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821. [Effect of (-)-epigallocatechin-3-gallate and 5-AZA-CdR on expression of X-linked inhibitor of apoptosis protein-associated factor 1 in human leukemia HL-60 and K562 cells].
作者: Yun-yan Huang.;Yan Xia.;Hai-xia Guo.;Wen-yi Li.
来源: Nan Fang Yi Ke Da Xue Xue Bao. 2008年28卷2期204-8页
To study the expression of X-linked inhibitor of apoptosis protein (XIAP)-associated factor 1 (Xaf1) in human leukemia HL-60 and K562 cells treated with interferon alpha (INFalpha) and the demethylating agent 5-AZA-CdR, and observe the synergetic antitumor effect of Xaf1 inducer and (-)-epigallocatechin-3-gallate (EGCG).
822. [Inhibition of bFGF gene expression and tumor angiogenesis of orthotopic implantation of human gastric carcinoma by N-desulfated heparin].
作者: Ming-xiang Chen.;Jin-lian Chen.;Jin-lai Lu.;Jing Hong.;Wei-xiong Chen.;Jin-shui Zhu.;Ni-wei Chen.;Jian-guo Geng.
来源: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008年25卷1期78-81页
To investigate the effect of N-desulfated heparin on tumor metastasis, tumor angiogenesis and basic fibroblast growth factor(bFGF) gene expression of orthotopically implanted human gastric carcinoma in NOD-SCID mice.
823. [Advances in interactions between glucocorticoid hormones and circadian gene expression].
Circadian rhythm, which is internally generated by cell autonomous biological clocks, has been greatly concerned in recent years. This circadian system in mammals is composed of a master pacemaker in the suprachiasmatic nucleus (SCN) of the hypothalamus and slave clocks in most peripheral cell types. The clock genes and their coding proteins compose the feed-back loops of the circadian system. Light and food are two major Zeitgebers to synchronize circadian clocks. Light can induce clock genes expression and glucocorticoids release in the adrenal gland, while glucocorticoids can slow down the food-induced phase-shifting of peripheral circadian oscillators, suggesting that a close relationships may exist between glucocorticoids and the circadian gene expression. This article briefly reviews the recent progress in the interactions between them and suggests the direction of future researches.
824. [Effects of insulin on proliferation and apoptosis of endometrial carcinoma cell].
作者: Jing Zhao.;Feng-Xia Xue.;Shao-Fang Hua.;Li-Zhi Zhang.
来源: Zhonghua Fu Chan Ke Za Zhi. 2007年42卷10期696-700页
To study the expression of insulin receptor (INSR) in endometrial cell line Ishikawa3-H-12, and the effects of insulin on proliferation, cell cycle distribution and apoptosis of Ishikawa3-H-12 cells.
825. [TNF-alpha upregulate MUC5AC mucin secretion through COX2/PGE2 mechanism].826. [Small interference RNAs directed against KDR gene inhibit the proliferation of breast cancer cells in vitro and in vivo].
作者: Xiao-jing Zhang.;Yin-lin Ge.;Lin Hou.;Quan Li.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008年24卷1期58-61页
To inhibit kinase insert domain-containing receptor (KDR) expression chemically modified siRNA in vitro and in vivo and to investigate the feasibility and specificity of gene therapy for breast cancer.
827. [Inhibitory effect of quercetin, rutin and puerarin on LDL oxidation induced by Cu2+].
作者: Rui Liu.;Fang Meng.;Huai Bai.;Yu Liu.;Cheng-Wei Tang.;Bing-Wen Liu.
来源: Zhongguo Zhong Yao Za Zhi. 2007年32卷19期2058-62页
To evaluate the inhibitory effect of quercetin, rutin and puerarin on the LDL oxidation induced by Cu2+ and to investigate their action on the prevention and treatment of atherosclerosis.
828. [Inhibition of curcumin on histone deacetylase and expression promotion of P21 (WAF1/CIP1) in HepG2 cells].
作者: Bi-Hua Lv.;Ling Zhang.;Chang-Cai Zhu.;Jing Liu.
来源: Zhongguo Zhong Yao Za Zhi. 2007年32卷19期2051-5页
To investigate the effect of curcumin (Cur) on histone deacetylase (HDAC1) and P21(WAF1/CIP1), a cyclin dependent kinase inhibitor, in HepG2 cells for exploring the mechanism of Cur in anti-cancer.
829. [Rapamycin affects eIF- 4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3].
作者: Chun-Yuan Chen.;Yue-Nu Sun.;Zuo-Cheng Yang.;Yan-Qiong Long.
来源: Zhongguo Dang Dai Er Ke Za Zhi. 2007年9卷6期587-90页
This study examined the effect of rapamycin, an inhibitor of mammalian target of rapamycin (mTOR), on eukaryotic initiation factor (eIF- 4E) expression in rat myocardial fibroblasts infected by Coxsackievirus B3 (CVB3) in order to identify the drug target for treatment of viral myocarditis.
830. [Effect and mechanism of apigenin on VEGF expression in human breast cancer cells].
To study the effects and mechanism of apigenin on the expression of vascular endothelial growth factor (VEGF) in human breast cancer MDA-MB-231 cells.
831. [Expression of acylation stimulating protein receptor (C5L2) in preadipocytes during differentiation and under stimulation of free fatty acids].
作者: Yu Wen.;Hong-Wei Wang.;Jing Wu.;Hui-Ling Lu.;Zhi Xia.;Katherine Cianflone.
来源: Zhonghua Yi Xue Za Zhi. 2007年87卷36期2571-4页
To observe the changes of expression of the acylation stimulating protein (ASP) functional receptor C5L2 during adipocytes differentiation, and to study the regulation of C5L2 by free fatty acid (FFA) in cultured adipocytes and preadipocytes.
832. [Influence of cyclosporine A on the mRNA and protein expression of major histocompatibility complexes I and II: experiment with rabbits].
To investigate the influence of cyclosporine A (CsA) on the mRNA and protein expression of major histocompatibility (MHC) I and II.
833. [Astragalus polysaccharides and astragalosides regulate cytokine secretion in LX-2 cell line].
作者: Shu-ping Li.;Xiao-yan Xu.;Zhen Sun.;Zhi Chen.
来源: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007年36卷6期543-8页
To investigate the anti-fibrosis mechanism of radix astragali through the observation on regulating cytokine secretion by astragalosides and astragalus polysaccharides in hepatic stellate cell line LX-2.
834. [Study on mechanisms of the expression regulation of interferon-induced gene RIG-G].
作者: Dong Li.;Shu Xiao.;Xiao-rong Pan.;Ye-jiang Lou.;Pei-min Jia.;Jian-hua Tong.
来源: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007年24卷6期625-8页
To investigate the molecular mechanisms of the expression regulation of retinoic acidinduced gene G (RIG-G) by interferon alpha (IFNalpha).
835. [Effects of ethyl acetate extract of Semen Hoveniae on liver microsomal cytochrome P450 isoenzyme in rat].
To investigate the effects of the ethyl acetate extract of Semen Hoveniae (ESH) on liver microsomal cytochrome P450 isoenzyme in rats.
836. [The mechanism of and relationship between lipid metabolism genes expression and insulin resistance in high fat-fed mice].
作者: Xiu-Ping Bai.;Hong-Liang Li.;Wen-Ying Yang.;Jian-Zhong Xiao.;Bing Wang.;Rui-Qin Du.;Da-Jun Lou.
来源: Zhonghua Nei Ke Za Zhi. 2007年46卷9期751-4页
To observe the relationship between changes of genes expression related to lipid metabolism and insulin resistance induced by high fat diet in SD rats.
837. [Inhibition effects of compound leech eye drops on apoptosis of lens epithelial cells and expressions of Bcl-2 and Bax genes in rats].
作者: Xiu-rong Huang.;Ming-xin Qi.;Zhao-yang Wang.;Yi Chen.
来源: Zhong Xi Yi Jie He Xue Bao. 2007年5卷6期681-5页
To investigate the inhibition effects of compound leech eye drops (Co-SZ) on apoptosis of lens epithelial cells (LECs) induced by hydrogen peroxide (H2O2) and the expressions of apoptosis-related genes Bcl-2 and Bax in rats.
838. [Effects of arsenic trioxide on expressions of vascular endothelial growth factor and P-glycoprotein in multidrug resistant leukemia cell line K562/A02].
作者: Hong Liang.;Yu Zhang.;Jian-dong Zhang.;Jian Gu.;Li Ma.;Xiao-ling Wang.;Wei-gan Shen.
来源: Zhong Xi Yi Jie He Xue Bao. 2007年5卷6期647-50页
To investigate the effects of arsenic trioxide (ATO) on the expressions of vascular endothelial growth factor (VEGF) and P-glycoprotein (P-gp) in K562/A02 cells and to explore the correlation between VEGF and P-gp.
839. [Expression and gene mutation of cluster of differentiation 9 in lung cancer cells induced by mineral powder in Gejiu].
作者: Rui Liang.;Ke-wei Jin.;Zhi-qiang Wang.;Ji-wu Chang.;Fu-ling Ma.;Yi Wang.;Qian Gao.
来源: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007年25卷9期537-40页
To investigate the expression and gene mutation of cluster of differentiation 9 (CD9) in the pathway of the mineral powder induced malignant transformation in immortalized human bronchial epithelial cells (BEAS-2B) in Gejiu.
840. [Effects of volatie oil of Schizonepeta tenuifolia Briq herb and Saposhnikovia divaricata Schischke root on proinflammatory cytokine expression and regulation].
作者: Wei-hong Ge.;Jian-you Guo.;Ying-jun Shen.;Min-li Chen.;Sen-lin Shi.;Yu-huan Han.;Jie Lin.
来源: Zhongguo Zhong Yao Za Zhi. 2007年32卷17期1777-9页
To study the effects of volatie oil of Schizonepeta tenuifolia Briq herb and Saposhnikovia divaricata Schischke root (OSS) on proinflammatory cytokine expression and regulation in rats.
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