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2. Cost-Effectiveness of ApoB, Non-HDL-C, and LDL-C Goals for Primary Prevention Lipid-Lowering Therapy.
作者: Samuel Luebbe.;Allan D Sniderman.;Andrew E Moran.;John T Wilkins.;Ciaran N Kohli-Lynch.
来源: JAMA. 2026年
Apolipoprotein B (apoB) is a superior marker of residual atherosclerotic cardiovascular disease risk in patients treated with lipid-lowering therapy (LLT) compared with low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C). The cost-effectiveness of LDL-C, non-HDL-C, and apoB goals has not been established.
12. Discontinuation of Levothyroxine in Adults Aged 60 Years or Older.
作者: Janneke Ravensberg.;Jacobijn Gussekloo.;Saskia Le Cessie.;Olaf M Dekkers.;Simon P Mooijaart.;Rosalinde K E Poortvliet.
来源: JAMA. 2026年
Many adults aged 60 years or older take the thyroid hormone levothyroxine, which is generally continued for life. However, it is uncertain whether long-term continuation is always necessary.
18. Does This Child Have a Concussion?: The Rational Clinical Examination Systematic Review.
Concussion is a mild traumatic brain injury with associated abnormalities in brain function, rather than structural injury. An estimated 1.1 million to 1.9 million pediatric concussions occur annually in the US.
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