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1183. CDC Guideline for Prescribing Opioids for Chronic Pain--United States, 2016.
Primary care clinicians find managing chronic pain challenging. Evidence of long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious risks, including opioid use disorder and overdose.
1186. Effect of Noninvasive Ventilation on Tracheal Reintubation Among Patients With Hypoxemic Respiratory Failure Following Abdominal Surgery: A Randomized Clinical Trial.
作者: Samir Jaber.;Thomas Lescot.;Emmanuel Futier.;Catherine Paugam-Burtz.;Philippe Seguin.;Martine Ferrandiere.;Sigismond Lasocki.;Olivier Mimoz.;Baptiste Hengy.;Antoine Sannini.;Julien Pottecher.;Paër-Sélim Abback.;Beatrice Riu.;Fouad Belafia.;Jean-Michel Constantin.;Elodie Masseret.;Marc Beaussier.;Daniel Verzilli.;Audrey De Jong.;Gerald Chanques.;Laurent Brochard.;Nicolas Molinari.; .
来源: JAMA. 2016年315卷13期1345-53页
It has not been established whether noninvasive ventilation (NIV) reduces the need for invasive mechanical ventilation in patients who develop hypoxemic acute respiratory failure after abdominal surgery.
1187. Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis.
作者: Lonneke A van Vught.;Peter M C Klein Klouwenberg.;Cristian Spitoni.;Brendon P Scicluna.;Maryse A Wiewel.;Janneke Horn.;Marcus J Schultz.;Peter Nürnberg.;Marc J M Bonten.;Olaf L Cremer.;Tom van der Poll.; .
来源: JAMA. 2016年315卷14期1469-79页
Sepsis is considered to induce immune suppression, leading to increased susceptibility to secondary infections with associated late mortality.
1188. Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial.
作者: Michael C Reade.;Glenn M Eastwood.;Rinaldo Bellomo.;Michael Bailey.;Andrew Bersten.;Benjamin Cheung.;Andrew Davies.;Anthony Delaney.;Angaj Ghosh.;Frank van Haren.;Nerina Harley.;David Knight.;Shay McGuiness.;John Mulder.;Steve O'Donoghue.;Nicholas Simpson.;Paul Young.; .; .
来源: JAMA. 2016年315卷14期1460-8页
Effective therapy has not been established for patients with agitated delirium receiving mechanical ventilation.
1189. Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial.
作者: Gonzalo Hernández.;Concepción Vaquero.;Paloma González.;Carles Subira.;Fernando Frutos-Vivar.;Gemma Rialp.;Cesar Laborda.;Laura Colinas.;Rafael Cuena.;Rafael Fernández.
来源: JAMA. 2016年315卷13期1354-61页
Studies of mechanically ventilated critically ill patients that combine populations that are at high and low risk for reintubation suggest that conditioned high-flow nasal cannula oxygen therapy after extubation improves oxygenation compared with conventional oxygen therapy. However, conclusive data about reintubation are lacking.
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