7208. Effect of Sacubitril/Valsartan vs Standard Medical Therapies on Plasma NT-proBNP Concentration and Submaximal Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction: The PARALLAX Randomized Clinical Trial.
作者: Burkert Pieske.;Rolf Wachter.;Sanjiv J Shah.;Abigail Baldridge.;Peter Szeczoedy.;Ghionul Ibram.;Victor Shi.;Ziqiang Zhao.;Martin R Cowie.; .
来源: JAMA. 2021年326卷19期1919-1929页
There is limited evidence on the benefits of sacubitril/valsartan vs broader renin angiotensin system inhibitor background therapy on surrogate outcome markers, 6-minute walk distance, and quality of life in patients with heart failure and mildly reduced or preserved left ventricular ejection fraction (LVEF >40%).
7220. Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis.
作者: Ali Aminian.;Abbas Al-Kurd.;Rickesha Wilson.;James Bena.;Hana Fayazzadeh.;Tavankit Singh.;Vance L Albaugh.;Faiz U Shariff.;Noe A Rodriguez.;Jian Jin.;Stacy A Brethauer.;Srinivasan Dasarathy.;Naim Alkhouri.;Philip R Schauer.;Arthur J McCullough.;Steven E Nissen.
来源: JAMA. 2021年326卷20期2031-2042页
No therapy has been shown to reduce the risk of serious adverse outcomes in patients with nonalcoholic steatohepatitis (NASH).
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