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141. Serum prealbumin is an independent predictor of mortality in systemic sclerosis outpatients.
作者: Veronica Codullo.;Emanuele Cereda.;Catherine Klersy.;Ilaria Cavazzana.;Claudia Alpini.;Chiara Bonardi.;Annalisa Turri.;Franco Franceschini.;Riccardo Caccialanza.;Carlomaurizio Montecucco.;Roberto Caporali.
来源: Rheumatology (Oxford). 2016年55卷2期315-9页
Serum prealbumin is a recognized marker of malnutrition, but its role in the prognosis of patients with SSc has not yet been investigated. The aim of the present multicentre prospective study was to investigate the association between prealbumin and mortality, independent of clinical features, in a cohort of SSc outpatients.
142. Autologous adipose-derived stromal vascular fraction in patients with systemic sclerosis: 12-month follow-up.
作者: Perrine Guillaume-Jugnot.;Aurélie Daumas.;Jérémy Magalon.;Elisabeth Jouve.;Pierre-Sébastien Nguyen.;Romain Truillet.;Stéphanie Mallet.;Dominique Casanova.;Laurent Giraudo.;Julie Veran.;Françoise Dignat-George.;Florence Sabatier.;Guy Magalon.;Brigitte Granel.
来源: Rheumatology (Oxford). 2016年55卷2期301-6页
Impaired hand function greatly contributes to disability and reduced quality of life in SSc patients. Autologous adipose-derived stromal vascular fraction (ADSVF) is recognized as an easily accessible source of regenerative cells. We reported positive 6-month safety and efficacy results from an open-label clinical trial assessing s.c. injection of autologous ADSVF into the fingers in SSc patients. The objective of this report is to describe the effects at 12 months.
143. A high body mass index is associated with reduced risk of rheumatoid arthritis in men, but not in women.
作者: Carl Turesson.;Ulf Bergström.;Mitra Pikwer.;Jan-Åke Nilsson.;Lennart T H Jacobsson.
来源: Rheumatology (Oxford). 2016年55卷2期307-14页
To investigate the impact of overweight and obesity on the risk of RA.
144. Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study.
作者: Arsène Mekinian.;Eric Grignano.;Thorsten Braun.;Olivier Decaux.;Eric Liozon.;Nathalie Costedoat-Chalumeau.;Jean-Emmanuel Kahn.;Mohammed Hamidou.;Sophie Park.;Xavier Puéchal.;Eric Toussirot.;Géraldine Falgarone.;David Launay.;Nathalie Morel.;Sébastien Trouiller.;Alexis Mathian.;Bruno Gombert.;Yoland Schoindre.;Bertrand Lioger.;Benoit De Wazieres.;Zahir Amoura.;Anne-Laure Buchdaul.;Sophie Georgin-Lavialle.;Jérémie Dion.;Serge Madaule.;Loïc Raffray.;Pascal Cathebras.;Jean Charles Piette.;Christian Rose.;Jean Marc Ziza.;Olivier Lortholary.;Francois Montestruc.;Mohammed Omouri.;Guillaume Denis.;Julien Rossignol.;Stanislas Nimubona.;Lionel Adès.;Claude Gardin.;Pierre Fenaux.;Olivier Fain.
来源: Rheumatology (Oxford). 2016年55卷2期291-300页
We describe myelodysplastic syndrome (MDS)-associated systemic inflammatory and autoimmune diseases (SIADs), their treatments and outcomes and the impact of SIADs on overall survival in a French multicentre retrospective study.
145. Symptoms of depression and anxiety predict treatment response and long-term physical health outcomes in rheumatoid arthritis: secondary analysis of a randomized controlled trial.
作者: Faith Matcham.;Sam Norton.;David L Scott.;Sophia Steer.;Matthew Hotopf.
来源: Rheumatology (Oxford). 2016年55卷2期268-78页
The aim of this analysis is to examine the longitudinal impact of symptoms of depression/anxiety on treatment response, long-term disease activity and physical disability in RA.
146. Inefficacy of ultrasound-guided local injections of autologous conditioned plasma for recent epicondylitis: results of a double-blind placebo-controlled randomized clinical trial with one-year follow-up.
作者: Bernard Montalvan.;Patrick Le Goux.;Shahnaz Klouche.;Delphine Borgel.;Philippe Hardy.;Maxime Breban.
来源: Rheumatology (Oxford). 2016年55卷2期279-85页
The aim was to assess the efficacy of two intra-tendinous injections of platelet-rich plasma (PRP) on epicondylitis of recent evolution (≤3 months).
147. Low rates of biologic-free clinical disease activity index remission maintenance after biologic disease-modifying anti-rheumatic drug discontinuation while in remission in a Japanese multicentre rheumatoid arthritis registry.
作者: Kazuki Yoshida.;Mitsumasa Kishimoto.;Helga Radner.;Kazuo Matsui.;Masato Okada.;Yukihiko Saeki.;Daniel H Solomon.;Shigeto Tohma.
来源: Rheumatology (Oxford). 2016年55卷2期286-90页
To examine in detail the outcomes of biologic DMARD (bDMARD) discontinuation while in remission occurring in daily clinical practice settings. We examined a multicentre longitudinal registry of RA patients.
148. Decreased levels of regulatory B cells in patients with systemic sclerosis: association with autoantibody production and disease activity.
作者: Takashi Matsushita.;Yasuhito Hamaguchi.;Minoru Hasegawa.;Kazuhiko Takehara.;Manabu Fujimoto.
来源: Rheumatology (Oxford). 2016年55卷2期263-7页
B cell abnormalities characterized by autoantibody production and polyclonal B cell activation play an important role in the pathogenesis of SSc. IL-10 producing regulatory B (Breg) cells also play an important role in the negative immune response. We identified a human Breg cell subset that was predominantly found within the CD24(hi)CD27(+) B cell subpopulation. However, the role of Breg cells in SSc remains unknown. The aim of this study was to investigate the clinical association of Breg cells in SSc patients.
150. Recent insights into the role of autophagy in the pathogenesis of rheumatoid arthritis.
Autophagy appears to play a dual role in eukaryotic cells. It manifests cytoprotective effects through the regulation of catabolic processes and the clearance of pathogens; however, a correlation between autophagy and the pathogenesis of autoimmune/autoinflammatory conditions has recently been described. Autophagy has emerged as a mediator in the pathogenesis of RA. Autophagy may regulate apoptosis resistance and hyperplasia in synovial fibroblasts, promote osteoclastogenesis and stimulate osteoclast-mediated bone resorption through the delivery of citrullinated peptides to MHC compartments, which results in the activation of the innate and adaptive immune response, thereby resulting in RA. Given the likely importance of autophagy in the pathogenesis of RA, here we reviewed the detailed mechanisms concerning the pathogenicity of autophagy and autophagy proteins in RA.
156. The frequency and outcome of lupus nephritis: results from an international inception cohort study.
作者: John G Hanly.;Aidan G O'Keeffe.;Li Su.;Murray B Urowitz.;Juanita Romero-Diaz.;Caroline Gordon.;Sang-Cheol Bae.;Sasha Bernatsky.;Ann E Clarke.;Daniel J Wallace.;Joan T Merrill.;David A Isenberg.;Anisur Rahman.;Ellen M Ginzler.;Paul Fortin.;Dafna D Gladman.;Jorge Sanchez-Guerrero.;Michelle Petri.;Ian N Bruce.;Mary Anne Dooley.;Rosalind Ramsey-Goldman.;Cynthia Aranow.;Graciela S Alarcón.;Barri J Fessler.;Kristjan Steinsson.;Ola Nived.;Gunnar K Sturfelt.;Susan Manzi.;Munther A Khamashta.;Ronald F van Vollenhoven.;Asad A Zoma.;Manuel Ramos-Casals.;Guillermo Ruiz-Irastorza.;S Sam Lim.;Thomas Stoll.;Murat Inanc.;Kenneth C Kalunian.;Diane L Kamen.;Peter Maddison.;Christine A Peschken.;Soren Jacobsen.;Anca Askanase.;Chris Theriault.;Kara Thompson.;Vernon Farewell.
来源: Rheumatology (Oxford). 2016年55卷2期252-62页
To determine nephritis outcomes in a prospective multi-ethnic/racial SLE inception cohort.
158. Salivary gland ultrasonography as a primary imaging tool for predicting efficacy of xerostomia treatment in patients with Sjögren's syndrome.
作者: Yukinori Takagi.;Misa Sumi.;Hideki Nakamura.;Shuntaro Sato.;Atsushi Kawakami.;Takashi Nakamura.
来源: Rheumatology (Oxford). 2016年55卷2期237-45页
To evaluate ultrasonography (US) grading of salivary gland disease as a predictor of treatment efficacy for impaired salivary function in xerostomia patients with or without Sjögren's syndrome (SS).
159. Suppression of inflammatory disease activity in rheumatoid arthritis is associated with improvements in retinal microvascular health.
作者: John Hsing-Yih Moi.;Lauren A B Hodgson.;Ian P Wicks.;Tien Yin Wong.;Sharon Van Doornum.
来源: Rheumatology (Oxford). 2016年55卷2期246-51页
To investigate the effect of suppressing inflammation on retinal microvascular health in patients with RA.
160. Comment on: Intravenous neridronate in the treatment of acute painful knee osteoarthritis: a randomized controlled study: reply.
作者: Massimo Varenna.;Francesca Zucchi.;Simonetta Failoni.;Andrea Becciolini.;Massimo Berruto.
来源: Rheumatology (Oxford). 2015年54卷11期2117-8页 |