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2646. The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a narrative review.
作者: M Refik Gökmen.;Jean-Pierre Cosyns.;Volker M Arlt.;Marie Stiborová.;David H Phillips.;Heinz H Schmeiser.;Monique S J Simmonds.;H Terence Cook.;Jean-Louis Vanherweghem.;Joëlle L Nortier.;Graham M Lord.
来源: Ann Intern Med. 2013年158卷6期469-77页
It has been 20 years since the first description of a rapidly progressive renal disease that is associated with the consumption of Chinese herbs containing aristolochic acid (AA) and is now termed aristolochic acid nephropathy (AAN). Recent data have shown that AA is also the primary causative agent in Balkan endemic nephropathy and associated urothelial cancer. Aristolochic acid nephropathy is associated with a high long-term risk for renal failure and urothelial cancer, and the potential worldwide population exposure is enormous. This evidence-based review of the diagnostic approach to and management of AAN draws on the authors' experience with the largest and longest-studied combined cohort of patients with this condition. It is hoped that a better understanding of the importance of this underrecognized and severe condition will improve epidemiologic, preventive, and therapeutic strategies to reduce the global burden of this disease.
2648. GeoSentinel surveillance of illness in returned travelers, 2007-2011.
作者: Karin Leder.;Joseph Torresi.;Michael D Libman.;Jakob P Cramer.;Francesco Castelli.;Patricia Schlagenhauf.;Annelies Wilder-Smith.;Mary E Wilson.;Jay S Keystone.;Eli Schwartz.;Elizabeth D Barnett.;Frank von Sonnenburg.;John S Brownstein.;Allen C Cheng.;Mark J Sotir.;Douglas H Esposito.;David O Freedman.; .
来源: Ann Intern Med. 2013年158卷6期456-68页
International travel continues to increase, particularly to Asia and Africa. Clinicians are increasingly likely to be consulted for advice before travel or by ill returned travelers.
2649. Diagnostic accuracy of an "amended" insulin-glucose ratio for the biochemical diagnosis of insulinomas.
作者: Philip E Cryer.;Lloyd Axelrod.;Ashley B Grossman.;Simon R Heller.;Elizabeth R Seaquist.;F John Service.; .
来源: Ann Intern Med. 2013年158卷6期500-1页 2650. Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study.
作者: Irfan A Dhalla.;Tara Gomes.;Zhan Yao.;Jeff Nagge.;Navindra Persaud.;Chelsea Hellings.;Muhammad M Mamdani.;David N Juurlink.
来源: Ann Intern Med. 2013年158卷6期447-55页
Some evidence suggests that chlorthalidone may be superior to hydrochlorothiazide for the treatment of hypertension.
2652. Access to subspecialty care for patients with mobility impairment: a survey.
作者: Tara Lagu.;Nicholas S Hannon.;Michael B Rothberg.;Annalee S Wells.;K Laurie Green.;McAllister O Windom.;Katherine R Dempsey.;Penelope S Pekow.;Jill S Avrunin.;Aaron Chen.;Peter K Lindenauer.
来源: Ann Intern Med. 2013年158卷6期441-6页
Adults who use wheelchairs have difficulty accessing physicians and receive less preventive care than their able-bodied counterparts.
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