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1181. In NASH with liver fibrosis, resmetirom improved NASH resolution and reduced fibrosis at 1 y.
Harrison SA, Bedossa P, Guy CD, et al. MAESTRO-NASH Investigators. A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis. N Engl J Med. 2024;390:497-509. 38324483.
1183. Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men : A Randomized Controlled Trial.
作者: Yanxiao Gao.;Yuewei Zhan.;Yinghui Sun.;Weiran Zheng.;Weijie Zhang.;Leiwen Fu.;Zhihui Guo.;Yi-Fan Lin.;Yuwei Li.;Lingling Zheng.;Yiqiang Zhan.;Zhiqiang Zhu.;Junyi Duan.;Guanghui Zhang.;Tao Huang.;Bin Su.;Maohe Yu.;Guohui Wu.;Lin Ouyang.;Jin Zhao.;Guanghui Wang.;Yepeng Zhou.;Han-Zhu Qian.;Thomas Fitzpatrick.;Sten H Vermund.;Huachun Zou.
来源: Ann Intern Med. 2024年177卷6期719-728页
Observational studies suggest that voluntary medical male circumcision (VMMC) may lower HIV risk among men who have sex with men (MSM). A randomized controlled trial (RCT) is needed to confirm this.
1184. Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults : Real-World Evidence From a Target Trial Emulation Study.
作者: Wanchun Xu.;Amanda Lauren Lee.;Cindy Lo Kuen Lam.;Goodarz Danaei.;Eric Yuk Fai Wan.
来源: Ann Intern Med. 2024年177卷6期701-710页
There is little consensus on using statins for primary prevention of cardiovascular diseases (CVDs) and all-cause mortality in adults aged 75 years or older due to the underrepresentation of this population in randomized controlled trials.
1186. Extracorporeal Shock-Wave Lithotripsy and Endoscopy for the Treatment of Pain in Chronic Pancreatitis : A Sham-Controlled, Randomized Trial.
作者: Rupjyoti Talukdar.;Søren S Olesen.;Misbah Unnisa.;Akshay Bedarkar.;Subhaleena Sarkar.;Manu Tandan.;Nitin Jagtap.;Santosh Darisetty.;Sekhramantri Kiran.;Vinod Koppoju.;Sundeep Lakhtakia.;Mohan Ramchandani.;Rakesh Kalapala.;Rajesh Gupta.;Vikesh K Singh.;Guduru Venkat Rao.;Duvvur Nageshwar Reddy.;Asbjørn M Drewes.
来源: Ann Intern Med. 2024年177卷6期749-758页
No randomized controlled trials have substantiated endoscopic decompression of the pancreatic duct in patients with painful chronic pancreatitis.
1190. Lessons From the COVID-19 Pandemic: Updating Our Approach to Masking in Health Care Facilities.
作者: Eric J Chow.;John B Lynch.;Danielle M Zerr.;Francis X Riedo.;Mary Fairchok.;Steven A Pergam.;Christopher S Baliga.;John Pauk.;James Lewis.;Jeffrey S Duchin.
来源: Ann Intern Med. 2024年177卷5期689页 1199. Long COVID Definitions and Models of Care : A Scoping Review.
作者: Roger Chou.;Eric Herman.;Azrah Ahmed.;Jordan Anderson.;Shelley Selph.;Tracy Dana.;Leah Williams.;Ilya Ivlev.
来源: Ann Intern Med. 2024年177卷7期929-940页
Definitions of long COVID are evolving, and optimal models of care are uncertain.
1200. Association Between Autoimmune Diseases and Monoclonal Gammopathy of Undetermined Significance : An Analysis From a Population-Based Screening Study.
作者: Ingigerdur Sverrisdottir.;Sigrun Thorsteinsdottir.;Sæmundur Rognvaldsson.;Thor Aspelund.;Brynjar Vidarsson.;Pall Torfi Onundarson.;Bjarni A Agnarsson.;Margret Sigurdardottir.;Ingunn Thorsteinsdóttir.;Signy Vala Sveinsdottir.;Robert Palmason.;Isleifur Olafsson.;Fridbjorn Sigurdsson.;Asdis Rosa Thordardóttir.;Elias Eythorsson.;Asbjorn Jonsson.;Runolfur Palsson.;Olafur Skuli Indridason.;Gauti Kjartan Gislason.;Andri Olafsson.;Jon Sigurdsson.;Hlif Steingrímsdóttir.;Thorir Einarsson Long.;Malin Hultcrantz.;Brian G M Durie.;Stephen Harding.;Ola Landgren.;Sigurdur Yngvi Kristinsson.;Thorvardur Jon Love.
来源: Ann Intern Med. 2024年177卷6期711-718页
Monoclonal gammopathy of undetermined significance (MGUS) is a precursor of multiple myeloma (MM) and related conditions. In previous registry-based, retrospective studies, autoimmune diseases have been associated with MGUS. However, these studies were not based on a screened population and are therefore prone to ascertainment bias.
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