633. Association Between Off-site Central Monitoring Using Standardized Cardiac Telemetry and Clinical Outcomes Among Non-Critically Ill Patients.
作者: Daniel J Cantillon.;Molly Loy.;Alicia Burkle.;Shannon Pengel.;Deborah Brosovich.;Aaron Hamilton.;Umesh N Khot.;Bruce D Lindsay.
来源: JAMA. 2016年316卷5期519-24页
Telemetry alarms involving traditional on-site monitoring rarely alter management and often miss serious events, sometimes resulting in death. Poor patient selection contributes to a high alarm volume with low clinical yield.
634. Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial.
作者: Anthony C Gordon.;Alexina J Mason.;Neeraja Thirunavukkarasu.;Gavin D Perkins.;Maurizio Cecconi.;Magda Cepkova.;David G Pogson.;Hollmann D Aya.;Aisha Anjum.;Gregory J Frazier.;Shalini Santhakumaran.;Deborah Ashby.;Stephen J Brett.; .
来源: JAMA. 2016年316卷5期509-18页
Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative.
635. Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.
作者: Kenneth B Margulies.;Adrian F Hernandez.;Margaret M Redfield.;Michael M Givertz.;Guilherme H Oliveira.;Robert Cole.;Douglas L Mann.;David J Whellan.;Michael S Kiernan.;G Michael Felker.;Steven E McNulty.;Kevin J Anstrom.;Monica R Shah.;Eugene Braunwald.;Thomas P Cappola.; .
来源: JAMA. 2016年316卷5期500-8页
Abnormal cardiac metabolism contributes to the pathophysiology of advanced heart failure with reduced left ventricular ejection fraction (LVEF). Glucagon-like peptide 1 (GLP-1) agonists have shown cardioprotective effects in early clinical studies of patients with advanced heart failure, irrespective of type 2 diabetes status.
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