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9821. [Methylation and expression of the p16 gene in endometrial carcinoma].
To analyse the relationship between methylation status of the 5' CpG island and mRNA expression of the p16 gene in endometrial carcinoma.
9822. [Establishment and biological characteristics of vincristine: resistant cell line from human squamous cell carcinoma].
To establish a VCR-resistant cell line from human squamous cell carcinoma.
9823. [p53 gene mutation determined by single-strand conformational polymorphism and DNA sequencing analysis in pleomorphic adenoma of salivary gland].
To detect p53 exon 6 mutation pattern in pleomorphic adenoma of salivary gland.
9824. [Expression of C-erbB-2 oncogene mRNA in salivary gland tumors].
To study relationship of C-erb-2 oncogene mRNA expression and histotype, tumorigenesis and biological behavior of salivary gland neoplasms.
9825. [Cloning of differentiation-related genes induced by all-trans retinoic acid(ATRA) from human lung cancer GLC-82 cell line].
Cloning of differentiation-related genes induced by all-trans retinoic acid(ATRA) from human lung cancer GLC-82 cell line.
9826. [Characteristics of high frequency 249 codon mutation of p53 gene in hepatocellular carcinoma in prevalent area of China].
To study the characteristic features of an unique hotspot missense mutation of the 249 codon of p53 gene demonstrated in human hepato-cellular carcinoma(HCC) in a region of high(Qidong) and low (Beijing) exposure to both hepatitis B virus (HBV) and aflatoxin B1 (AFB1) in China.
9827. [p53 mutations and protein overexpression in primary colorectal cancer and its liver metastasis].
To compare p53 status between primary and hepatic metastatic colorectal cancer in 34 patients.
9828. [Alterations of FHIT gene and p16 gene in lung cancer and metastatic hilar lymph nodes].
To investigate alterations of fragile histidine triad (FHIT) gene and p16 gene in lung cancer.
9829. [Mutation of human mismatch repair genes in hereditary nonpolyposis colorectal cancer (HNPCC) families].
To investigate germline mutations of mismatch repair genes hMLH1 and hMSH2 in 29 HNPCC families.
9830. [Effect of exogenous p16 gene on the growth of wild-type p53 human lung adenocarcinoma cells].
To study the effect of p16 gene on human adenocarcinoma cell lines and the posibility of exogenous p16 gene for gene therapy of lung cancer.
9831. [Study of microsatellite instability of colotectal cancer and its clinical significance].
To evaluate microsatellite instability (MI) of colorectal cancer in China.
9832. [A novel human DNA sequence with tumor metastasis suppressive activity].
To isolate human tumor metastasis suppressive DNA sequence and to study the molecular mechanisms regulating tumor metastasis.
9833. [RAB5A, a gene possibly related to metastasis of human carcinoma of the lung and stomach].
To study and isolate tumor metastasis-related genes, and to explore the molecular basis of metastasis of lung and gastric carcinoma.
9834. [p16 gene suppresses growth of human esophageal carcinoma cells].
To explore the effect of p16 gene on the growth inhibition of esophageal carcinoma cell line NEC.
9835. [Apoptosis of human gastric cancer cells induced by bcl-2 antisense oligodeoxynucleotides].
To study the regulation of bcl-2 gene expression and induction of apoptosis by bcl-2 antisense oligodeoxynucleotides (AS-ODN) on human gastric cancer cell line BGC-823 in vitro.
9836. [MAL gene is down-regulated substantially in human esophageal cancer].
To investigate the status of expression of MAL gene in human esophageal cancer.
9837. [Expression of GST-pi gene in human esophageal carcinogenesis].
To investigate the possible role of GST-pi in esophageal carcinogenesis.
9838. [The possible role of loss of heterozygosity at APC, MCC and DCC genetic loci in esophageal carcinoma].
To investigate the alterations of APC, MCC and DCC genes in human esophageal carcinoma.
9839. [Mutations of several tumor suppressor genes in primary retinoblastoma].
To study the status of several tumor suppressor genes in primary retinoblastoma.
9840. [Studies of microsatellite instability and loss of heterozygosity at chromosome 17 in non-small cell lung carcinoma].
To identify the presence of microsatellite instability (MI) and loss of heterozygosity (LOH) in non-small cell lung carcinoma (NSCLC).
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