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共有 1402 条符合本次的查询结果, 用时 2.567778 秒

261. [Effects of chlorogenic acid on the viability and HIF-1alpha mRNA expression of PC12 cells exposed to hypoxia].

作者: Xu Jia.;Zhong-Xue Fu.;Juan Yao.;Hui-Ping Ma.
来源: Zhong Yao Cai. 2013年36卷10期1644-7页
To investigate the effects of chlorogenic acid on the viability and HIF-1alpha mRNA expression of PC12 cells exposed to hypoxia.

262. [Experimental study on Dendrobium candidum polysaccharides on promotion of hair growth].

作者: Jian Chen.;Hui Qi.;Jin-Biao Li.;Yan-Qun Yi.;Dan Chen.;Xiao-Hong Hu.;Mei-Ling Wang.;Xing-Li Sun.;Xiao-Yong Wei.
来源: Zhongguo Zhong Yao Za Zhi. 2014年39卷2期291-5页
To observe the effect and mechanism of Dendrobium candidum polysaccharides (DCP) in promoting hair growth, in order to lay a foundation for the development and utilization of D. candidum.

263. [Expression analyses of BcUGT3 and BcUGT6, and their in vitro expression in Escherichia coli].

作者: Yun-Wen Tao.;Jie-Sen Xu.;Jing Sun.;Jian-He Wei.;Juan Liu.;Chun Sui.
来源: Zhongguo Zhong Yao Za Zhi. 2014年39卷2期185-91页
The tissue-specific and MeJA-induced transcriptional levels of BcUGT3 and BcUGT6 in Bupleurum chinense were analyzed in the present study. The transcriptional levels of BcUGT3 in root, leaf, flower and fruit were similar and they all were higher than those in stem. The transcriptional level of BcUGT6 was the highest in leaf and the lowest in flower among in all tested tissues. With non-treated adventitious roots as control, BcUGT6's transcriptional levels were elevated to nearly 2 folds for 2 h, 8 h, 24 h, 2 d and 4 d in MeJA-treated adventitious roots of B. chinense. It showed that the transcriptional level of BcUGT6 was slightly affected by MeJA. While, BcUGT3's transcriptional levels were gradually elevated, and till 4 d after MeJA treatment, the expression level was about 7 folds than that of non-treated control. Using pET-28a (+), the expressions of two genes was investigated. Induced by IPTG, the target proteins were expressed in E. coli and then purified. All the results obtained in the present study will be helpful for follow-up bio-function analysis of BcUGT3 and BcUGT6.

264. [Effect of chaperone-mediated autophagy in MPP(+) -induced SH-SY5Y cells and interventional effect of puerarin].

作者: Xun-Cui Wang.;Xiu Wang.;Qing-Lin Li.
来源: Zhongguo Zhong Yao Za Zhi. 2014年39卷1期106-12页
To study the protective effect of puerarin on MPP(+) -induced SH-SY5Y cells by chaperone-mediated autophagy (CMA).

265. [Atorvastatin inhibits cardiomyocyte apoptosis via down-cegulation the expression mitofusin 2 after myocardial ischemia/reperfusion injury in rats].

作者: Wei Zhou.;Ling Chen.;Manhua Chen.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷4期388-90页
To investigate the effects of atorvastatin (statin for short) on cell apoptosis and the expression of mitofusin 2 (Mfn2) after myocardial ischemia/reperfusion (I/R) injury in rats.

266. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2].

作者: Yang Zhang.;Zhiyi He.;Xuejiao Sun.;Zhanhua Li.;Lin Zhao.;Congzheng Mao.;Dongmei Huang.;Jianquan Zhang.;Xiaoning Zhong.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷4期384-7页
To investigate the effect of erythromycin (EM) on corticosteroid insensitivity of human THP-1 cells induced by cigarette smoke extract (CSE) and its mechanism.

267. [Protective effect of meloxicam against acute radiation-induced brain injury in rats].

作者: Lan Han.;Qinglan Ren.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷4期375-8页
OBJECTIVE To observe the protective effect of meloxicam against acute radiation-induced brain injury in rats.

268. [IL-17A promotes pulmonary inflammation in rats with pulmonary fibrosis induced by bleomycin].

作者: Chengliang Huang.;Yanyan Li.;Xianming Fan.;Yanmei Ma.;Ming Zhang.;Wenjun Wang.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷4期366-70页
To investigate the role of IL-17A in the development of pulmonary fibrosis in rats.

269. [Regulation of aquaporin 3 protein expression in amnion epithelial cells through cAMP-PKA signal pathway].

作者: Shengdi Ding.;Ying Hua.;Jun Wu.;Ailan Xie.;Xueqiong Zhu.
来源: Zhonghua Fu Chan Ke Za Zhi. 2014年49卷1期36-41页
To investigate the expression of aquaporins-3 (AQP3) in amniotic epithelial cells regulated by cyclic adenosine monophosphate-protein kinase A (cAMP-PKA) signal pathway and to explore the mechanisms of its expression.

270. [Effect of transforming growth factor beta3, bone morphogenetic protein 2, and dexamethasone on chondrogenic differentiation of rabbit synovial mesenchymal stem cells].

作者: Song Chen.;Peiliang Fu.;Ruijun Cong.;Haishan Wu.;Zhenyu Xu.
来源: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014年28卷1期92-9页
To study the effect of transforming growth factor beta3 (TGF-beta3), bone morphogenetic protein 2 (BMP-2), and dexamethasone (DEX) on the chondrogenic differentiation of rabbit synovial mesenchymal stem cells (SMSCs).

271. [Study on realgar nanoparticles inhibition of adenovirus replication at the gene level].

作者: Ming-Zhe Wang.;Wushouer Fuerhati.;Cheng-Xiang Wang.;Wen-Bo Xu.
来源: Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2013年27卷5期357-9页
Modeling HAdV-3 infect Hep-2 cells in vitro. The effect of realgar nanoparticles on the expression of HAdV-3 is detected by using fluorescent quantitative PCR.

272. [Effects of soothing liver and invigorating spleen recipes on NF-kappaB signal pathway related genes and proteins in primary hepatocytes of rats with NASH].

作者: Qin-He Yang.;Yong-Jian Xu.;Gao-Fei Feng.;Xue-Song Yang.;Li Han.;Yu-Pei Zhang.;Hong Wang.
来源: Zhong Yao Cai. 2013年36卷9期1469-76页
To observe the effects of soothing liver and invigorating spleen recipes on NF-kappaB signal pathway related genes and proteins in primary hepatocytes of rats with NASH.

273. [Acyldepsipeptide 1 induces apoptosis in renal cancer cells by down-regulation of Gli and Bcl-2 via SHH pathway].

作者: Shan Xu.;Chong DU.;Zhenkun Ma.;Yang Gao.;Qi Shi.;Xinyang Wang.;Hailong Zhang.;Dalin He.;Peng Guo.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷3期258-61, 265页
To investigate the effects of acyldepsipeptide 1 (ADEP1) on renal cancer cell apoptosis and on the expressions of SHH signaling pathway related protein Gli-1 and Bcl-2.

274. [Role of the expression level of Nrf2 in predicting response of EGFR-TKIs in lung adenocarcinoma patients with EGFR gene mutations].

作者: Xiang Zhu.;Li Liang.;Chen Liu.;Wencheng Yin.;Sen Chen.;Baoshan Cao.
来源: Zhongguo Fei Ai Za Zhi. 2014年17卷2期155-62页
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have become first-line treatment drugs for lung adenocarcinoma patients with EGFR gene mutations. Significant interindividual variations in response rate, progression-free survival (PFS), and overall survival (OS) have been observed. The expression level of nuclear factor erythroid-2-related factor 2 (Nrf2) is related to chemoresistance against platinum drugs. Nrf2 overexpression can inhibit the sensitivity of EGFR-TKIs in cells with EGFR-sensitive mutations. The aim of this study is to investigate the protein expression level of Nrf2 in lung adenocarcinoma patients with EGFR gene mutations and to elucidate the correlation between Nrf2 expression and response rate of first-line EGFR-TKIs, as well as PFS and OS.

275. [The effect and mechanism of vinorelbine on cisplatin resistance of human lung cancer cell line A549/DDP].

作者: Chunsheng Qi.;Sen Gao.;Huiqiang Li.;Weizhen Gao.
来源: Zhongguo Fei Ai Za Zhi. 2014年17卷2期148-54页
Drug resistance is a major obstacle on lung cancer treatment and Vinorelbine is an effective drug to inhibition of tumor proliferation and metastasis. In this study, we investigated the effect and mechanism of Vinorelbine on reversing the cisplatin resistance of human lung cancer A549/DDP cell line.

276. [Down-regulatory effects of budesonide on expression of STAT6 and ORMDL3 in lung tissues of asthmatic mice].

作者: Li-Ping Zou.;Xi Zhang.;Yan Zhang.;Xiu-Juan Xu.;Tie-Feng Wang.
来源: Zhongguo Dang Dai Er Ke Za Zhi. 2014年16卷2期198-202页
To investigate the roles of signal transduction and activator of transcription 6 (STAT6) and orosomucoid 1-like 3 (ORMDL3) in airway remodeling among asthmatic mice and to observe the effects of budesonide (BUD) on their expression.

277. [Study on the inhibiting effects of equol on MCF-7 cells proliferation and its molecular mechanisms].

作者: Meng Wang.;Guofeng Ren.
来源: Wei Sheng Yan Jiu. 2014年43卷1期11-5页
To investigate the proliferation inhibition effects of equol on human breast cancer cell line MCF-7 and explore its molecular mechanisms.

278. [Effect of water extracts from duhuo jisheng decoction on expression of chondrocyte G1 phase regulator mRNA].

作者: Jia-Shou Chen.;Xi-Hai Li.;Hui-Ting Li.;Xia-Ping Weng.;Hui-Feng Xu.;Hong-Zhi Ye.;Xian-Xiang Liu.
来源: Zhongguo Zhong Yao Za Zhi. 2013年38卷22期3949-52页
To investigate the effect of water extracts from Duhuo Jisheng decoction on chondrocyte G1 phase.

279. [Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice].

作者: Zong-mei Zhang.;Pan Gu.;Xiang-hua Yi.;Xia Fang.;Yu Zeng.;Su-xia Zhang.;Xu-you Zhu.;Yu-dong Zhang.;Jun Gu.;Wei-zhe Qiu.;Long Zhang.
来源: Zhonghua Jie He He Hu Xi Za Zhi. 2013年36卷11期814-20页
To observe the effects of 1, 25(OH)2D3 on bleomycin-induced pulmonary fibrosis in mice and to explore its mechanisms.

280. [Dexamethasone induces PC12 cell apoptosis by down-regulating glucose uptake].

作者: Xiaoying Liu.;Yanping Wang.;Chen Qiu.;Qing Zhou.;Zhou Chen.;Libin Liu.
来源: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014年30卷2期160-3页
To observe the effects of dexamethasone (DEX) on rat PC12 chromaffin tumor cells and glucose uptake.
共有 1402 条符合本次的查询结果, 用时 2.567778 秒