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7861. High rate of indeterminate results of the QuantiFERON-TB Gold in-tube test, third generation, in patients with systemic vasculitis.
作者: Stella Rousset.;Emmanuel Treiner.;Guillaume Moulis.;Grégory Pugnet.;Léonardo Astudillo.;Kim Paricaud.;Bénédicte Puissant-Lubrano.;Philippe Arlet.;Antoine Blancher.;Laurent Sailler.
来源: Rheumatology (Oxford). 2020年59卷5期1006-1010页
To describe the frequency of QuantiFERON-TB Gold in-tube test® (QFT-GIT) indeterminate results due to no response to phytohaemagglutinin A stimulation in the control tube in vasculitis patients prior to immunosuppressant therapy; and to compare it with other groups of patients.
7862. Glucocorticoids and steroid sparing medications monotherapies or in combination for IgG4-RD: a systematic review and network meta-analysis.
To assess the safety and efficacy of glucocorticoids (GCs), immunosuppressive agents (IM) and rituximab (RTX), alone or in combination, for the treatment of IgG4-RD.
7864. Long-term follow-up of patients in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial.
作者: Laura C Coates.;Farrouq Mahmood.;Jane Freeston.;Paul Emery.;Philip G Conaghan.;Philip S Helliwell.
来源: Rheumatology (Oxford). 2020年59卷4期807-810页
The TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) study was the first strategy trial in psoriatic arthritis using an early treat-to-target strategy to improve clinical outcomes. The current study aimed to review a cohort of patients who had completed TICOPA to judge if the clinical advantage gained by participants in the tight control (TC) arm was sustained, and to explore subsequent therapy.
7865. The performance of dual-energy CT in the classification criteria of gout: a prospective study in subjects with unclassified arthritis.
作者: Mihaela Gamala.;Johannes W G Jacobs.;Suzanne F Linn-Rasker.;Maarten Nix.;Ben G F Heggelman.;Pieternel C M Pasker-de Jong.;Jaap M van Laar.;Ruth Klaasen.
来源: Rheumatology (Oxford). 2020年59卷4期845-851页
To establish the performance of (subsets of) the 2015 ACR/EULAR gout classification criteria in patients with unclassified arthritis, and to determine the value of dual-energy CT (DECT) herein. Reference was the MSU crystal detection result in SF at polarization microscopy.
7867. Role of good oral hygiene on clinical evolution of rheumatoid arthritis: a randomized study nested in the ESPOIR cohort.
作者: Xavier Mariette.;Elodie Perrodeau.;Christian Verner.;Xavier Struillou.;Nicolas Picard.;Thierry Schaeverbeke.;Arnaud Constantin.;Philippe Ravaud.;Philippe Bouchard.
来源: Rheumatology (Oxford). 2020年59卷5期988-996页
There is a relationship between RA and periodontal disease. We aimed to investigate if a good oral hygiene could improve activity of RA.
7868. Elevated free secretory component in early rheumatoid arthritis and prior to arthritis development in patients at increased risk.
作者: Klara Martinsson.;Karin Roos Ljungberg.;Michael Ziegelasch.;Jan Cedergren.;Per Eriksson.;Vladimir Klimovich.;Åsa Reckner.;Irina Griazeva.;Christopher Sjöwall.;Marina Samoylovich.;Thomas Skogh.;Jonas Wetterö.;Alf Kastbom.
来源: Rheumatology (Oxford). 2020年59卷5期979-987页
Considering growing evidence of mucosal involvement in RA induction, this study investigated circulating free secretory component (SC) in patients with either recent-onset RA or with ACPA and musculoskeletal pain.
7869. Comparative safety of biologic versus conventional synthetic DMARDs in rheumatoid arthritis with COPD: a real-world population study.
作者: Marie Hudson.;Sophie Dell'Aniello.;Sophie Shen.;Teresa A Simon.;Pierre Ernst.;Samy Suissa.
来源: Rheumatology (Oxford). 2020年59卷4期820-827页
Abatacept, a biologic DMARD, was associated with respiratory adverse events in a small subgroup of RA patients with chronic obstructive pulmonary disease (COPD) in a trial. Whether this potential risk is specific to abatacept or extends to all biologics and targeted synthetic DMARDs (tsDMARDs) is unclear. We assessed the risk of adverse respiratory events associated with biologic and tsDMARDs compared with conventional synthetic DMARDs (csDMARDs) among RA patients with concomitant COPD in a large, real-world cohort.
7871. Joint microwave radiometry for inflammatory arthritis assessment.
作者: Katerina Laskari.;George Pentazos.;Despina Pitsilka.;John Raftakis.;George Konstantonis.;Konstantinos Toutouzas.;Elias Siores.;Maria Tektonidou.;Petros P Sfikakis.
来源: Rheumatology (Oxford). 2020年59卷4期839-844页
Increased in-depth joint temperature measured by the rapid, easy-to-perform microwave radiometry (MWR) method may reflect inflammation, even in the absence of clinical signs. We hypothesized that MWR is useful for RA and spondyloarthritis patients' assessment.
7872. Secretory anti-citrullinated protein antibodies in serum associate with lung involvement in early rheumatoid arthritis.
作者: Karin Roos Ljungberg.;Vijay Joshua.;Thomas Skogh.;Anders Eklund.;C Magnus Sköld.;Reza Karimi.;Sven Nyrén.;Anna Svärd.;Anca I Catrina.;Alf Kastbom.
来源: Rheumatology (Oxford). 2020年59卷4期852-859页
A 'mucosal connection' in RA presently attracts increasing attention. We recently described the occurrence of secretory antibodies to citrullinated protein (SC-ACPA) in sera from patients with recent-onset RA. The current study was performed to evaluate possible associations between serum levels of secretory ACPA and signs of lung involvement in patients with early, untreated RA.
7874. Clinical course of acute deep vein thrombosis of the legs in Behçet's syndrome.
作者: Yesim Ozguler.;Gulen Hatemi.;Firat Cetinkaya.;Koray Tascilar.;Vedat Hamuryudan.;Serdal Ugurlu.;Emire Seyahi.;Hasan Yazici.;Melike Melikoglu.
来源: Rheumatology (Oxford). 2020年59卷4期799-806页
Lower extremity deep vein thrombosis (LEDVT) is a serious complication of Behçet's syndrome. Management constitutes mainly of administration of immunosuppressives, but the predictors of relapse and the optimal choice of immunosuppressives remain unclear. In this prospective study, we aimed to detect the risk and predictors of relapse and treatment response to different modalities.
7875. Successful treatment of anti-MDA5 antibody-positive refractory interstitial lung disease with plasma exchange therapy.
作者: Yoshiyuki Abe.;Makio Kusaoi.;Kurisu Tada.;Ken Yamaji.;Naoto Tamura.
来源: Rheumatology (Oxford). 2020年59卷4期767-771页
We examined the effectiveness of plasma exchange (PE) therapy to reduce the mortality of rapidly progressive interstitial lung disease (RP-ILD) in patients positive for anti-melanoma differentiation-associated gene 5 (MDA5) antibodies.
7878. Health-related quality of life in systemic sclerosis before and after autologous haematopoietic stem cell transplant-a systematic review.
作者: Mathieu Puyade.;Nancy Maltez.;Pauline Lansiaux.;Grégory Pugnet.;Pascal Roblot.;Ines Colmegna.;Marie Hudson.;Dominique Farge.
来源: Rheumatology (Oxford). 2020年59卷4期779-789页
In severe rapidly progressive SSc, autologous haematopoietic stem cell transplantation (AHSCT) allows significant improvements in overall and event-free survival. We undertook this study to identify, appraise and synthesize the evidence on health-related quality of life (HRQoL) before and after AHSCT for SSc.
7879. Trends in all-cause and cardiovascular mortality in patients with incident rheumatoid arthritis: a 20-year follow-up matched case-cohort study.
作者: Sella A Provan.;Siri Lillegraven.;Joe Sexton.;Kristin Angel.;Cathrine Austad.;Espen A Haavardsholm.;Tore K Kvien.;Till Uhlig.
来源: Rheumatology (Oxford). 2020年59卷3期505-512页
To examine all-cause and cardiovascular disease (CVD) mortality in consecutive cohorts of patients with incident RA, compared with population comparators.
7880. STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE.
作者: Aurélie De Groof.;Julie Ducreux.;Floor Aleva.;Andrew J Long.;Alina Ferster.;Andre van der Ven.;Frank van de Veerdonk.;Frédéric A Houssiau.;Bernard R Lauwerys.
来源: Rheumatology (Oxford). 2020年59卷3期668-677页
Type I IFNs play a well-known role in the pathogenesis of SLE, through activation of CD4 T and antigen-presenting cells. Here, we investigated the effects of IFN alpha (IFNα) on SLE B cell activation and differentiation.
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