当前位置: 首页 >> 检索结果
921. Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings.
作者: Charlotte R Hedin.;Neil E McCarthy.;Petra Louis.;Freda M Farquharson.;Sara McCartney.;Kirstin Taylor.;Natalie J Prescott.;Trevor Murrells.;Andrew J Stagg.;Kevin Whelan.;James O Lindsay.
来源: Gut. 2014年63卷10期1578-86页
Crohn's disease (CD) is associated with intestinal dysbiosis, altered blood T cell populations, elevated faecal calprotectin (FC) and increased intestinal permeability (IP). CD-associated features present in siblings (increased risk of CD) but not in healthy controls, provide insight into early CD pathogenesis. We aimed to (1) Delineate the genetic, immune and microbiological profile of patients with CD, their siblings and controls and (2) Determine which factors discriminate between groups.
924. Long-term recurrence of neoplasia and Barrett's epithelium after complete endoscopic resection.
作者: Mario Anders.;Christina Bähr.;Muhammad Abbas El-Masry.;Andreas H Marx.;Martin Koch.;Stefan Seewald.;Guido Schachschal.;Andreas Adler.;Nib Soehendra.;Jakob Izbicki.;Peter Neuhaus.;Heiko Pohl.;Thomas Rösch.
来源: Gut. 2014年63卷10期1535-43页
Current endoscopic therapy for neoplastic Barrett's oesophagus (BO) consists of complete resection/ablation of all Barrett's tissue including neoplastic lesions. Recurrence seems to be frequent after thermal therapy, such as radiofrequency ablation.
925. Source of dietary fibre and diverticular disease incidence: a prospective study of UK women.
作者: Francesca L Crowe.;Angela Balkwill.;Benjamin J Cairns.;Paul N Appleby.;Jane Green.;Gillian K Reeves.;Timothy J Key.;Valerie Beral.; .; .
来源: Gut. 2014年63卷9期1450-6页
Previous prospective studies have found the incidence of intestinal diverticular disease decreased with increasing intakes of dietary fibre, but associations by the fibre source are less well characterised. We assessed these associations in a large UK prospective study of middle-aged women.
926. A score to estimate the likelihood of detecting advanced colorectal neoplasia at colonoscopy.
作者: Michal F Kaminski.;Marcin Polkowski.;Ewa Kraszewska.;Maciej Rupinski.;Eugeniusz Butruk.;Jaroslaw Regula.
来源: Gut. 2014年63卷7期1112-9页
This study aimed to develop and validate a model to estimate the likelihood of detecting advanced colorectal neoplasia in Caucasian patients.
930. PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis.
作者: Xuehui Hong.;Ruipeng Song.;Huiwen Song.;Tongsen Zheng.;Jiabei Wang.;Yingjian Liang.;Shuyi Qi.;Zhaoyang Lu.;Xuan Song.;Hongchi Jiang.;Lianxin Liu.;Zhiyong Zhang.
来源: Gut. 2014年63卷10期1635-47页
Mounting epidemiological evidence supports a role for phosphatase and tensin homologue (PTEN)-T cell leukaemia 1 (Tcl1) signalling deregulation in hepatocarcinogenesis.
932. A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea.
作者: Klara Garsed.;Julia Chernova.;Margaret Hastings.;Ching Lam.;Luca Marciani.;Gulzar Singh.;Amanda Henry.;Ian Hall.;Peter Whorwell.;Robin Spiller.
来源: Gut. 2014年63卷10期1617-25页
Irritable bowel syndrome with diarrhoea (IBS-D) is particularly debilitating due to urgency and episodic incontinence. Some 5-hydroxytryptamine 3 (5-HT3) receptor antagonists (5-HT3RAs) have proven effective but have serious side effects. Ondansetron, also a 5-HT3RA, has been widely used as an antiemetic with an excellent safety record for over two decades. Our aim was to assess its effectiveness in IBS-D.
935. Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study.
作者: Kentaro Sugano.;Myung-Gyu Choi.;Jaw-Town Lin.;Shinya Goto.;Yasushi Okada.;Yoshikazu Kinoshita.;Hiroto Miwa.;Chern-En Chiang.;Tsutomu Chiba.;Masatsugu Hori.;Yasushi Fukushima.;Hyun-Soo Kim.;Chi-Yang Chang.;Masataka Date.; .
来源: Gut. 2014年63卷7期1061-8页
To evaluate if esomeprazole prevents recurrent peptic ulcer in adult patients with a history of peptic ulcer receiving low-dose acetylsalicylic acid (ASA, aspirin) for cardiovascular protection in East Asia.
936. Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome.
作者: Jonna Jalanka-Tuovinen.;Jarkko Salojärvi.;Anne Salonen.;Outi Immonen.;Klara Garsed.;Fiona M Kelly.;Abed Zaitoun.;Airi Palva.;Robin C Spiller.;Willem M de Vos.
来源: Gut. 2014年63卷11期1737-45页
About 10% of patients with IBS report the start of the syndrome after infectious enteritis. The clinical features of postinfectious IBS (PI-IBS) resemble those of diarrhoea-predominant IBS (IBS-D). While altered faecal microbiota has been identified in other IBS subtypes, composition of the microbiota in patients with PI-IBS remains uncharacterised.
939. Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial.
作者: Kevin S H Liu.;Ivan F N Hung.;W K Walter Seto.;Teresa Tong.;Axel S J Hsu.;Frank Y F Lam.;David Y K But.;S Y Wong.;Wai K Leung.
来源: Gut. 2014年63卷9期1410-5页
Treatments with sequential therapy (SEQ) or bismuth quadruple (QUAD) therapy have been proposed as empirical firstline regimens for Helicobacter pylori. We compared the efficacy and tolerability of 10 day SEQ with 10 day modified QUAD as both firstline and secondline treatments for H pylori in a randomised crossover study.
|