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8321. Emergence of a Novel SARS-CoV-2 Variant in Southern California.
作者: Wenjuan Zhang.;Brian D Davis.;Stephanie S Chen.;Jorge M Sincuir Martinez.;Jasmine T Plummer.;Eric Vail.
来源: JAMA. 2021年325卷13期1324-1326页
This research describes findings of sequencing and phylogenetic analyses of SARS-CoV-2 isolates from symptomatic patients cared for at Cedar-Sinai Medical Center in November-December 2020 during a regional surge in cases and hospitalizations.
8325. Changes in Shooting Incidence in Philadelphia, Pennsylvania, Between March and November 2020.
作者: Jessica H Beard.;Sara F Jacoby.;Zoë Maher.;Beidi Dong.;Elinore J Kaufman.;Amy J Goldberg.;Christopher N Morrison.
来源: JAMA. 2021年325卷13期1327-1328页
This study uses police department registry data to describe trends in incidence of firearm shootings and deaths in January-November 2020, before and after the closure of nonessential businesses in March, the killing of George Floyd in May, and the partial lifting of containment policies in June.
8331. Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.
Osteoarthritis (OA) is the most common joint disease, affecting an estimated more than 240 million people worldwide, including an estimated more than 32 million in the US. Osteoarthritis is the most frequent reason for activity limitation in adults. This Review focuses on hip and knee OA.
8334. Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial.
作者: Gregory Ducrocq.;Jose R Gonzalez-Juanatey.;Etienne Puymirat.;Gilles Lemesle.;Marine Cachanado.;Isabelle Durand-Zaleski.;Joan Albert Arnaiz.;Manuel Martínez-Sellés.;Johanne Silvain.;Albert Ariza-Solé.;Emile Ferrari.;Gonzalo Calvo.;Nicolas Danchin.;Cristina Avendaño-Solá.;Jerome Frenkiel.;Alexandra Rousseau.;Eric Vicaut.;Tabassome Simon.;Philippe Gabriel Steg.; .
来源: JAMA. 2021年325卷6期552-560页
The optimal transfusion strategy in patients with acute myocardial infarction and anemia is unclear.
8335. Prevalence of Bicuspid Aortic Valve and Associated Aortopathy in Newborns in Copenhagen, Denmark.
作者: Anne-Sophie Sillesen.;Ottilia Vøgg.;Christian Pihl.;Anna Axelsson Raja.;Karin Sundberg.;Cathrine Vedel.;Helle Zingenberg.;Finn Stener Jørgensen.;Niels Vejlstrup.;Kasper Iversen.;Henning Bundgaard.
来源: JAMA. 2021年325卷6期561-567页
The prevalence and characteristics of bicuspid aortic valve (BAV) are mainly reported from selected cohorts. BAV is associated with aortopathy, but it is unclear if it represents a fetal developmental defect or is secondary to abnormal valve dynamics.
8336. Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity Advice on Peak Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.
作者: Stephan Mueller.;Ephraim B Winzer.;André Duvinage.;Andreas B Gevaert.;Frank Edelmann.;Bernhard Haller.;Elisabeth Pieske-Kraigher.;Paul Beckers.;Anna Bobenko.;Jennifer Hommel.;Caroline M Van de Heyning.;Katrin Esefeld.;Pia von Korn.;Jeffrey W Christle.;Mark J Haykowsky.;Axel Linke.;Ulrik Wisløff.;Volker Adams.;Burkert Pieske.;Emeline M van Craenenbroeck.;Martin Halle.; .
来源: JAMA. 2021年325卷6期542-551页
Endurance exercise is effective in improving peak oxygen consumption (peak V̇o2) in patients with heart failure with preserved ejection fraction (HFpEF). However, it remains unknown whether differing modes of exercise have different effects.
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