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3561. [Experimental study on apoptosis induced by ursolic acid isolated from asparagus in HL-60 cells].
To study the inhibitory effect of ursolic acid isolated from Asparagus on the proliferation of HL-60 cells.
3562. [Study on preventive and therapeutic effect of radix salviae miltiorrhizae on recurrence and metastasis of liver cancer].
To study the inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on adhesive and invasive ability of SMMC-7721 liver cancer cells, and on the metastasis and recurrence on post-hepatectomy liver cancer in nude mice.
3563. [Cell differentiation and apoptosis of tumor cells].3564. [Review on experimental studies of Chinese drugs in antagonizing bone marrow inhibition caused by chemicals].3565. [Ailing No. I in treating 62 cases of acute promyelocytic leukemia].
To obtain further knowledge on the effect, mechanism and toxic side-effect of Ailing No. I (AL), a preparation of As2O3, in treating acute promyelocytic leukemia (APL).
3566. [Effect of bailong recipe on proliferation phenotype of human gastric carcinoma BGC82-3 cell line].
To observe the reversive effect of Composite Bailong recipe (BR), a preparation of Chinese herbal medicine, on proliferation phenotype of human gastric carcinoma BGC82-3 cell line.
3567. [Study on antitumor activity and mechanism of Ganoderma polysaccharides B].
To study the antitumor activity and mechanism of Ganoderma polysaccharides (GL-B).
3568. [Comparison of stepwise and pulse induced cisplatin-resistant ovarian cancer cell sublines].
To investigate the mechanism responsible for acquired cisplatin resistance induced in human ovarian cancer cell lines by different methods.
3569. [Differential display of vincristine-resistant proteins in gastric cancer cell line SGC7901].
To find out new multidrug-resistant proteins in gastric cancer cells SGC7901 and to explain the new multidrug-resistant mechanism of gastric cancer cells.
3570. [The clinical effect of Tropisetron in the prevention of nausea and vomiting induced by anti-cancer drugs].
To compare the efficacy and adverse effects of Tropisetron with Kytril in the prevention of nausea and vomiting induced by anti-cancer drugs.
3571. [Docitaxol-induction apoptosis of osteosarcoma].
To study the growth inhibition and apoptosis induction effect of docitaxol on osteosarcoma cells.
3572. [Mechanisms of arsenic trioxide-induced apoptosis in myeloma cells].
To investigate the possible mechanisms of arsenic trioxide (As2O3)-induced apoptosis in multiple myeloma (MM) cell line, and the interactions between As2O3 and all-trans retinoic acid (ATRA) or interferon(IFN)-alpha.
3573. [A comparative clinical study of carboplatin solution and carboplatin powder].
To observe the efficacy and side effects of carboplatin solution in comparison with carboplatin powder.
3574. [Mobilization of autologous peripheral blood stem cells by combined chemotherapy and rhG-CSF].
To study the effect of cyclophosphamide (CTX) combination chemotherapy and recombinant human granulocyte colony-stimulating factor (rhG-CSF) on autologous peripheral blood stem cells (APBSC) mobilization.
3575. [Clinical study of topotecan in the treatment of small cell lung cancer and recurrent ovarian cancer].
To evaluate the effect and adverse reaction of China made topotecan in the treatment of small-cell lung cancer (ACLC) and recurrent ovarian cancer (OV).
3576. [Investigation on the relationship between MDR and expression of N-glycosphingolipids in vincristine resistant KBv200 cell line].
To study the relationship between MDR and expression of N-glycosphingolipids (H-GSLs) in tumor cells.
3577. [Effects of hexamethylene bisacetamide on in vitro adhesion, motility and invasion of human mucoepidermoid carcinoma cell line MEC-1].
To investigate the effects of hexamethylene bisacetamide (HMBA) on the in vitro adhesion, motility and invasion of human mucoepidermoid carcinoma cell line MEC-1.
3578. [Clinical implication of apoptosis of breast cancer induced by preoperative chemotherapy].
To investigate whether apoptosis could be induced by preoperative chemotherapy in breast cancer patients, and determine if it is correlated with clinical response and patients' survival.
3579. [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine].
O6-alkylguanine-DNA alkyltransferase (O6-AGT), capable of repairing DNA damage, is responsible for tumor cell resistance to nitrosourea. While O6-benzylguanine as a selective inhibitor of AGT helps reverse drug resistance, it would aggravate myelo-suppression. This investigation is to generate AGT mutant and see if it would confer resistance to O6-benzylguanine-induced inhibition but leave its alkyltransferase activity intact.
3580. [The effects of RA538 and antisense c-myc on cervical cancer cell lines with high expression of bcl-2 gene].
To study the effects of recombinant adenovirus with RA538 or antisense c-myc insert on cervical cancer cell lines with high expression of bcl-2 gene.
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