406. Blood Measurement of Carcinoembryonic Antigen Level for Detecting Recurrence of Colorectal Cancer.
What is the trade-off between sensitivity and specificity at specific carcinoembryonic antigen (CEA) thresholds for detecting recurrent colorectal cancer?
407. Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?
作者: Peter Bentzer.;Donald E Griesdale.;John Boyd.;Kelly MacLean.;Demetrios Sirounis.;Najib T Ayas.
来源: JAMA. 2016年316卷12期1298-309页
Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration.
408. Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.
作者: Michael G Silverman.;Brian A Ference.;Kyungah Im.;Stephen D Wiviott.;Robert P Giugliano.;Scott M Grundy.;Eugene Braunwald.;Marc S Sabatine.
来源: JAMA. 2016年316卷12期1289-97页
The comparative clinical benefit of nonstatin therapies that reduce low-density lipoprotein cholesterol (LDL-C) remains uncertain.
409. Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis.
作者: Jeffrey L Saver.;Mayank Goyal.;Aad van der Lugt.;Bijoy K Menon.;Charles B L M Majoie.;Diederik W Dippel.;Bruce C Campbell.;Raul G Nogueira.;Andrew M Demchuk.;Alejandro Tomasello.;Pere Cardona.;Thomas G Devlin.;Donald F Frei.;Richard du Mesnil de Rochemont.;Olvert A Berkhemer.;Tudor G Jovin.;Adnan H Siddiqui.;Wim H van Zwam.;Stephen M Davis.;Carlos Castaño.;Biggya L Sapkota.;Puck S Fransen.;Carlos Molina.;Robert J van Oostenbrugge.;Ángel Chamorro.;Hester Lingsma.;Frank L Silver.;Geoffrey A Donnan.;Ashfaq Shuaib.;Scott Brown.;Bruce Stouch.;Peter J Mitchell.;Antoni Davalos.;Yvo B W E M Roos.;Michael D Hill.; .
来源: JAMA. 2016年316卷12期1279-88页
Endovascular thrombectomy with second-generation devices is beneficial for patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the association of treatment time with outcomes would help to guide implementation.
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