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1207. Polypharmacy in the Aging Patient: A Review of Glycemic Control in Older Adults With Type 2 Diabetes.
There is substantial uncertainty about optimal glycemic control in older adults with type 2 diabetes mellitus.
1208. Association Between Hypertensive Disorders of Pregnancy and Later Risk of Cardiomyopathy.
作者: Ida Behrens.;Saima Basit.;Jacob Alexander Lykke.;Mattis Flyvholm Ranthe.;Jan Wohlfahrt.;Henning Bundgaard.;Mads Melbye.;Heather A Boyd.
来源: JAMA. 2016年315卷10期1026-33页
Women with hypertensive disorders of pregnancy, preeclampsia in particular, have an increased risk of cardiomyopathy during the peripartum period. Whether hypertensive disorders of pregnancy are also associated with cardiomyopathy later in life is unknown.
1209. Clinical Risk Score for Persistent Postconcussion Symptoms Among Children With Acute Concussion in the ED.
作者: Roger Zemek.;Nick Barrowman.;Stephen B Freedman.;Jocelyn Gravel.;Isabelle Gagnon.;Candice McGahern.;Mary Aglipay.;Gurinder Sangha.;Kathy Boutis.;Darcy Beer.;William Craig.;Emma Burns.;Ken J Farion.;Angelo Mikrogianakis.;Karen Barlow.;Alexander S Dubrovsky.;Willem Meeuwisse.;Gerard Gioia.;William P Meehan.;Miriam H Beauchamp.;Yael Kamil.;Anne M Grool.;Blaine Hoshizaki.;Peter Anderson.;Brian L Brooks.;Keith Owen Yeates.;Michael Vassilyadi.;Terry Klassen.;Michelle Keightley.;Lawrence Richer.;Carol DeMatteo.;Martin H Osmond.; .
来源: JAMA. 2016年315卷10期1014-25页
Approximately one-third of children experiencing acute concussion experience ongoing somatic, cognitive, and psychological or behavioral symptoms, referred to as persistent postconcussion symptoms (PPCS). However, validated and pragmatic tools enabling clinicians to identify patients at risk for PPCS do not exist.
1210. Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial.
作者: Xingzhong Jin.;Graeme Jones.;Flavia Cicuttini.;Anita Wluka.;Zhaohua Zhu.;Weiyu Han.;Benny Antony.;Xia Wang.;Tania Winzenberg.;Leigh Blizzard.;Changhai Ding.
来源: JAMA. 2016年315卷10期1005-13页
Observational studies suggest that vitamin D supplementation is associated with benefits for knee osteoarthritis, but current trial evidence is contradictory.
1211. Effect of Naltrexone-Bupropion on Major Adverse Cardiovascular Events in Overweight and Obese Patients With Cardiovascular Risk Factors: A Randomized Clinical Trial.
作者: Steven E Nissen.;Kathy E Wolski.;Lisa Prcela.;Thomas Wadden.;John B Buse.;George Bakris.;Alfonso Perez.;Steven R Smith.
来源: JAMA. 2016年315卷10期990-1004页
Few cardiovascular outcomes trials have been conducted for obesity treatments. Withdrawal of 2 marketed drugs has resulted in controversy about the cardiovascular safety of obesity agents.
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