265. Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans.
作者: Lisa M Abegglen.;Aleah F Caulin.;Ashley Chan.;Kristy Lee.;Rosann Robinson.;Michael S Campbell.;Wendy K Kiso.;Dennis L Schmitt.;Peter J Waddell.;Srividya Bhaskara.;Shane T Jensen.;Carlo C Maley.;Joshua D Schiffman.
来源: JAMA. 2015年314卷17期1850-60页
Evolutionary medicine may provide insights into human physiology and pathophysiology, including tumor biology.
267. Effect of Noninvasive Ventilation vs Oxygen Therapy on Mortality Among Immunocompromised Patients With Acute Respiratory Failure: A Randomized Clinical Trial.
作者: Virginie Lemiale.;Djamel Mokart.;Matthieu Resche-Rigon.;Frédéric Pène.;Julien Mayaux.;Etienne Faucher.;Martine Nyunga.;Christophe Girault.;Pierre Perez.;Christophe Guitton.;Kenneth Ekpe.;Achille Kouatchet.;Igor Théodose.;Dominique Benoit.;Emmanuel Canet.;François Barbier.;Antoine Rabbat.;Fabrice Bruneel.;Francois Vincent.;Kada Klouche.;Kontar Loay.;Eric Mariotte.;Lila Bouadma.;Anne-Sophie Moreau.;Amélie Seguin.;Anne-Pascale Meert.;Jean Reignier.;Laurent Papazian.;Ilham Mehzari.;Yves Cohen.;Maleka Schenck.;Rebecca Hamidfar.;Michael Darmon.;Alexandre Demoule.;Sylvie Chevret.;Elie Azoulay.; .
来源: JAMA. 2015年314卷16期1711-9页
Noninvasive ventilation has been recommended to decrease mortality among immunocompromised patients with hypoxemic acute respiratory failure. However, its effectiveness for this indication remains unclear.
268. Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial.
作者: Paul Young.;Michael Bailey.;Richard Beasley.;Seton Henderson.;Diane Mackle.;Colin McArthur.;Shay McGuinness.;Jan Mehrtens.;John Myburgh.;Alex Psirides.;Sumeet Reddy.;Rinaldo Bellomo.; .; .
来源: JAMA. 2015年314卷16期1701-10页
Saline (0.9% sodium chloride) is the most commonly administered intravenous fluid; however, its use may be associated with acute kidney injury (AKI) and increased mortality.
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