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8141. Sudden Cardiac Death as First Manifestation of Heart Disease in Women: The Oregon Sudden Unexpected Death Study, 2004-2016.
作者: Kyndaron Reinier.;Eric C Stecker.;Audrey Uy-Evanado.;Harpriya S Chugh.;Andrea Binz.;Kotoka Nakamura.;Arayik Sargsyan.;Jonathan Jui.;Sumeet S Chugh.
来源: Circulation. 2020年141卷7期606-608页 8142. Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017.
作者: Xurui Jin.;Chanchal Chandramouli.;Brooke Allocco.;Enying Gong.;Carolyn S P Lam.;Lijing L Yan.
来源: Circulation. 2020年141卷7期540-548页
Cardiovascular disease is the leading cause of death among women worldwide, yet, women have historically been underrepresented in cardiovascular trials.
8143. Comparison of BNP and NT-proBNP in Patients With Heart Failure and Reduced Ejection Fraction.
作者: Rasmus Rørth.;Pardeep S Jhund.;Mehmet B Yilmaz.;Søren Lund Kristensen.;Paul Welsh.;Akshay S Desai.;Lars Køber.;Margaret F Prescott.;Jean L Rouleau.;Scott D Solomon.;Karl Swedberg.;Michael R Zile.;Milton Packer.;John J V McMurray.
来源: Circ Heart Fail. 2020年13卷2期e006541页
Both BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro B-type natriuretic peptide) are widely used to aid diagnosis, assess the effect of therapy, and predict outcomes in heart failure and reduced ejection fraction. However, little is known about how these 2 peptides compare in heart failure and reduced ejection fraction, especially with contemporary assays. Both peptides were measured at screening in the PARADIGM-HF trial (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure).
8144. Assessing and Mitigating Bias in Medical Artificial Intelligence: The Effects of Race and Ethnicity on a Deep Learning Model for ECG Analysis.
作者: Peter A Noseworthy.;Zachi I Attia.;LaPrincess C Brewer.;Sharonne N Hayes.;Xiaoxi Yao.;Suraj Kapa.;Paul A Friedman.;Francisco Lopez-Jimenez.
来源: Circ Arrhythm Electrophysiol. 2020年13卷3期e007988页
Deep learning algorithms derived in homogeneous populations may be poorly generalizable and have the potential to reflect, perpetuate, and even exacerbate racial/ethnic disparities in health and health care. In this study, we aimed to (1) assess whether the performance of a deep learning algorithm designed to detect low left ventricular ejection fraction using the 12-lead ECG varies by race/ethnicity and to (2) determine whether its performance is determined by the derivation population or by racial variation in the ECG.
8145. Granger Causality-Based Analysis for Classification of Fibrillation Mechanisms and Localization of Rotational Drivers.
作者: Balvinder S Handa.;Xinyang Li.;Kedar K Aras.;Norman A Qureshi.;Ian Mann.;Rasheda A Chowdhury.;Zachary I Whinnett.;Nick W F Linton.;Phang Boon Lim.;Prapa Kanagaratnam.;Igor R Efimov.;Nicholas S Peters.;Fu Siong Ng.
来源: Circ Arrhythm Electrophysiol. 2020年13卷3期e008237页
The mechanisms sustaining myocardial fibrillation remain disputed, partly due to a lack of mapping tools that can accurately identify the mechanism with low spatial resolution clinical recordings. Granger causality (GC) analysis, an econometric tool for quantifying causal relationships between complex time-series, was developed as a novel fibrillation mapping tool and adapted to low spatial resolution sequentially acquired data.
8146. Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia.
作者: Krystien V V Lieve.;Veronica Dusi.;Christian van der Werf.;J Martijn Bos.;Conor M Lane.;Mathis Korseberg Stokke.;Thomas M Roston.;Aurora Djupsjöbacka.;Yuko Wada.;Isabelle Denjoy.;Henning Bundgaard.;Ferran Roses I Noguer.;Christopher Semsarian.;Tomas Robyns.;Nynke Hofman.;Michael W Tanck.;Maarten P van den Berg.;Janneke A E Kammeraad.;Andrew D Krahn.;Sally-Ann B Clur.;Frederic Sacher.;Jan Till.;Jonathan R Skinner.;Jacob Tfelt-Hansen.;Vincent Probst.;Antoine Leenhardt.;Minoru Horie.;Heikki Swan.;Jason D Roberts.;Shubhayan Sanatani.;Kristina H Haugaa.;Peter J Schwartz.;Michael J Ackerman.;Arthur A M Wilde.
来源: Circ Arrhythm Electrophysiol. 2020年13卷3期e007471页
Risk stratification in catecholaminergic polymorphic ventricular tachycardia remains ill defined. Heart rate recovery (HRR) immediately after exercise is regulated by autonomic reflexes, particularly vagal tone, and may be associated with symptoms and ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia. Our objective was to evaluate whether HRR after maximal exercise on the exercise stress test (EST) is associated with symptoms and ventricular arrhythmias.
8147. Deep Learning-Based Quantification of Epicardial Adipose Tissue Volume and Attenuation Predicts Major Adverse Cardiovascular Events in Asymptomatic Subjects.
作者: Evann Eisenberg.;Priscilla A McElhinney.;Frederic Commandeur.;Xi Chen.;Sebastien Cadet.;Markus Goeller.;Aryabod Razipour.;Heidi Gransar.;Stephanie Cantu.;Robert J H Miller.;Piotr J Slomka.;Nathan D Wong.;Alan Rozanski.;Stephan Achenbach.;Balaji K Tamarappoo.;Daniel S Berman.;Damini Dey.
来源: Circ Cardiovasc Imaging. 2020年13卷2期e009829页
Epicardial adipose tissue (EAT) volume (cm3) and attenuation (Hounsfield units) may predict major adverse cardiovascular events (MACE). We aimed to evaluate the prognostic value of fully automated deep learning-based EAT volume and attenuation measurements quantified from noncontrast cardiac computed tomography.
8148. Multimodality Imaging in Hypertrophic Cardiomyopathy for Risk Stratification.
作者: Albree Tower-Rader.;Christopher M Kramer.;Stefan Neubauer.;Sherif F Nagueh.;Milind Y Desai.
来源: Circ Cardiovasc Imaging. 2020年13卷2期e009026页
In hypertrophic cardiomyopathy, multimodality imaging is crucial to confirm diagnosis, assess for presence and mechanism of left ventricular outflow tract obstruction, and risk stratification for sudden cardiac death. This review will focus on the application of imaging to assess established and emerging factors to be considered in sudden cardiac death risk stratification.
8150. Efficient 1-Hour Technetium-99 m Pyrophosphate Imaging Protocol for the Diagnosis of Transthyretin Cardiac Amyloidosis.
作者: Ahmad Masri.;Syed Bukhari.;Shahzad Ahmad.;Ricardo Nieves.;Yvonne S Eisele.;William Follansbee.;Amy Brownell.;Timothy C Wong.;Erik Schelbert.;Prem Soman.
来源: Circ Cardiovasc Imaging. 2020年13卷2期e010249页
Technetium-99 m pyrophosphate protocols for transthyretin cardiac amyloidosis diagnosis have variably used 1- and 3-hour imaging time points. We investigated whether imaging at 1 hour with superior efficiency had comparable diagnostic accuracy as 3-hour imaging.
8152. Sex Differences in Symptom Phenotypes Among Patients With Acute Myocardial Infarction.
作者: John E Brush.;Harlan M Krumholz.;Erich J Greene.;Rachel P Dreyer.
来源: Circ Cardiovasc Qual Outcomes. 2020年13卷2期e005948页
The diagnosis of acute myocardial infarction (AMI) is missed more frequently in young women than men, which may be related to the cognitive psychology of the diagnostic process. Physicians start the diagnostic process by intuitively recognizing familiar symptom phenotypes, but little is known about how symptoms combine in individuals as unique symptom phenotypes. We examined how symptoms of AMI combine as unique symptom phenotypes in individual patients to compare the distribution of symptom phenotypes in women versus men.
8160. SUPPORT-AF II: Supporting Use of Anticoagulants Through Provider Profiling of Oral Anticoagulant Therapy for Atrial Fibrillation: A Cluster-Randomized Study of Electronic Profiling and Messaging Combined With Academic Detailing for Providers Making Decisions About Anticoagulation in Patients With Atrial Fibrillation.
作者: Alok Kapoor.;Azraa Amroze.;Fatima Vakil.;Sybil Crawford.;Jacqueline Der.;Jomol Mathew.;Eric Alper.;Dinesh Yogaratnam.;Saud Javed.;Rasha Elhag.;Abraham Lin.;Siddhartha Narayanan.;Donna Bartlett.;Ahmed Nagy.;Bevin Kathleen Shagoury.;Michael A Fischer.;Kathleen M Mazor.;Jane S Saczynski.;Jeffrey M Ashburner.;Renato Lopes.;David D McManus.
来源: Circ Cardiovasc Qual Outcomes. 2020年13卷2期e005871页
Previous provider-directed electronic messaging interventions have not by themselves improved anticoagulation use in patients with atrial fibrillation. Direct engagement with providers using academic detailing coupled with electronic messaging may overcome the limitations of the prior interventions.
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