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724. Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2016 Recommendations of the International Antiviral Society-USA Panel.
作者: Huldrych F Günthard.;Michael S Saag.;Constance A Benson.;Carlos del Rio.;Joseph J Eron.;Joel E Gallant.;Jennifer F Hoy.;Michael J Mugavero.;Paul E Sax.;Melanie A Thompson.;Rajesh T Gandhi.;Raphael J Landovitz.;Davey M Smith.;Donna M Jacobsen.;Paul A Volberding.
来源: JAMA. 2016年316卷2期191-210页
New data and therapeutic options warrant updated recommendations for the use of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults.
725. Association of Medical Male Circumcision and Antiretroviral Therapy Scale-up With Community HIV Incidence in Rakai, Uganda.
作者: Xiangrong Kong.;Godfrey Kigozi.;Joseph Ssekasanvu.;Fred Nalugoda.;Gertrude Nakigozi.;Anthony Ndyanabo.;Tom Lutalo.;Steven J Reynolds.;Robert Ssekubugu.;Joseph Kagaayi.;Eva Bugos.;Larry W Chang.;Pilgrim Nanlesta.;Grabowski Mary.;Amanda Berman.;Thomas C Quinn.;David Serwadda.;Maria J Wawer.;Ronald H Gray.
来源: JAMA. 2016年316卷2期182-90页
Medical male circumcision (MMC) and antiretroviral therapy (ART) are proven HIV prevention interventions, but there are limited data on the population-level effect of scale-up of these interventions in sub-Saharan Africa. Such evaluation is important for planning and resource allocation.
726. Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy.
作者: Alison J Rodger.;Valentina Cambiano.;Tina Bruun.;Pietro Vernazza.;Simon Collins.;Jan van Lunzen.;Giulio Maria Corbelli.;Vicente Estrada.;Anna Maria Geretti.;Apostolos Beloukas.;David Asboe.;Pompeyo Viciana.;Félix Gutiérrez.;Bonaventura Clotet.;Christian Pradier.;Jan Gerstoft.;Rainer Weber.;Katarina Westling.;Gilles Wandeler.;Jan M Prins.;Armin Rieger.;Marcel Stoeckle.;Tim Kümmerle.;Teresa Bini.;Adriana Ammassari.;Richard Gilson.;Ivanka Krznaric.;Matti Ristola.;Robert Zangerle.;Pia Handberg.;Antonio Antela.;Sris Allan.;Andrew N Phillips.;Jens Lundgren.; .
来源: JAMA. 2016年316卷2期171-81页
A key factor in assessing the effectiveness and cost-effectiveness of antiretroviral therapy (ART) as a prevention strategy is the absolute risk of HIV transmission through condomless sex with suppressed HIV-1 RNA viral load for both anal and vaginal sex.
727. Effect of Patient Navigation With or Without Financial Incentives on Viral Suppression Among Hospitalized Patients With HIV Infection and Substance Use: A Randomized Clinical Trial.
作者: Lisa R Metsch.;Daniel J Feaster.;Lauren Gooden.;Tim Matheson.;Maxine Stitzer.;Moupali Das.;Mamta K Jain.;Allan E Rodriguez.;Wendy S Armstrong.;Gregory M Lucas.;Ank E Nijhawan.;Mari-Lynn Drainoni.;Patricia Herrera.;Pamela Vergara-Rodriguez.;Jeffrey M Jacobson.;Michael J Mugavero.;Meg Sullivan.;Eric S Daar.;Deborah K McMahon.;David C Ferris.;Robert Lindblad.;Paul VanVeldhuisen.;Neal Oden.;Pedro C Castellón.;Susan Tross.;Louise F Haynes.;Antoine Douaihy.;James L Sorensen.;David S Metzger.;Raul N Mandler.;Grant N Colfax.;Carlos del Rio.
来源: JAMA. 2016年316卷2期156-70页
Substance use is a major driver of the HIV epidemic and is associated with poor HIV care outcomes. Patient navigation (care coordination with case management) and the use of financial incentives for achieving predetermined outcomes are interventions increasingly promoted to engage patients in substance use disorders treatment and HIV care, but there is little evidence for their efficacy in improving HIV-1 viral suppression rates.
736. United States Health Care Reform: Progress to Date and Next Steps.
The Affordable Care Act is the most important health care legislation enacted in the United States since the creation of Medicare and Medicaid in 1965. The law implemented comprehensive reforms designed to improve the accessibility, affordability, and quality of health care.
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