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261. Bronchiectasis in Patients With Inflammatory Bowel Diseases: Prevalence, Predictors, and Clinical Characteristics.
作者: Ophir Freund.;Amir Bar-Shai.;Arik Alkhazov.;Dana Stav.;Yitzhac Hadad.;Tal Moshe Perluk.;Neta Sror.;Ayal Hirsch.;Yulia Ron.;Tamar Thurm.;Amit Herling.;Haim Leibovitzh.;Nitsan Maharshak.;Nathaniel Aviv Cohen.
来源: Chest. 2025年168卷2期317-325页
Inflammatory bowel diseases (IBDs) are known to be associated with bronchiectasis (BE). However, data on patients with inflammatory bowel disease-related bronchiectasis (IBD-BE) are limited.
262. Association of Timely Spirometry With Lower All-Cause Mortality: A Nationwide Obstructive Cohort Study.
Although spirometry is the gold standard for diagnosing COPD, it is underused in clinical practice.
263. CT Emphysema Subtypes and Cardiac Hemodynamics Estimated on MRI: The Multi-Ethnic Study of Atherosclerosis COPD Study.
作者: Emilia A Hermann.;Jesse X Yang.;Elsa Angelini.;Pallavi Balte.;David A Bluemke.;James Carr.;Katja Derlin.;Antoinette S Gomes.;Mohammadali Habibi.;Eric A Hoffman.;Chris Johns.;Steven M Kawut.;David G Kiely.;Andrew Laine.;Joao A C Lima.;Martin R Prince.;Benjamin Smith.;Jens Vogel-Claussen.;Karol Watson.;Jim M Wild.;Andrew J Swift.;R Graham Barr.
来源: Chest. 2025年168卷2期364-378页
COPD is traditionally associated with pulmonary hypertension, but treatments targeting elevated pulmonary artery pressure in COPD have largely failed, possibly due to an incomplete understanding of subphenotypes of the disease.
264. US Physicians' Perceived Impacts of Abortion Bans in Pulmonary and Critical Care Medicine.
作者: Katrina E Hauschildt.;Avnee J Kumar.;Elizabeth M Viglianti.;Kelly C Vranas.;Taylor Bernstein.;Leslie Moroz.;Theodore J Iwashyna.; .
来源: Chest. 2025年168卷2期462-473页
Eighteen US states implemented abortion bans between 2022 and 2024. Although emerging evidence shows bans have impacted obstetrics and gynecology, little is known about their impact on other specialties. We hypothesize that pulmonary and critical care medicine may be adversely impacted due to the time-sensitive, high-acuity needs of their patients.
265. Accuracy of Pulse Oximetry and Risk Factors Associated With Discrepancy From Arterial Oxygenation in Asian Patients in the ICU: An Observational Study.
作者: Toshishige Takagi.;Tomoko Fujii.;Sae Nakamura.;Yusuke Tsutsumi.;Shoichi Uezono.
来源: Chest. 2025年168卷3期650-660页
Oxygen administration is often guided by pulse oximeter readings. However, inaccuracies have been reported, particularly in patients with darker skin tones. During the COVID-19 pandemic, racial and ethnic disparities in hypoxemia detection emerged, with studies showing a higher incidence of hidden hypoxemia in Black and Hispanic patients. However, limited data exist regarding the Asian population.
266. Inhaled Menthol for Dyspnea Relief During Cycle Exercise in COPD: A Randomized Trial.
作者: Michele R Schaeffer.;Lucas Vanden Bossche.;Kaat Beckers.;Kristin Verbeke.;Wim Janssens.;Dennis Jensen.;Jem I Arnold.;Andreas von Leupoldt.;Daniel Langer.
来源: Chest. 2025年168卷2期390-401页
Menthol inhalation (MI) lowers dyspnea ratings during loaded breathing in COPD and cycle exercise in healthy adults. Proposed mechanisms include stimulation of cold receptors in the upper airways, modulating perception of breathing-related effort and airflow.
267. Low-Intensity vs Moderate-Intensity Anticoagulation for Venovenous Extracorporeal Membrane Oxygenation: The Strategies for Anticoagulation During Venovenous Extracorporeal Membrane Oxygenation Pilot Trial.
作者: Whitney D Gannon.;Elias H Pratt.;Melissa A Vogelsong.;Wren H Adkisson.;Matthew Bacchetta.;Sarah L Bloom.;Daniel J Ford.;Brandon A Guenthart.;Janna S Landsperger.;Edward T Qian.;Craig R Rackley.;Todd W Rice.;Vikram Fielding-Singh.;John W Stokes.;Joanna L Stollings.;Matthew W Semler.;Jonathan D Casey.; .
来源: Chest. 2025年168卷3期639-649页
Bleeding is a common and sometimes fatal complication of venovenous extracorporeal membrane oxygenation (ECMO). Whether lowering the intensity of anticoagulation during venovenous ECMO is safe or effective is unknown.
269. Spirometry Abnormalities and Immune Dysfunction Among Adolescents With and Without HIV in Kenya: A Cohort Study.
作者: Laura E Ellington.;Elizabeth Maleche-Obimbo.;Brandon L Guthrie.;Margaret Rosenfeld.;T Eoin West.;Christine J McGrath.;Judith Lukorito.;Christine Njiru.;Anthony Cagle.;Sherry Eskander.;Michael H Chung.;Kristina Crothers.;Engi F Attia.
来源: Chest. 2025年168卷2期449-461页
Chronic lung disease and its association with immune dysfunction is characterized poorly among adolescents with HIV (AWHIVs).
270. Contribution of Peripheral Airways Dysfunction to Poor Quality of Life in Sarcoidosis.
作者: Dimitrios Toumpanakis.;Konstantinos Karagiannis.;Paolo Paredi.;Andras Bikov.;Martina Bonifazi.;Harpreet K Lota.;Harpal Kalsi.;Cosetta Minelli.;Nikolaos Dikaios.;George A Kastis.;Peter J Barnes.;Athol U Wells.;Omar S Usmani.;Elisabetta A Renzoni.
来源: Chest. 2025年168卷2期423-434页
Sarcoidosis is characterized by reduced quality of life (QoL), yet QoL is correlated poorly to conventional spirometric lung function tests.
271. Phenotyping Exertional Breathlessness Using Cardiopulmonary Cycle Exercise Testing in People With Chronic Airflow Limitation.
作者: Magnus Ekström.;Pei Zhi Li.;Hayley Lewthwaite.;Jean Bourbeau.;Wan C Tan.;Dennis Jensen.; .
来源: Chest. 2025年168卷2期379-389页
Exertional breathlessness is a cardinal symptom of people with chronic airflow limitation (CAL) and can be evaluated using cardiopulmonary exercise testing (CPET).
272. Interventions to Improve Adherence to Clinical Guidelines for the Management and Follow-Up of Pulmonary Nodules: A Systematic Review.
作者: Justin Aunger.;Kay Por Yip.;Kamen Dosanjh.;Katie Scandrett.;Bianca Ungureanu.;Michael Newnham.;Alice M Turner.
来源: Chest. 2025年168卷1期248-268页
Lung cancer is the leading cause of global cancer mortality. It is also the third most common cancer in the United Kingdom and the most prevalent worldwide. Pulmonary nodules can indicate early-stage lung cancer, but adherence to guidelines for radiologic surveillance is suboptimal, which affects early detection and treatment. Although interventions have been developed to improve follow-up, it remains unclear which approaches are most effective.
275. Response.
作者: Zhaolong Feng.;Guoxian Li.;Qida He.;Na Sun.;Tongxing Li.;Qiang Han.;Hanqing Zhao.;Ze Ma.;Mengtong Sun.;Boyan Liu.;Yu Wang.;Zexin Lou.;Siqian Ma.;Yujie Shi.;Jianing Li.;Ziqing Sun.;Miao Jiang.;Yueping Shen.
来源: Chest. 2025年167卷3期e98-e99页 279. A 73-Year-Old Man With Right-Sided Chest Pain and Dyspnea.
A 73-year-old man presented with a 2-week history of intermittent right-sided chest pain, cough, and progressive dyspnea on exertion. He reported subjective weight loss and anorexia with early satiety over the preceding months. He denied any fevers, night sweats, or sick contacts. On further questioning, he had also noted some progressive abdominal distension, though denied any change in bowel habits, nausea, or vomiting. He had a history of hypertension and diabetes. He was a person who does not smoke and had worked in the construction industry for > 50 years prior. His daughter had passed away due to lung cancer.
280. A 52-Year-Old Woman With Shortness of Breath and Left Lower Back Pain.
作者: Faraz Badar.;Harith Al-Ataby.;Mohammed Al-Azzawi.;Mohamed Omballi.
来源: Chest. 2025年167卷3期e83-e87页
A 52-year-old woman presented to the clinic with progressively worsening shortness of breath associated with intermittent pleuritic left lower back pain for the past 6 months. The patient denied any cough, hemoptysis, fever, chills, or weight loss. She had a history of smoking cigarettes for more than 10 years but quit almost 20 years ago. An outpatient chest radiograph was obtained, and it suggested consolidation of the left lower lobe. The patient was treated empirically with amoxicillin-clavulanate for 2 weeks without improvement.
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