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89. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial.
作者: Feng Pan.;Yuanyuan Wang.;Yuan Z Lim.;Donna M Urquhart.;Mahnuma Mahfuz Estee.;Anita E Wluka.;Rory Wolfe.;Flavia M Cicuttini.
来源: JAMA. 2025年
Preclinical and preliminary human evidence suggests that metformin, a first-line treatment for type 2 diabetes, reduces inflammation, preserves cartilage, and improves knee pain in knee osteoarthritis.
91. Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US.
Widespread childhood vaccination has eliminated many infectious diseases in the US. However, vaccination rates are declining, and there are ongoing policy debates to reduce the childhood vaccine schedule, which may risk reemergence of previously eliminated infectious diseases.
96. Trends in Mental Health Diagnoses Among Publicly Insured Children.
Children living in poverty are at increased risk of mental health and neurodevelopmental disorders. Little is known about the trends in diagnoses of these disorders among children enrolled in public insurance programs, such as Medicaid, which insure more than 1 in 3 US children.
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