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341. Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure.
作者: Yoav Dori.;Erin Pinto.;Lauren Biroc.;Matthew J Gillespie.;Ryan Callahan.;Jessica Tang.;Michael L O'Byrne.;Brooke Ford.;Danish Vaiyani.;Aaron G DeWitt.;Denise Merrill.;Digvijay Shinde.;Emmanuelle Favilla.;Rachel Shustak.;Fernando A Escobar.;Ganesh Krishnamurthy.;Abhay Srinivasan.;Jonathan J Rome.;Christopher L Smith.
来源: Circ Cardiovasc Interv. 2025年18卷10期e015336页
External drainage of the thoracic duct can temporarily reduce tissue congestion and improve symptoms in patients with heart failure. However, loss of fluid limits the duration of this approach. Here, we report on our initial experience with thoracic duct drainage and autotransfusion in patients with elevated central venous pressure.
342. Mitochondrial sORF-Encoded Peptide MODICA Protects the Heart From Doxorubicin-Induced Cardiac Injury by Suppressing VDAC Oligomerization.
作者: Jialing Wu.;Kang Li.;Youchen Yan.;Xingfeng Xu.;Ting Xu.;He Xu.;Huimin Zhou.;Tailai Du.;Yan Li.;Chen Liu.;Xinxue Liao.;Yugang Dong.;Jing-Song Ou.;Yili Chen.;Zhan-Peng Huang.
来源: Circ Heart Fail. 2025年18卷11期e013381页
Doxorubicin (DOX) cardiotoxicity increases cardiovascular risk in cancer patients, mainly through mitochondrial damage. However, the underlying mechanisms remain unclear, and whether mitochondrial short open reading frame-encoded peptides can mitigate DOX-induced cardiotoxicity is unknown.
343. 2D Speckle Tracking Strain Echocardiography in Multisystem Inflammatory Syndrome in Children: A Multicenter Analysis From the MUSIC Study.
作者: Francesca Sperotto.;Valiantsina Kazlova.;Felicia L Trachtenberg.;Dongngan T Truong.;Sanjeev Aggarwal.;Joseph R Block.;Tamara T Bradford.;Sujatha Buddhe.;Audrey Dionne.;Andreea Dragulescu.;Kanwal M Farooqi.;Daniel E Forsha.;Therese M Giglia.;Ian F Golding.;Keren Hasbani.;Pei-Ni Jone.;Anita Krishnan.;Sean M Lang.;Carol A McFarland.;Elizabeth C Mitchell.;Elias Moussi Saad.;Todd T Nowlen.;Ricardo H Pignatelli.;Scott Pletzer.;Ryan Serrano.;Divya Shakti.;Shubhika Srivastava.;Thor Thorsson.;Jodie K Votava-Smith.;Hunter C Wilson.;Jane W Newburger.;Kevin G Friedman.; .
来源: Circ Cardiovasc Imaging. 2025年18卷9期e017620页
2D-speckle tracking echocardiography may help detect subclinical ventricular dysfunction, but data in multisystem inflammatory syndrome in children (MIS-C) are scarce. We investigated left ventricular (LV) strain parameters in MIS-C and their association with outcomes.
344. Global Microvascular Dysfunction and Incomplete Recovery in Takotsubo Syndrome: Insights From Serial PET Imaging.
作者: Yoshito Kadoya.;Aun Yeong Chong.;Gary R Small.;Benjamin J W Chow.;Robert A deKemp.;Terrence D Ruddy.;Rob S Beanlands.;Andrew M Crean.
来源: Circ Cardiovasc Imaging. 2025年18卷10期e018266页
The proposed cause of Takotsubo syndrome (TTS) includes coronary microvascular dysfunction. This study aimed to investigate coronary microvascular dysfunction and its recovery in patients with TTS using serial positron emission tomography myocardial perfusion imaging.
345. Representation of Older Adults and Women in Randomized Trials of Noninvasive Imaging for Chest Pain.
作者: Phillip Lim.;Tansu Eris.;Leslee J Shaw.;Laura P Gelfman.;Annetine C Gelijns.;Alan J Moskowitz.;Emilia Bagiella.;Fay Y Lin.;Deepak L Bhatt.;Gregg W Stone.;R Sean Morrison.;David J Cohen.;Michael G Nanna.;Karen P Alexander.;Krishna K Patel.
来源: Circ Cardiovasc Imaging. 2025年18卷10期e018295页
Noninvasive imaging is widely used for both initial diagnosis and guided management of ischemic heart disease. Older adults and women with ischemic heart disease may have different responses to imaging and subsequent treatment outcomes compared to younger adults and men. We aimed to study the representation of older adults and women in randomized controlled trials of noninvasive imaging among patients with acute and stable chest pain.
347. Atrial Mechanics in Heart Failure With Preserved Ejection Fraction: Effect of a No-Implant Interatrial Shunt.
作者: Michal Laufer-Perl.;Nir Flint.;Yaron Arbel.;Fawaz Alenezi.;Veraprapas Kittipibul.;Dmitry Yaranov.;Tamaz Shaburishvili.;Rohit Amin.;Marat Fudim.
来源: Circ Heart Fail. 2025年18卷10期e012573页
The atria play an important role in the pathophysiology of heart failure with preserved ejection fraction. Decreased left atrial strain is associated with worse clinical outcomes. The impact of no-implant interatrial shunting on atrial structure and function has not been described.
348. Insight Into the Formation of Apical Aneurysm in Hypertrophic Cardiomyopathy by Comprehensive Coronary Physiological Assessment.
作者: Takashi Hiruma.;Hiroyuki Kiriyama.;Shun Kitamura.;Shun Minatsuki.;Norihiko Takeda.
来源: Circ Heart Fail. 2025年18卷10期e013043页 349. Outcomes of Endovascular Revascularization for Chronic Limb-Threatening Ischemia in Medicare Advantage and Medicare Fee-For-Service Beneficiaries.
作者: Katerina Dangas.;Joseph M Kim.;Siling Li.;Yang Song.;Andrew S Oseran.;Robert W Yeh.;Rishi K Wadhera.;Eric A Secemsky.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷10期e012099页 350. Hemodynamic Super-Response to Mechanical Thrombectomy in Patients With Intermediate-Risk Pulmonary Embolism.
作者: Eugene Yuriditsky.;Robert S Zhang.;Peter Zhang.;Hannah P Truong.;Lindsay Elbaum.;Allison A Greco.;Radu Postelnicu.;James M Horowitz.;Samuel Bernard.;Vikramjit Mukherjee.;Kerry Hena.;Carlos L Alviar.;Norma M Keller.;Sripal Bangalore.
来源: Circ Cardiovasc Interv. 2025年18卷10期e015235页
Among patients with intermediate-risk pulmonary embolism undergoing mechanical thrombectomy, the mean change in cardiac index (CI) is modest. We sought to identify variables associated with a hemodynamic super-response or a CI increase of ≥25% postthrombectomy.
352. MYCN Regulates Cardiomyocyte Proliferation, Metabolism, and Regeneration in the Mammalian Heart.
作者: Satyabrata Das.;Thijs A Larson.;Javier E Sierra-Pagan.;Xiao Ma.;Qinglu Li.;Kidus Hailemariam.;Riley J Leonard.;Tamas Alexy.;Wuming Gong.;Mary G Garry.;Jianyi Zhang.;Daniel J Garry.
来源: Circulation. 2025年152卷9期635-638页 353. Letter by Shi et al Regarding Article "Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality".356. Response by Silbernagel et al to Letters Regarding Article, "Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality".358. Letter by Huang Regarding Article, "Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality".359. Hemodynamic Effects of Transcatheter Tricuspid Valve Annuloplasty With Cardioband and Their Associations With Clinical Outcomes.
作者: Jan Althoff.;Alev Kalkan.;Thorsten Gietzen.;Karl Finke.;Caroline Hasse.;Jennifer von Stein.;Jan Wrobel.;Athanasios Feidakis.;Laura Marx.;Stephan Baldus.;Maria I Körber.;Roman Pfister.;Christos Iliadis.
来源: Circ Cardiovasc Interv. 2025年18卷9期e015702页
Transcatheter tricuspid valve annuloplasty (TTVA) with the Cardioband system is a safe and effective option for high-risk patients with symptomatic severe tricuspid regurgitation (TR). Hemodynamics play a crucial role in these patients. However, it remains unclear if hemodynamic changes after TTVA are linked to clinical outcomes.
360. Technical Advances and Outcomes of Fetal Atrial Septal Intervention for Restrictive or Intact Atrial Septum.
作者: Betul Yilmaz Furtun.;Mira K Trivedi.;Patrick Day.;Pamela Ketawaroo.;Michelle Mathevosian.;Jeel Mehta.;Magda Sanz-Cortes.;Carolyn A Altman.;Srinath Gowda.;Caitlin Dooley Sutton.;David G Mann.;Roopali Varma Donepudi.;Ahmed A Nassr.;Lindsay Eilers.;Claire Naus.;Gary E Stapleton.;Jeffrey S Heinle.;Yishay Orr.;Rocky Tsang.;Heather Dickerson.;Nancy A Ayres.;Athar M Qureshi.;Michael A Belfort.;Shaine A Morris.
来源: Circ Cardiovasc Interv. 2025年18卷9期e015209页
Infants with hypoplastic left heart syndrome with severely restrictive or intact atrial septum (R/IAS) have low survival. In-utero creation of an atrial septal communication has been reported, with high complication rates.
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