7285. Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial.
作者: Aitana Juan-Giner.;Derick Kimathi.;Kyra H Grantz.;Mainga Hamaluba.;Patrick Kazooba.;Patricia Njuguna.;Gamou Fall.;Moussa Dia.;Ndeye S Bob.;Thomas P Monath.;Alan D Barrett.;Joachim Hombach.;Edgar M Mulogo.;Immaculate Ampeire.;Henry K Karanja.;Dan Nyehangane.;Juliet Mwanga-Amumpaire.;Derek A T Cummings.;Philip Bejon.;George M Warimwe.;Rebecca F Grais.
来源: Lancet. 2021年397卷10269期119-127页
Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We assessed the immunogenicity and safety of one-fifth fractional dose compared with standard dose of four WHO-prequalified yellow fever vaccines produced from three substrains.
7297. Novichok nerve agent poisoning.
作者: David Steindl.;Wolfgang Boehmerle.;Roland Körner.;Damaris Praeger.;Marcel Haug.;Jens Nee.;Adrian Schreiber.;Franziska Scheibe.;Katharina Demin.;Philipp Jacoby.;Rudolf Tauber.;Sven Hartwig.;Matthias Endres.;Kai-Uwe Eckardt.
来源: Lancet. 2021年397卷10270期249-252页 |