283. Tenecteplase for Acute Non-Large Vessel Occlusion 4.5 to 24 Hours After Ischemic Stroke: The OPTION Randomized Clinical Trial.
作者: Gaoting Ma.;Ran Mo.;Yingting Zuo.;Qingfeng Ma.;Guangjian Zhao.;Xiaoxi Yao.;Ji Liang.;Li Zhou.;Yong He.;Faqing Long.;Zhengzhou Yuan.;Lei Liu.;Guosheng Han.;Yan Tan.;Zhibing Ai.;Chunsheng Cai.;Juan Liu.;Liyong Zhang.;Haihua Yang.;Tingyu Yi.;Li Li.;Yao Fu.;Yanxing Zhang.;Xiangzhong Shao.;Zhipeng Yu.;Saizhen Wu.;Yanqiu Du.;Lingqun Mao.;Hongling Guo.;Xufeng Chen.;Yifei Chen.;Qiong Zhao.;Liyi Chi.;Yi Liu.;Haochun Zhang.;Guangzong Li.;Shujuan Meng.;Yifan Wu.;Jieying Wu.;Ziying Jiang.;Shaoyuan Lei.;Daiquan Gao.;Lianmei Zhong.;Jens Fiehler.;Duolao Wang.;Thanh N Nguyen.;Jeffrey L Saver.;Junwei Hao.; .
来源: JAMA. 2026年335卷13期1137-1147页
The efficacy and safety of intravenous tenecteplase in non-large vessel occlusion acute ischemic stroke beyond 4.5 hours after symptom onset remain uncertain.
295. Trends and Disparities in Heat-Related Emergency Medical Services Activations.
作者: Chris Chaeha Lim.;Jonathan A Race.;Parneet Kaur.;Honghyok Kim.;Ran Wei.;Xiaojiang Li.;Ladd Keith.;Lynn B Gerald.;Brian Drummond.;Noah M Tolby.;N Clay Mann.
来源: JAMA. 2026年335卷9期818-820页 300. Opportunistic Salpingectomy for Prevention of Tubo-Ovarian Carcinoma: The European Society of Gynaecological Oncology Consensus Statements.
作者: Jurgen M Piek.;Jolijn Schauwaert.;Laura Burney Ellis.;Ignacio Zapardiel.;François Planchamp.;Kata Koblos.;Joanna Kacperczyk-Bartnik.;Sarah J Bowden.;Houssein El Hajj.;Mihaela Grigore.;Miranda P Steenbeek.;Nicolò Bizzarri.;Maria Kyrgiou.;Murat Gültekin.
来源: JAMA. 2026年335卷10期894-902页
The fallopian tube epithelium has been demonstrated to be an important source of tubo-ovarian carcinoma. Therefore, removal of the fallopian tubes during unrelated pelvic or abdominal surgery (opportunistic salpingectomy) can potentially lower future ovarian cancer risk.
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