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141. Development of a liver stiffness measurement-based nomogram model to identify early CKD risk in patients with MAFLD.
作者: Dejin Huang.;Xiaoxuan Ma.;Qingchen Gao.;Xiaolong Shen.;Tongtong Yu.;Rongqi Wang.
来源: BMC Gastroenterol. 2026年26卷1期
To identify independent relevant factors for chronic kidney disease (CKD) in patients with metabolic dysfunction-associated fatty liver disease (MAFLD) and to develop and validate a nomogram-based risk diagnostic model for MAFLD-CKD incorporating liver stiffness measurement (LSM).
142. Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.
作者: Jean-Frédéric Colombel.;Damian Garcia Olmo.;Szu-Ta Chen.;Zuzana Serclova.;David A Schwartz.;Steven D Wexner.;Julian Panés.;Chunyuan Wu.;Barbara Zhang.;Michael Song.;Caroline McKay.;Pradeep Nazarey.;Ekaterina Wright.;Laura Raffals.;Phillip Fleshner.
来源: Gastroenterology. 2026年
The ADMIRE CD trial demonstrated the efficacy and safety of darvadstrocel in patients with complex perianal fistulas from Europe and Israel. The efficacy and safety of darvadstrocel in an expanded patient population was investigated.
143. Revealing the Antagonistic Interactions of Faecalibacterium prausnitzii and Bacteroides fragilis in Colorectal Cancer.
作者: Cheng Kong.;Yutao Jin.;Fanying Guo.;Yongzhi Yang.;Guang Liu.;Ziying Chen.;Jinming Li.;Qinying Wang.;Yanlei Ma.
来源: Gastroenterology. 2026年
Maladaptation of host-microbe metabolic interactions plays a crucial role in development of colorectal cancer (CRC). However, remains a lack of comprehensive studies using multi-omics analysis to illustrate host-microbe metabolic interactions in CRC.
144. A Gut-Restricted Liver X Receptor Agonist Ameliorates Liver Injury in Experimental Short Bowel Syndrome.
作者: Ayoung Kim.;Daniel M Alligood.;Lingaiah Maram.;Hannah M Phelps.;Michael Cameron.;Jacob T DeRousse.;Jichang Han.;Taylor J Dunning.;Rachel L Mintz.;Alex Park.;Daniel D Lee.;Deanna L Davis.;Christopher G Huckstep.;Rachael L Field.;Lamees Hegazy.;Bernd H Zinselmeyer.;Jonathan R Brestoff.;Colin A Martin.;Brad W Warner.;Bahaa Elgendy.;Gwendalyn J Randolph.
来源: Gastroenterology. 2026年
Short bowel syndrome (SBS) arises from the surgical removal of extensive portions of the small intestine and is associated with high morbidity, including intestinal failure-associated liver disease (IFALD). Earlier studies revealed that orally administered systemic liver X receptor (LXR) agonist suppresses IFALD in mice and implicated intestinally derived high-density lipoprotein (HDL) in liver protection. Here we aimed to move away from the use of systemic LXR agonists because they have failed in clinical trials due to hepatic steatosis and hyperlipidemia, to determine if a gut-restricted LXR agonist could provide hepatoprotection in SBS.
145. Gastric Peroral Endoscopic Pyloromyotomy (G-POEM) Is Effective in the Treatment of Diabetic Gastroparesis: A Randomized, Double-Blinded, Sham-Controlled Trial.
作者: Melina Svraka Hansen.;Palle Beck Miliam.;Morten Damgaard.;Ismail Gögenur.;Christian Stevns Hansen.;John Gásdal Karstensen.; .
来源: Gastroenterology. 2026年 146. Development and validation of a deep learning radiomics model based on ultrasound and clinical features to predict prognosis in elderly patients with advanced pancreatic cancer after HIFU therapy.
作者: Yumei Liu.;Yongshuo Ji.;Junqiu Zhu.;Linglin Zhu.;Yanfei Zhu.;Hong Zhao.;Zhijun Bao.
来源: BMC Gastroenterol. 2026年 147. Tacrolimus therapy for ulcerative colitis: a retrospective study of factors associated with inducing and maintaining remission.
作者: Ayumi Ito.;Shun Murasugi.;Miki Koroku.;Maria Yonezawa.;Teppei Omori.;Shinichi Nakamura.;Katsutoshi Tokushige.;Yousuke Nakai.
来源: BMC Gastroenterol. 2026年 148. Metabolic factors associated with colorectal neoplasms: a single center retrospective cross-sectional analysis of colonoscopy patients.
作者: Junya Arai.;Hiroaki Fujiwara.;Tomonori Aoki.;Ryota Niikura.;Sozaburo Ihara.;Nobumi Suzuki.;Yosuke Tsuji.;Yoku Hayakawa.;Masato Kasuga.;Mitsuhiro Fujishiro.
来源: BMC Gastroenterol. 2026年 149. Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn's disease.
作者: Mengting Huang.;Shuo Huang.;Qinyue Luo.;Yuting Zheng.;Hanting Li.;Ping Han.;Liangru Zhu.;Heshui Shi.
来源: BMC Gastroenterol. 2026年
Central nervous system involvement has been implicated in the pathophysiology of Crohn's disease (CD). This study aimed to develop a predictive model integrating choroid plexus (CP) morphology derived from brain MRI with clinical and psychological factors to forecast treatment outcomes following anti-tumor necrosis factor-alpha (anti-TNF-ɑ) therapy in CD.
150. The role of GP73 in predicting overall survival and chemotherapy response in locally advanced gastric cancer: a retrospective cohort study.
作者: Altay Aliyev.;Arturan Ibrahimli.;Johnn Henry Herrera Kok.;Elgun Samadov.;Farida Aghayarli.;Iqbal Babazade.;Parvana Asgarova.;Adila Adilli.;Akbar Hajiyev.;Jamal Musayev.
来源: BMC Gastroenterol. 2026年26卷1期
Gastric cancer (GC) is a leading cause of cancer-related mortality globally, with a 5-year survival rate remaining below 50% despite advancements in treatment. The standard care for locally advanced GC includes curative gastrectomy combined with perioperative chemotherapy. Different factors may influence chemotherapy responses, underscoring the need for biomarkers to tailor treatment. GP73, a Golgi-associated protein, has been implicated in cancer progression and prognosis, though its role in GC remains poorly understood. This study aimed to evaluate the association between pretreatment GP73 expression and overall survival (OS) and chemotherapy response in locally advanced GC patients.
151. Profile and diagnostic value of N6-methyladenosine-related mRNA regulators in colorectal adenoma and colorectal cancer.
作者: Wei Wang.;Xiaohui Zhang.;Min Wang.;Li Wang.;Shiqing Qian.;Wenli Cheng.;Fang Xu.;Shaopeng Ding.;Yuting Zhu.;Guoqing Jin.;Wanshui Yang.;Anla Hu.;Qihong Zhao.
来源: BMC Gastroenterol. 2026年 153. Cardiovascular Outcomes Following Major Gastrointestinal Bleeding in Patients with Pre-existing Cardiovascular Disease: The INTERBLEED International Prospective Cohort Study.
作者: Nauzer Forbes.;John W Eikelboom.;Qilong Yi.;Paul Moayyedi.;Marco Alings.;Shrikant I Bangdiwala.;Alan N Barkun.;Federico Cassella.;Irfan Duzen.;Leah Hamilton.;Mustafa Kilickap.;Paul Kruger.;Yan Liang.;Jose C Nicolau.;Rafael Belo Nunes.;Martin O'Donnell.;Alejandro Rey.;Shofiqul Islam.;Thomas Vanassche.;Peter Verhamme.;Cynthia Wu.;Li Zhao.;Jun Zhu.;Jacqueline Bosch.
来源: Gastroenterology. 2026年
Gastrointestinal bleeding (GIB) is common in patients with cardiovascular (CV) disease, but a complete understanding of subsequent outcomes is unknown. We assessed outcomes after GIB in patients with CV disease.
156. Epidemiologic transition of biliary tract cancers in an endemic region of Korea: insights from a regional cancer center cohort.
Biliary tract cancers (BTCs) in East Asia have traditionally been linked to inflammation-related etiologies. However, metabolic risk factors are increasingly contributing to BTC development. Temporal trends in BTC epidemiology remain underexplored in the Korean population. This study aimed to review 13-year trends in BTCs, focusing on metabolic and inflammatory comorbidities, in a southeastern Korean cancer center historically characterized by a high incidence of inflammation-related BTCs.
158. Comparison of the efficacy of transarterial chemoembolization combined with radiofrequency ablation or sintilimab and bevacizumab for unresectable hepatocellular carcinoma.160. Creatinine-to-body weight ratio as an independent predictor of hepatic steatosis severity in metabolic dysfunction-associated steatotic liver disease: a cross-sectional study.
作者: Xiaoning Sun.;Xiaozhong Wang.;Ayesha Younas.;Shuanghu Wang.;Muhammad Sohail.;Jiaojian Lv.;Zuxiu Huang.;Yunxiao Liu.
来源: BMC Gastroenterol. 2026年 |