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3881. [Effect of bailong recipe on proliferation phenotype of human gastric carcinoma BGC82-3 cell line].
To observe the reversive effect of Composite Bailong recipe (BR), a preparation of Chinese herbal medicine, on proliferation phenotype of human gastric carcinoma BGC82-3 cell line.
3882. [Clinical study on treatment of rectal carcinoma with Chinese herbal medicine and high dose fluorouracil emulsion via rectal infusion].
To study the clinical significance of rectal infusion of Chinese herbal medicine (CHM) plus high dose fluorouracil emulsion in treating rectal carcinoma.
3883. [Study on antitumor activity and mechanism of Ganoderma polysaccharides B].
To study the antitumor activity and mechanism of Ganoderma polysaccharides (GL-B).
3884. [Comparison of stepwise and pulse induced cisplatin-resistant ovarian cancer cell sublines].
To investigate the mechanism responsible for acquired cisplatin resistance induced in human ovarian cancer cell lines by different methods.
3885. [Differential display of vincristine-resistant proteins in gastric cancer cell line SGC7901].
To find out new multidrug-resistant proteins in gastric cancer cells SGC7901 and to explain the new multidrug-resistant mechanism of gastric cancer cells.
3886. [The clinical effect of Tropisetron in the prevention of nausea and vomiting induced by anti-cancer drugs].
To compare the efficacy and adverse effects of Tropisetron with Kytril in the prevention of nausea and vomiting induced by anti-cancer drugs.
3887. [Docitaxol-induction apoptosis of osteosarcoma].
To study the growth inhibition and apoptosis induction effect of docitaxol on osteosarcoma cells.
3888. [Mechanisms of arsenic trioxide-induced apoptosis in myeloma cells].
To investigate the possible mechanisms of arsenic trioxide (As2O3)-induced apoptosis in multiple myeloma (MM) cell line, and the interactions between As2O3 and all-trans retinoic acid (ATRA) or interferon(IFN)-alpha.
3889. [A comparative clinical study of carboplatin solution and carboplatin powder].
To observe the efficacy and side effects of carboplatin solution in comparison with carboplatin powder.
3890. [Mobilization of autologous peripheral blood stem cells by combined chemotherapy and rhG-CSF].
To study the effect of cyclophosphamide (CTX) combination chemotherapy and recombinant human granulocyte colony-stimulating factor (rhG-CSF) on autologous peripheral blood stem cells (APBSC) mobilization.
3891. [Clinical study of topotecan in the treatment of small cell lung cancer and recurrent ovarian cancer].
To evaluate the effect and adverse reaction of China made topotecan in the treatment of small-cell lung cancer (ACLC) and recurrent ovarian cancer (OV).
3892. [Investigation on the relationship between MDR and expression of N-glycosphingolipids in vincristine resistant KBv200 cell line].
To study the relationship between MDR and expression of N-glycosphingolipids (H-GSLs) in tumor cells.
3893. [Effects of hexamethylene bisacetamide on in vitro adhesion, motility and invasion of human mucoepidermoid carcinoma cell line MEC-1].
To investigate the effects of hexamethylene bisacetamide (HMBA) on the in vitro adhesion, motility and invasion of human mucoepidermoid carcinoma cell line MEC-1.
3894. [Clinical implication of apoptosis of breast cancer induced by preoperative chemotherapy].
To investigate whether apoptosis could be induced by preoperative chemotherapy in breast cancer patients, and determine if it is correlated with clinical response and patients' survival.
3895. [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine].
O6-alkylguanine-DNA alkyltransferase (O6-AGT), capable of repairing DNA damage, is responsible for tumor cell resistance to nitrosourea. While O6-benzylguanine as a selective inhibitor of AGT helps reverse drug resistance, it would aggravate myelo-suppression. This investigation is to generate AGT mutant and see if it would confer resistance to O6-benzylguanine-induced inhibition but leave its alkyltransferase activity intact.
3896. [The effects of RA538 and antisense c-myc on cervical cancer cell lines with high expression of bcl-2 gene].
To study the effects of recombinant adenovirus with RA538 or antisense c-myc insert on cervical cancer cell lines with high expression of bcl-2 gene.
3897. [Bcl-2 antisense oligodeoxyribonucleotide increases apoptosis of lung carcinoma cells induced by cisplatin].
To study the effect of antisense oligodeoxyribonucleotide (ODN) to apoptotic suppress gene bcl-2 on apoptosis of lung carcinoma cells induced by cisplatin.
3898. [Functional status of p53 and chemosensitivity of colon cancer cell lines].
To study the functional status of tumor suppressor gene p53 in relation to chemotherapeutic sensitivity in colon cancer cell lines.
3899. [Development of drug resistance and alteration of cell cycle in lung cancer: a flow cytometric study].
To study the relationship between the expression of multidrug resistance-associated protein (MRP) and P-glycoprotein (P-gp) and alteration of cell cycle during the process of drug resistance in lung cancer.
3900. [Genistein exerts multiple suppressive effects on human breast carcinoma cells].
To study the suppressive effects of genistein on progression of breast carcinoma.
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