) is needed to confirm this.
19. Extracorporeal Shock-Wave Lithotripsy and Endoscopy for the Treatment of Pain in Chronic Pancreatitis : A Sham-Controlled, Randomized Trial.
作者: Rupjyoti Talukdar.;Søren S Olesen.;Misbah Unnisa.;Akshay Bedarkar.;Subhaleena Sarkar.;Manu Tandan.;Nitin Jagtap.;Santosh Darisetty.;Sekhramantri Kiran.;Vinod Koppoju.;Sundeep Lakhtakia.;Mohan Ramchandani.;Rakesh Kalapala.;Rajesh Gupta.;Vikesh K Singh.;Guduru Venkat Rao.;Duvvur Nageshwar Reddy.;Asbjørn M Drewes.
来源: Ann Intern Med. 2024年177卷6期749-758页
No randomized controlled trials have substantiated endoscopic decompression of the pancreatic duct in patients with painful chronic pancreatitis.
20. Effect of Isocaloric, Time-Restricted Eating on Body Weight in Adults With Obesity : A Randomized Controlled Trial.
作者: Nisa M Maruthur.;Scott J Pilla.;Karen White.;Beiwen Wu.;May Thu Thu Maw.;Daisy Duan.;Ruth-Alma Turkson-Ocran.;Di Zhao.;Jeanne Charleston.;Courtney M Peterson.;Ryan J Dougherty.;Jennifer A Schrack.;Lawrence J Appel.;Eliseo Guallar.;Jeanne M Clark.
来源: Ann Intern Med. 2024年177卷5期549-558页
Time-restricted eating (TRE) lowers body weight in many studies. Whether TRE induces weight loss independent of reductions in calorie intake, as seen in rodent studies, is unknown.
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