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8285. SARS-CoV-2 Positivity on or After 9 Days Among Quarantined Student Contacts of Confirmed Cases.
作者: Eric J Nelson.;Sarah L McKune.;Kathleen A Ryan.;John A Lednicky.;Susanne R Crowe.;Paul D Myers.;J Glenn Morris.
来源: JAMA. 2021年325卷15期1561-1562页
This study describes coronavirus test positivity rates among elementary, middle, and high school student contacts of confirmed COVID-19 cases in a Florida county where schools required a negative test on day 9 before return to school on day 10.
8290. Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.
作者: Igor H Murai.;Alan L Fernandes.;Lucas P Sales.;Ana J Pinto.;Karla F Goessler.;Camila S C Duran.;Carla B R Silva.;André S Franco.;Marina B Macedo.;Henrique H H Dalmolin.;Janaina Baggio.;Guilherme G M Balbi.;Bruna Z Reis.;Leila Antonangelo.;Valeria F Caparbo.;Bruno Gualano.;Rosa M R Pereira.
来源: JAMA. 2021年325卷11期1053-1060页
The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear.
8291. Discriminant Accuracy of the SOFA Score for Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation.
作者: Robert A Raschke.;Sumit Agarwal.;Pooja Rangan.;C William Heise.;Steven C Curry.
来源: JAMA. 2021年325卷14期1469-1470页
This cohort study characterizes the accuracy of the Sequential Organ Failure Assessment (SOFA) score to discriminate death from survival in patients with COVID-19 pneumonia receiving oxygen therapy for 4 hours or longer before undergoing endotracheal intubation.
8297. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review.
Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new colorectal cancer diagnoses, 20% of patients have metastatic disease at presentation and another 25% who present with localized disease will later develop metastases.
8300. Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis: The START Randomized Clinical Trial.
作者: Stephen P Messier.;Shannon L Mihalko.;Daniel P Beavers.;Barbara J Nicklas.;Paul DeVita.;J Jeffery Carr.;David J Hunter.;Mary Lyles.;Ali Guermazi.;Kim L Bennell.;Richard F Loeser.
来源: JAMA. 2021年325卷7期646-657页
Thigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it may worsen knee symptoms.
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