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9981. [The relation between DNA replication error and clinicopathological features of colorectal carcinoma].
To study the relationship between DNA replication error and development of colorectal carcinoma (CRC).
9982. [Microsatellite instability in gastric carcinoma and intestinal metaplasia].
To investigate the role of microsatellite instability (MSI) in the carcinogenesis and development of gastric cancer (GC).
9983. [A study on the tumor suppressing effect of a specific point mutant p53 minigene in the expression regulated model with a tetracycline-transactivative response promoter].
To establish a tetracycline-regulated expression model and to determine and verify whether a specific point mutant type p53 minigene, containing an Arg-->Leu substitution at amino acid 172, possesses a suppressing effect on human lung cancer.
9984. [p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
To investigate the relationship between p53 gene mutations and mouse skin tumors induced by three-step carcinogenesis.
9985. [A study of p16 gene and its protein expression in rhabdomyosarcoma].
To evaluate the relationship between alteration of p16 gene, its protein expression and the pathogenesis and development of rhabdomyosarcoma (RMS).
9986. [p53 alterations in human lung cancer and their correlation with clinicopathological features and prognosis].
To investigate p53 protein accumulations and p53 mutations in squamous cell carcinoma and adenocarcinoma of the lung and their correlation with clinicopathological features and prognosis.
9987. [Hodgkin's disease: Ig gene rearrangements in single H/R-s cells].
To investigate the origin and cell lineage of Hodgkin/Reed-Sternberg (H/R-S) cells from various subtypes of Hodgkin's disease (HD).
9988. [Expression of cytotoxic-granule-associated protein TIA-1 in nasal NK/T cell lymphomas and lymphoid hyperplasia].
27 cases of nasal NK/T cell lymphomas were studied for the expression of the cytotoxic-granule-associated protein TIA-1, its immunophenotype, genotype and Epstein-Barr virus infection status.
9989. [Detection of T-cell receptor gamma chain gene rearrangement in midline T-cell lymphomas by PCR method].
To investigate the clonality of midline T-cell lymphoma.
9990. [Apoptosis induced by adenovirus-mediated wild-type p53 expression in human pancreatic cancer cells].
To investigate the biological effects of wtp53 expression on the growth rate and apoptosis of human pancreatic carcinoma.
9991. [Some critical points on current liver cancer research].9992. [Detection of MDM 2 and p 53 genes in rhabdomyosarcoma by in situ hybridization].
To observe the correlation between MDM2, p53 genes and the pathogenesis, clinical pathology and prognosis in rhabdomyosarcoma (RMS).
9993. [Detection of the p53 protein accumulation and p53 gene mutation in squamous cell carcinoma of the lung].
To investigate the effects of p53 protein accumulation and p53 gene mutation in the pathogenesis of squamous cell carcinoma of lung.
9994. [Expression and mutation of p53 and H-ras genes in the carcinogenesis and development of gastric adenocarcinoma induced by MNNG in rats].
To investigate the effect of p53 and H-ras genes in the carcinogenesis of and development of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Wistar rats.
9995. [The expression of plasminogen activator inhibitor-1 (PAI-1) gene in human astrocytomas].
To investigate the expression of PAI-1 gene and its clinical significance in human astrocytomas.
9996. [Construction of the internal standard RNA and DNA templates for MRP gene quantitative RT-PCR analysis].
To construct the internal standard RNA and DNA templates for quantitative reverse transcription-polymerase chain reaction (RT-PCR) and quantitatively measure the mRNA expression of MRP gene.
9997. [Effect of antisense oligodeoxynucleotide (ASODN) to PML-RAR alpha fusion gene on acute promyelocytic leukemia cell line NB4].
To study the effect of PML-RAR alpha expression on the proliferation and differentiation of NB4 cells, and explore the role of PML-RAR alpha fusion gene in the pathogenesis of acute promyelocytic leukemia (APL).
9998. [The effect of cytokines on the activation of T cells induced by B7-1-transfected leukemia cells].
To observe the effects of IL-12, IFN-gamma, IL-10 on the B7-1 expression of B7-1 transfected leukemia cells (K562 and HL-60) and on the IL-2 and IFN-gamma expression and production in the peripheral blood mononuclear cells(PBMC) induced by B7-1 transfected K562 and HL-60 cells.
9999. [New full length cDNA cloned from normal pituitary and pituitary tumors].
To clone new full length cDNA from normal pituitary and pituitary tumors.
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