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521. Relationship of D-dimer with survival and metastasis in gastric cancer patients: a meta-analysis and systematic review.
作者: Xiaofei Cheng.;Yang Zhang.;Xingyuan Li.;Zhenning Xu.;Yaolin Chen.
来源: BMC Gastroenterol. 2025年26卷1期30页
D-dimer predicts survival in patients with digestive cancers. However, comprehensive analysis focused on gastric cancer patients is lacking. This meta-analysis aimed to investigate the association of D-dimer with survival in gastric cancer patients.
522. The causal relationship between body mass index and perianal abscess: a Mendelian randomization study.
Observational studies suggest an association between elevated body mass index (BMI) and perianal abscess risk, but residual confounding and reverse causality limit causal inference. Mendelian randomization (MR) offers a robust approach to assess causality by leveraging genetic variants as instrumental variables. This study aimed to evaluate the causal relationship between BMI and perianal abscess using a MR framework.
524. Comparative efficacy of different diet modalities on metabolic profiles and liver functions in metabolic dysfunction-associated fatty liver disease: a network meta-analysis.
作者: Jiahui Zou.;Fei Tian.;Shuqing Cui.;Jing Hou.;Zhenhua Li.;Yaochen Wei.;Haozhe Cui.;Yunpeng Li.;Shuanghao Zhou.;Zechao He.;Xiangming Ma.
来源: BMC Gastroenterol. 2025年26卷1期25页
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a global public health challenge that is primarily managed through lifestyle interventions, particularly diet. This network meta-analysis aimed to thoroughly evaluate the effectiveness of four different dietary patterns: Mediterranean diet (MD), intermittent fasting (IF), Dietary Approaches to Stop Hypertension (DASH), and low-fat diet (LF) in improving liver function and metabolic profiles in adults diagnosed with MAFLD.
525. Analysis of risk factors and correlation between the degree of hepatic steatosis and fibrosis in patients with metabolic dysfunction-associated steatohepatitis.
作者: Xiaojin Yang.;Desheng Xie.;Yao Du.;DongHong Zhang.;Houji Chen.;Yinghua Yuan.
来源: BMC Gastroenterol. 2025年26卷1期28页
Metabolic dysfunction-associated steatohepatitis (MASH) is a chronic metabolic liver disease. This study sought to investigate risk factors and correlation between degree of hepatic steatosis and fibrosis in patients with MASH.
526. The ratio of GGT to PLT indices is a predictive factor for the progression of liver fibrosis in NA-treated chronic hepatitis B patients with advanced fibrosis plus PEG-IFN α-2a therapy: a case-control study.
作者: Ling Li.;Huili Li.;Yiru Zhao.;Lisha Shi.;Mireyi Suwanbai.;Liying Ren.;Guojun Li.;Xiucheng Pan.
来源: BMC Gastroenterol. 2025年26卷1期27页
Combination therapy with pegylated interferon α-2a (PEG-IFN α-2a) and nucleoside analogue (NA) has been shown to improve liver histology in patients with chronic hepatitis B (CHB) and hepatic fibrosis. PEG-IFN α-2a effectiveness was assessed in NA-treated CHB patients with advanced fibrosis/compensated cirrhosis.
527. Changes of bone, adipose, and muscle-related body compositions in gastric cancers after gastrectomy using deep learning based automatic segmentation.
作者: Mengying Xu.;Dan Liu.;Mengze Zhang.;Song Liu.;Zhengyang Zhou.
来源: BMC Gastroenterol. 2025年26卷1期26页
To investigate bone, adipose, and muscle-related body compositions changes in gastric cancers (GCs) 12 months after gastrectomy utilizing an artificial intelligence (AI) based segmentation tool and to conduct subgroup analyses based on clinicopathological characteristics.
531. Clusterin Drives Fiber Endocytosis by Mesothelial Cells to Resolve Liver Fibrosis.
作者: Minjun Wang.;Fei Chen.;Junling Gao.;Qinggui Liu.;Zhixuan Li.;Qingjie Kong.;Yanfang Liu.;Yan Pang.;Zijun Wang.;Ye Zhou.;Liyuan Zhang.;Kaiwei Jia.;Shan Lu.;Shanrong Liu.;Jihang Yuan.;Xing He.;Hui Liu.;Xiang Li.;Jin Hou.
来源: Gastroenterology. 2026年170卷3期569-583页
Liver fibrosis, a common outcome of chronic liver diseases, is generally considered irreversible. Upregulation of clusterin (CLU), a secreted glycoprotein, occurs in several degenerative diseases and is suggested to have protective effects; however, its potential in treating or reversing liver fibrosis requires investigation.
532. Etiology of cirrhosis is associated with risk of hepatic decompensation and hepatocellular carcinoma.
作者: Michelle Ng.;Olgert Bardhi.;Krystal Lai.;Eden Koo.;Sruthi Yekkaluri.;Kevin Bass.;Guruveer Bhamra.;Pojsakorn Danpanichkul.;Lisa Quirk.;Ju Dong Yang.;Jeremy Louissaint.;Thomas A Kerr.;Amit G Singal.
来源: BMC Gastroenterol. 2025年26卷1期22页
The impact of the changing epidemiology from viral to non-viral etiologies of cirrhosis on the burden of liver-related complications remains unclear.
533. Efficacy and safety of ultraviolet C therapy for the eradication of Helicobacter pylori.
作者: Ming'e Wu.;Yan Li.;Guxiang Zhou.;Zhenyu Li.;Rongxin He.;Qingqing Yang.;Mengyun Ke.;Nana Zhang.;Xiaoyan Zeng.;Yi Lyu.
来源: BMC Gastroenterol. 2025年26卷1期29页
Helicobacter pylori (Hp) is a globally prevalent gastrointestinal pathogen and a major etiological agent in various digestive tract disorders. Ultra violet C (UVC) light represents a promising physical modality for the treatment of Hp infection, owing to its capacity for non-invasive endoscopic delivery to eradicate the bacterium within the gastric environment.
534. Macroscopic growth patterns and their molecular implications in gastric carcinoma: toward risk stratification via borrmann classification.
作者: Gizem Issin.;Fatih Demir.;Diren Vuslat Cagatay.;Irem Guvendir Bakkaloglu.;Mehmet Gamsizkan.;Zeliha Yildiz.;Ismail Yilmaz.;Sevilay Ozmen.;Itir Ebru Zemheri.;Murat Demiriz.;Ilyas Sayar.;Armagan Gunal.
来源: BMC Gastroenterol. 2025年26卷1期20页
Gastric carcinoma (GC) is a heterogeneous disease with diverse histopathological and molecular features. The Borrmann classification, which reflects the macroscopic growth pattern, has potential value in correlating with molecular characteristics and predicting disease extent and prognosis. However, its relationship with GC molecular subtypes remains incompletely defined. In the present study, we attempted to assess the relationship between Borrmann classification and clinical, pathological, and molecular findings in GC, as well as its impact on overall survival.
535. An Exosome-Based Liquid Biopsy for the Detection of Early-Onset Colorectal Cancer: The ENCODER Multicenter Study.
作者: Alessandro Mannucci.;Francesc Balaguer.;Yasuhide Yamada.;Takeshi Nagasaka.;Yuji Toiyama.;Yoshinaga Okugawa.;Marc Martí-Gallostra.;Marta Jiménez-Toscano.;Rosario Vidal-Tocino.;Fernando Jiménez.;Jose Perea.;Enrique Quintero.;C Richard Boland.;Giulia Martina Cavestro.;Ajay Goel.; .
来源: Gastroenterology. 2026年170卷2期330-343页
The incidence of early-onset colorectal cancer (EOCRC; diagnosed before age 50 years) continues to increase, now standing as the leading cause of cancer-related deaths in young men. Screening participation in young adults remains low, but a noninvasive test may help.
536. Correction: Compliance and yield of follow-up colonoscopy after a positive FIT in real-life practice: a university hospital experience.
作者: Fady Daniel.;Nada Hamieh.;Batoul Abdallah.;Fayrouz Hachicho.;Dima Malak.;Wafaa Khaled.;Moustafa Al Hattab.;Hassan Sinan.;Omar Mahmoud.;Mohamad Ali Ibrahim.;Ali R Chaitou.;Rudy Mrad.;Ala I Sharara.
来源: BMC Gastroenterol. 2025年25卷1期855页 538. EUS-FNA with ROSE for pancreatic solid lesions: a single-center experience.
作者: Qin Lu.;Ting Dai.;Peng Liu.;Rongxing Shi.;Tingting He.;Wei Zhang.
来源: BMC Gastroenterol. 2025年26卷1期21页
Rapid On-Site Evaluation (ROSE) improves sample quality and diagnostic accuracy by allowing for immediate examination of collected specimens. In this paper we evaluated diagnostic value of Endoscopic Ultrasound Guided Fine Needle Aspiration (EUS-FNA) and ROSE for pancreatic space occupying lesions and the rapidity of ROSE.
539. Correction: Early lactate and its metabolism for predicting persistent renal failure in patients with acute pancreatitis: a retrospective observational study.
作者: Jianhua Wan.;Huajing Ke.;Wenhua He.;Yin Zhu.;Nonghua Lu.;Liang Xia.
来源: BMC Gastroenterol. 2025年25卷1期854页 540. Application of laparoscopic liver surgery techniques in laparoscopic thermal ablation of liver tumors.
作者: Yongkun Li.;Chenhao Jiang.;Zheng Wang.;Lei Liu.;Ke Wu.;Lu Zheng.;Nan You.
来源: BMC Gastroenterol. 2025年26卷1期19页
The utility of laparoscopic thermal ablation (LTA) for liver tumors is restricted when lesions are unfavorably located. To address this challenge, our study investigated the feasibility and safety of enhancing LTA with laparoscopic liver surgery techniques (LLSTs).
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