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501. Long-Term Outcomes of Patients With Recent-Onset Rheumatoid Arthritis After 10 Years of Tight Controlled Treatment: A Randomized Trial.
作者: Iris M Markusse.;Gülsah Akdemir.;Linda Dirven.;Yvonne P M Goekoop-Ruiterman.;Johannes H L M van Groenendael.;K Huub Han.;T H Esmeralda Molenaar.;Saskia Le Cessie.;Willem F Lems.;Peter A H M van der Lubbe.;Pit J S M Kerstens.;André J Peeters.;H Karel Ronday.;Peter B J de Sonnaville.;Irene Speyer.;Theo Stijnen.;Saskia Ten Wolde.;Tom W J Huizinga.;Cornelia F Allaart.
来源: Ann Intern Med. 2016年164卷8期523-31页
Treat-to-target therapy is effective for patients with rheumatoid arthritis (RA), but long-term results of continued targeted treatment are lacking.
503. Importation, Antibiotics, and Clostridium difficile Infection in Veteran Long-Term Care: A Multilevel Case-Control Study.
作者: Kevin A Brown.;Makoto Jones.;Nick Daneman.;Frederick R Adler.;Vanessa Stevens.;Kevin E Nechodom.;Matthew B Goetz.;Matthew H Samore.;Jeanmarie Mayer.
来源: Ann Intern Med. 2016年164卷12期787-94页
Although clinical factors affecting a person's susceptibility to Clostridium difficile infection are well-understood, little is known about what drives differences in incidence across long-term care settings.
504. Network Meta-analysis for Clinical Practice Guidelines: A Case Study on First-Line Medical Therapies for Primary Open-Angle Glaucoma.
作者: Benjamin Rouse.;Andrea Cipriani.;Qiyuan Shi.;Anne L Coleman.;Kay Dickersin.;Tianjing Li.
来源: Ann Intern Med. 2016年164卷10期674-82页
Network meta-analysis compares multiple treatment options for the same condition and may be useful for developing clinical practice guidelines.
505. Early Coverage, Access, Utilization, and Health Effects Associated With the Affordable Care Act Medicaid Expansions: A Quasi-experimental Study.
In 2014, only 26 states and the District of Columbia chose to implement the Patient Protection and Affordable Care Act (ACA) Medicaid expansions for low-income adults.
506. Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: A Systematic Review and Meta-analysis.
作者: Nisa M Maruthur.;Eva Tseng.;Susan Hutfless.;Lisa M Wilson.;Catalina Suarez-Cuervo.;Zackary Berger.;Yue Chu.;Emmanuel Iyoha.;Jodi B Segal.;Shari Bolen.
来源: Ann Intern Med. 2016年164卷11期740-51页
Clinicians and patients need updated evidence on the comparative effectiveness and safety of diabetes medications to make informed treatment choices.
510. Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement.
Update of the 2009 USPSTF recommendation on aspirin use to prevent cardiovascular disease (CVD) events and the 2007 recommendation on aspirin and nonsteroidal anti-inflammatory drug use to prevent colorectal cancer (CRC).
511. Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force.
作者: Steven P Dehmer.;Michael V Maciosek.;Thomas J Flottemesch.;Amy B LaFrance.;Evelyn P Whitlock.
来源: Ann Intern Med. 2016年164卷12期777-86页
Evidence indicates that aspirin is effective for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) but also increases the risk for gastrointestinal (GI) and cerebral hemorrhages.
512. Aspirin for the Prevention of Cancer Incidence and Mortality: Systematic Evidence Reviews for the U.S. Preventive Services Task Force.
作者: Jessica Chubak.;Evelyn P Whitlock.;Selvi B Williams.;Aruna Kamineni.;Brittany U Burda.;Diana S M Buist.;Melissa L Anderson.
来源: Ann Intern Med. 2016年164卷12期814-25页
Cancer is the second leading cause of death in the United States.
513. Aspirin for the Primary Prevention of Cardiovascular Events: A Systematic Evidence Review for the U.S. Preventive Services Task Force.
作者: Janelle M Guirguis-Blake.;Corinne V Evans.;Caitlyn A Senger.;Elizabeth A O'Connor.;Evelyn P Whitlock.
来源: Ann Intern Med. 2016年164卷12期804-13页
Cardiovascular disease (CVD) is the leading cause of death in the United States.
514. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force.
作者: Evelyn P Whitlock.;Brittany U Burda.;Selvi B Williams.;Janelle M Guirguis-Blake.;Corinne V Evans.
来源: Ann Intern Med. 2016年164卷12期826-35页
The balance between potential aspirin-related risks and benefits is critical in primary prevention.
516. In the Clinic. Substance Use Disorders.
This issue provides a clinical overview of substance use disorders, focusing on epidemiology, prevention, diagnosis, complications, and management. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.
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