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662. Discordance in Creatinine- and Cystatin C-Based eGFR and Clinical Outcomes: A Meta-Analysis.
作者: Michelle M Estrella.;Shoshana H Ballew.;Yingying Sang.;Morgan E Grams.;Josef Coresh.;Aditya Surapaneni.;Natalia Alencar de Pinho.;Johan Ärnlöv.;Hermann Brenner.;Juan-Jesus Carrero.;Teresa K Chen.;Debbie L Cohen.;Mary Cushman.;Ron T Gansevoort.;Shih-Jen Hwang.;Lesley A Inker.;Joachim H Ix.;Keiko Kabasawa.;Tsuneo Konta.;Jennifer S Lees.;Kevan R Polkinghorne.;Michael G Shlipak.;Robin W M Vernooij.;David C Wheeler.;Ashok Kumar Yadav.;Andrew S Levey.;Kai-Uwe Eckardt.; .
来源: JAMA. 2025年334卷21期1915-1926页
Estimated glomerular filtration rates (eGFRs) can differ according to whether creatinine or cystatin C is used for the eGFR calculation, but the prevalence and importance of these differences remain unclear.
664. Effects of Sodium Glucose Cotransporter 2 Inhibitors by Diabetes Status and Level of Albuminuria: A Meta-Analysis.
作者: Natalie Staplin.;Alistair J Roddick.;Brendon L Neuen.;Stefan D Anker.;Deepak L Bhatt.;Javed Butler.;David Z Cherney.;Kieran F Docherty.;Robert A Fletcher.;Silvio E Inzucchi.;Meg Jardine.;Kenneth W Mahaffey.;Darren K McGuire.;John J V McMurray.;Bruce Neal.;Milton Packer.;Siddharth M Patel.;Vlado Perkovic.;Marc S Sabatine.;Scott Solomon.;Muthiah Vaduganathan.;Christoph Wanner.;David C Wheeler.;Faiez Zannad.;Richard Haynes.;Hiddo J L Heerspink.;William G Herrington.; .
来源: JAMA. 2026年335卷3期220-232页
There is uncertainty about the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in participants with chronic kidney disease, with guidelines offering different strengths of recommendation based on diabetes status and urine albumin to creatinine ratio (UACR).
666. A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial.
作者: Kathleen D Liu.;Edward D Siew.;Delphine S Tuot.;Anitha Vijayan.;Gonzalo Matzumura Umemoto.;Bethany C Birkelo.;Benjamin J Lee.;Y Diana Kwong.;Ian E McCoy.;Kevin Delucchi.;Hanjing Zhuo.;Chi-Yuan Hsu.
来源: JAMA. 2026年335卷4期326-335页
For patients with dialysis-requiring acute kidney injury, persistent need for dialysis is associated with increased morbidity and mortality, high health care use, and poor quality of life.
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