702. Negative Pressure Dressings to Prevent Surgical Site Infection After Emergency Laparotomy: The SUNRRISE Randomized Clinical Trial.
作者: .;Kristy Atherton.;James Brown.;Hamish Clouston.;Pete Coe.;Rui Duarte.;Nagendra N Dudi-Venkata.;Sarah Duff.;Natasha Egoroff.;Rebecca Fish.;James Glasbey.;Natalie Ives.;Manjinder Kaur.;Laura Magill.;Samir Mehta.;Thomas Pinkney.;Peter Pockney.;Toby Richards.;Tarik Sammour.;Hema Sekhar.;Yash Sinha.;Martyn Stott.;Richard Wilkin.
来源: JAMA. 2025年333卷10期853-863页
Patients undergoing unplanned abdominal surgical procedures are at increased risk of surgical site infection (SSI). It is not known if incisional negative pressure wound therapy (iNPWT) can reduce SSI rates in this setting.
704. Essential Thrombocythemia: A Review.
作者: Ayalew Tefferi.;Naseema Gangat.;Giuseppe Gaetano Loscocco.;Paola Guglielmelli.;Natasha Szuber.;Animesh Pardanani.;Attilio Orazi.;Tiziano Barbui.;Alessandro Maria Vannucchi.
来源: JAMA. 2025年333卷8期701-714页
Essential thrombocythemia, a clonal myeloproliferative neoplasm with excessive platelet production, is associated with an increased risk of thrombosis and bleeding. The annual incidence rate of essential thrombocythemia in the US is 1.5/100 000 persons.
719. Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer: The TaLaR Randomized Clinical Trial.
作者: Ziwei Zeng.;Shuangling Luo.;Hong Zhang.;Miao Wu.;Dan Ma.;Quan Wang.;Ming Xie.;Qing Xu.;Jun Ouyang.;Yi Xiao.;Yongchun Song.;Bo Feng.;Qingwen Xu.;Yanan Wang.;Yi Zhang.;Lishuo Shi.;Li Ling.;Xingwei Zhang.;Liang Huang.;Zuli Yang.;Junsheng Peng.;Xiaojian Wu.;Donglin Ren.;Meijin Huang.;Ping Lan.;Jianping Wang.;Weidong Tong.;Mingyang Ren.;Huashan Liu.;Liang Kang.; .
来源: JAMA. 2025年333卷9期774-783页
Previous studies have demonstrated the advantages of short-term histopathological outcomes and complications associated with transanal total mesorectal excision (TME) compared with laparoscopic TME. However, the long-term oncological outcomes of transanal TME remain ambiguous. This study aims to compare 3-year disease-free survival of transanal TME with laparoscopic TME.
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