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561. Global, regional, and national burden of NAFLD in adults aged 20-49 years (1990-2021): a comprehensive analysis of trends, decomposition, and health inequality.
Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern, particularly among adults aged 20-49 years. However, comprehensive assessments of its burden in this demographic remain limited.
562. The prevalence and associated factors of autoimmune gastritis: single-center, hospital-based prospective study in China.
Autoimmune gastritis (AIG) is a chronic immune-mediated disease characterized by anti-parietal cell antibody (PCA) and corpus-predominant atrophy. However, epidemiological data on AIG remain limited in China where the prevalence of Helicobacter pylori (H. pylori) is high. This study aimed to estimate the prevalence and associated factors of AIG in a hospital-based population.
563. The effects of family-based Helicobacter pylori infection control and management strategies in Southwest China households: a two-year retrospective cohort study.
作者: Hengqi Liu.;Hanning Liu.;Ling Fan.;Yuntong Lan.;Ping Chen.;Ping He.;Cheng Huang.;Sai Gu.;Haofeng Li.;Qing Shi.;Chunhui Lan.;Yan Guo.
来源: BMC Gastroenterol. 2025年25卷1期852页
There is a lack of data on the effects of family-based Helicobacter pylori (H. pylori) infection control and management (FBCM) strategies in Southwest China. This study aimed to evaluate the two-year outcomes of these strategies in affected households.
564. Relationship between diet quality and inflammatory bowel disease: a systematic review of observational studies.
作者: Parisa Karimi.;Elmira Ramezani.;Shakila Dehghani.;Nastaran Mahmoudi Shirkoohi.;Ariyo Movahedi.;Mohammad Masoumvand.;Ali Jafarzadeh Esfehani.
来源: BMC Gastroenterol. 2025年25卷1期756页
Inflammatory bowel disease (IBD) is a prevalent digestive disorder, influenced by various factors, particularly dietary choices and overall diet quality. Various indices assess diet quality, yet their correlation with IBD severity and symptoms remains uncertain. This systematic review examines the relationship between IBD and diet quality, as measured by the Dietary Inflammatory Index (DII), Healthy Eating Index (HEI), and Diet Quality Index (DQI).
565. Enhanced Trainer Performance and Resident Learning Following Implementation of a Training the Colonoscopy Trainers Course.
作者: Robert A Mousset.;Wouter H de Vos Tot Nederveen Cappel.;Jurjen J Boonstra.;James C H Hardwick.;Jolein van der Kraan.;Jean-Pierre E N Pierie.;Paul L P Brand.;Alexandra M J Langers.
来源: Gastroenterology. 2026年170卷4期668-673页 567. Endoscopic Histoacryl injection with clips is associated with lower early rebleeding compared to Histoacryl injection alone in the treatment of gastric varices.
作者: Yingfeng Wei.;Shenggang Huang.;Chunping Zhu.;Jiaming Huang.
来源: BMC Gastroenterol. 2025年25卷1期850页
To assess whether Histoacryl injection with clips is superior to Histoacryl injection alone in terms of efficacy and safety.
568. Research waste among randomized clinical trials in endoscopic resection of gastrointestinal lesions: a cross-sectional study of ClinicalTrials.gov.
作者: Yun Dai.;Xue-Ting Li.;Yong-Shen Zheng.;Jin-Hai Chen.;Guo-Xing Xu.;Hai-Xing Wang.
来源: BMC Gastroenterol. 2025年25卷1期851页
To determine the association between the characteristics of randomized clinical trials (RCTs) on endoscopic resection and research waste, and to explore potential targets for improvement.
569. Global, regional, and national burden of gastric cancer attributable to smoking and a high-sodium diet from 1990 to 2021: a global burden of disease study 2021.
作者: Guangying Zhao.;Yan Liu.;Haojie Wang.;Yongjian Zhang.;Liang Shang.;Leping Li.
来源: BMC Gastroenterol. 2025年26卷1期52页
This study comprehensively assesses the global, regional, and national burden of gastric cancer (GC) attributable to smoking and a high-sodium diet from 1990 to 2021, aiming to promote healthy lifestyle habits and provide scientific evidence for policy-making.
570. Benchmarking sessile serrated lesion detection in colonoscopy: individual endoscopist performance has greater impact than specialty training - a retrospective analysis of 12,064 procedures.
Sessile serrated lesions (SSLs) are implicated in up to 30% of colorectal cancers through the serrated neoplasia pathway. Current guidelines lack established benchmarks for SSL detection rates (SSL-DR), with significant geographic variation reported internationally. The 2024 American Society for Gastrointestinal Endoscopy (ASGE) and American College of Gastroenterology (ACG) recommend a minimum SSL-DR of > 6% for patients aged ≥ 45, while the Gastroenterological Society of Australia (GESA) maintains a 4% minimum. This study aimed to determine optimal SSL-DR benchmarks for clinical practice, compare detection rates between gastroenterologists and general surgeons, and identify whether specialty training or individual endoscopist performance primarily drives detection variability.
571. Risk factors and prediction model for submucosal invasion in early protruding-type esophagogastric junction adenocarcinoma: conventional endoscopy combines with endoscopic ultrasonography.
作者: Lei Zhang.;Nana An.;Zhongfei Jia.;Xiuli Zheng.;Wenqian Ma.;Juntao Lu.;Limian Er.
来源: BMC Gastroenterol. 2025年26卷1期10页
Precise depth evaluation of protruding-type early esophagogastric junction adenocarcinoma (EGJAC) is critical for therapeutic planning. This study evaluated the diagnostic value of conventional endoscopy (CE) and endoscopic ultrasonography (EUS) for identifying suspected submucosal-invasive carcinomas and established a predictive model for SM2 invasion.
572. Prevalence and risk factors of metabolic dysfunction-associated fatty liver disease in the adult Georgian population: a nationwide multiregional clinic-based study.
In Georgia, the prevalence of MAFLD remains poorly defined, as evidence largely stems from small-scale hospital studies. This research used a nationwide multiregional clinic-based sample to estimate MAFLD prevalence and its associated factors.
573. The role of fecal calprotectin in assessing response to advanced medical treatments for inflammatory bowel diseases: a review of the literature.
作者: Alessandro Vitello.;Olga M Nardone.;Giulio Calabrese.;Salvatore M Carnazzo.;Carlo D Maida.;Daryl Ramai.;Antonio Facciorusso.;Federico Bonomo.;Marcello Maida.
来源: Minerva Gastroenterol (Torino). 2026年72卷1期51-59页
In the era of treat-to-target (T2T), there is an urgent need for surrogate non-invasive markers to monitor patients with inflammatory bowel diseases (IBD). Fecal calprotectin (FC), a non-invasive biomarker reflecting intestinal inflammation, holds potential for improving treatment monitoring. This narrative review aims to provide an overview of the role of FC in assessing responses to biological therapies and the new small molecules.
576. Comprehensive nutritional management incorporating home-based dietary consultation improves hepatic encephalopathy in cirrhotic patients: a retrospective cohort study.
作者: Qing Zhao.;Jiangqiang Xiao.;Qin Yin.;Yue Xu.;Jiashu Yao.;Xiaotian Chen.;Ming Zhang.;Bo Gao.
来源: BMC Gastroenterol. 2025年26卷1期6页
Few studies have clinically demonstrated the benefits of comprehensive nutritional management incorporating home-based dietary consultation in patients with cirrhosis. This study investigates whether such management can improve the prognosis of cirrhotic patients.
577. Comparative efficacy of neoadjuvant imatinib therapy in gastric versus rectal gastrointestinal stromal tumors: a two-center retrospective cohort study.
作者: Jin-Hu Chen.;Zhi-Ming Cai.;Zhen-Rong Yang.;Tao Lin.;Shi-Chai Hong.;Xin-Cheng Su.;Yue-Ming Lin.;Lu Lin.;Zai-Sheng Ye.;Yong-Jian Zhou.
来源: BMC Gastroenterol. 2025年26卷1期8页
This study aimed to evaluate and compare tumor response, survival outcomes, and prognostic factors in gastric versus rectal GIST patients treated with neoadjuvant IM.
578. Evaluating The Impact of Ring Augmentation In Sleeve Gastrectomy: A Retrospective Propensity-weighted Cohort Study.
作者: Mohamed Hany.;Islam Mohamed Awad Sedik.;Medhat Anwar.;Rabie Abd Elwahed.;Alaa Hamza.;Mohamed Samir.
来源: BMC Gastroenterol. 2025年25卷1期857页
Sleeve gastrectomy (SG) is the most commonly performed metabolic surgery for obesity but is associated with long-term recurrent weight gain (RWG) and recurrence of comorbidities. Ring-augmented sleeve gastrectomy (RASG) has been proposed to improve weight durability by preventing gastric dilation and loss of restriction.
579. Effect of carbonated water on esophageal high-resolution manometry metrics: a retrospective study.
With the introduction of high-resolution manometry (HRM), esophageal motility disorders (EMDs) are now better understood, allowing for a more effective treatment. Carbonated water use was suggested to change esophageal motility. Hence, this study sought to determine the effect of carbonated water on esophagus HRM. In this retrospective study, we used manometry to evaluate the effects of carbonated water on esophageal movement and to investigate the potential impact on the diagnosis and interpretation of motility disorders.
580. Association between duration of alcohol consumption and risk of hematemesis in patients with alcoholic cirrhosis complicated by esophagogastric variceal bleeding: a case-control study.
作者: Siyuan Ding.;Shengyan Lu.;Liyuan Cui.;Jiayu Li.;Xiaolei Qin.;Xu Liu.
来源: BMC Gastroenterol. 2025年25卷1期849页
To investigate the correlation between drinking patterns and the occurrence of hematemesis in patients with alcoholic cirrhosis complicated by esophagogastric variceal bleeding (EVB).
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