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6221. AGA Technical Review on Intragastric Balloons in the Management of Obesity.
作者: Raj Shah.;Perica Davitkov.;Barham K Abu Dayyeh.;Monica Saumoy.;M Hassan Murad.
来源: Gastroenterology. 2021年160卷5期1811-1830页
Several strategies are available to address the obesity epidemic and range from noninvasive lifestyle interventions to medications and bariatric surgical procedures. Endoscopic bariatric techniques, such as intragastric balloons, have become an attractive alternative as a tool for weight loss that can augment the effect of lifestyle interventions. This technical review includes multiple systematic reviews performed to support a clinical practice guideline by the American Gastroenterological Association on the role of intragastric balloons as a tool for weight loss. The systematic reviews targeted a priori selected clinical questions about the effectiveness and periprocedural care of intragastric balloons and concomitant and subsequent weight-loss strategies.
6224. AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity.
作者: Thiruvengadam Muniraj.;Lukejohn W Day.;Levi M Teigen.;Edith Y Ho.;Shahnaz Sultan.;Perica Davitkov.;Raj Shah.;M Hassan Murad.
来源: Gastroenterology. 2021年160卷5期1799-1808页 6225. Gastrointestinal symptoms as first remarkable signs of ANCA-associated granulomatosis with polyangiitis: a case report and reviews.
Systemic vasculitis associated with antineutrophil cytoplasmic autoantibodies (ANCA) have an extremely wide variety of symptoms, therefore the fast and proper diagnosis is difficult to establish even for experienced physicians. Gastrointestinal manifestations in ANCA-associated granulomatosis with polyangiitis (GPA) may be present, however, severe, life-threatening complications (such as perforations) are rare.
6229. Triglycerides to high-density lipoprotein cholesterol ratio for diagnosing nonalcoholic fatty liver disease.
作者: Roberto Catanzaro.;Federica Selvaggio.;Morena Sciuto.;Luca Zanoli.;Azam Yazdani.;Fang He.;Francesco Marotta.
来源: Minerva Gastroenterol (Torino). 2022年68卷3期261-268页
Nonalcoholic Fatty Liver Disease (NAFLD) is a widespread disease in the western world. It can develop into more serious pathological conditions (i.e. liver cirrhosis). Therefore, it is important to diagnose it in order to prevent this evolution. For diagnosis it is possible to use both imaging methods and biomarkers, such as the Triglycerides To High-Density Lipoprotein Cholesterol Ratio (TG/HDL-C). Aim of our study is to determine whether TG/HDL-C ratio is significantly associated with NAFLD and Metabolic Syndrome (MetS).
6230. Renal dysfunctions and liver disease: a brief update on management with particular attention to hepatorenal syndrome.
作者: Monica Surace.;Immacolata Andria.;Giovanni Valentini.
来源: Minerva Gastroenterol (Torino). 2023年69卷3期412-422页
In 2015 the International Club of Ascites gave an accurate, exact and new definition of acute renal injury in cirrhotic patient, identifying objective criteria of severity and recoding hepatorenal syndrome as a particular form of renal dysfunction for which excessive renal vasoconstriction is one of the main, but not the only, pathophysiological mechanisms. In this review we tried to outline new pathophysiological and therapeutic insights, and to summarize the most recent recommendations. Vasopressor such as terlipressin and norepinephrine, in combination with albumin, still represent the first line therapy. However, the new discoveries in the pathophysiology of the disease have led the search for new pharmacological approaches, although, to date, the only definitive remedy is represented by liver (or simultaneous liver-kidney) transplantation.
6231. The effects of dietary intervention on fibrosis and biochemical parameters in metabolic-associated fatty liver disease.
Metabolic-associated fatty liver disease (MAFLD) affects nearly one quarter of the world's adult population creating large health loads and economic loads in society with no approved pharmacotherapy found yet. The number of studies showing the effect of nutrition on fibrosis accompanying MAFLD are insufficient. This study was planned with the aim of investigating the effect of nutritional treatment on liver injury.
6232. Does fecal calprotectin increase may be linked to lactose intolerance in patients with irritable bowel syndrome?
作者: Marine Guingand DE Rivery.;Hamidou Zeinab.;Valérie Cohen.;Karine Baumstarck.;Laure Luciano.;Véronique Vitton.
来源: Minerva Gastroenterol (Torino). 2023年69卷3期329-334页
Irritable bowel syndrome (IBS) is a multifactorial condition without any specific investigation. Fecal calprotectin (FC) may be elevated in IBS without any explanation. In addition, some patients with IBS have symptoms related to lactose intolerance. Our main aim was to investigate whether an increase in FC could be related to lactose intolerance in patients with IBS.
6233. A rapid preliminary prediction model for intestinal necrosis in acute mesenteric ischemia: a retrospective study.
作者: Xinsuo Zhuang.;Fumei Chen.;Qian Zhou.;Yuanrun Zhu.;Xiaofeng Yang.
来源: BMC Gastroenterol. 2021年21卷1期154页
Acute mesenteric ischemia (AMI) is a life-threatening condition. However, there is no accurate method to predict intestinal necrosis in AMI patients that may facilitate early surgical intervention. This study thus aimed to explore a simple and accurate model to predict intestinal necrosis in patients with AMI.
6234. Chemotherapy alone versus definitive concurrent chemoradiotherapy for cT4b esophageal squamous cell carcinoma: a population-based study.
作者: Chia-Chin Li.;Chih-Yi Chen.;Ying-Hsiang Chou.;Chih-Jen Huang.;Hsiu-Ying Ku.;Chun-Ru Chien.
来源: BMC Gastroenterol. 2021年21卷1期153页
The role of radiotherapy for cT4bNanyM0 esophageal squamous cell carcinoma (ESqCC) is relatively unclear, with both chemotherapy (C/T) alone and definitive concurrent chemoradiotherapy (dCCRT) being treatment options in the current guidelines. We aimed to compare the survival of dCCRT versus C/T for these patients via a population-based approach.
6235. Absent or impaired rectoanal inhibitory reflex as a diagnostic factor for high-grade (grade III-V) rectal prolapse: a retrospective study.
作者: Byung-Soo Park.;Sung Hwan Cho.;Gyung Mo Son.;Hyun Sung Kim.;Yong-Hoon Cho.;Dae Gon Ryu.;Su Jin Kim.;Su Bum Park.;Cheol Woong Choi.;Hyung Wook Kim.;Tae Un Kim.;Dong Soo Suh.;Myunghee Yoon.;Hong Jae Jo.
来源: BMC Gastroenterol. 2021年21卷1期157页
Clinically diagnosing high-grade (III-V) rectal prolapse might be difficult, and the prolapse can often be overlooked. Even though defecography is the significant diagnostic tool for rectal prolapse, it is noticed that rectoanal inhibitory reflex (RAIR) can be associated with rectal prolapse. This study investigated whether RAIR can be used as a diagnostic factor for rectal prolapse.
6236. Differentiation of small (≤ 3 cm) hepatocellular carcinomas from benign nodules in cirrhotic liver: the added additive value of MRI-based radiomics analysis to LI-RADS version 2018 algorithm.
作者: Xi Zhong.;Tianpei Guan.;Danrui Tang.;Jiansheng Li.;Bingui Lu.;Shuzhong Cui.;Hongsheng Tang.
来源: BMC Gastroenterol. 2021年21卷1期155页
Accurate characterization of small nodules in a cirrhotic liver is challenging. We aimed to determine the additive value of MRI-based radiomics analysis to Liver Imaging Reporting and Data System version 2018 (LI-RADS v 2018) algorithm in differentiating small (≤ 3 cm) hepatocellular carcinomas (HCCs) from benign nodules in cirrhotic liver.
6237. The inverse association between unhealthy eating habit and mucosal healing among patients with ulcerative colitis.
作者: Shinya Furukawa.;Sen Yagi.;Kana Shiraishi.;Yu Hashimoto.;Shogo Kitahata.;Masakazu Hanayama.;Kazuhiro Tange.;Kenichiro Mori.;Tomoyuki Ninomiya.;Seiyuu Suzuki.;Naozumi Shibata.;Hidehiro Murakami.;Katsuhisa Ohashi.;Aki Hasebe.;Hideomi Tomida.;Yasunori Yamamoto.;Eiji Takeshita.;Yoshio Ikeda.;Yoichi Hiasa.
来源: BMC Gastroenterol. 2021年21卷1期152页
Although the association between eating habits which can be modified and digestive diseases has been reported, to date, no research has evaluated the association between eating habits and ulcerative colitis (UC). Thus, we investigate the association between eating behavior and clinical outcome in Japanese patients with UC.
6238. Clinical characteristics and surgical treatments of primary hepatic angiosarcoma.
作者: Lei Jiang.;Lijun Xie.;Ge Li.;Hang Xie.;Zhao Fang.;Xinran Cai.;Yanling Chen.
来源: BMC Gastroenterol. 2021年21卷1期156页
Primary hepatic angiosarcoma is a very rare and highly malignant tumor with poor prognosis. It is difficult to diagnose because of the lack of typical clinical features, and the treatment protocols for PHA are also not clear. Therefore, this study wants to find out the clinical characteristics and surgical treatments of primary hepatic angiosarcoma.
6239. Ectopic pancreas appearing as a giant gastric cyst mimicking gastric lymphangioma: a case report and a brief review.
Ectopic pancreas (EP) is defined as pancreatic tissue that lacks anatomical or vascular communication with the normal body of the pancreas. Despite improvements in diagnostic endoscopy and imaging studies, differentiating ectopic pancreatic tissue from gastric submucosal diseases remains a challenge.
6240. Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.
作者: Martijn A J Koppens.;Hayley Davis.;Gabriel N Valbuena.;Eoghan J Mulholland.;Nadia Nasreddin.;Mathilde Colombe.;Agne Antanaviciute.;Sujata Biswas.;Matthias Friedrich.;Lennard Lee.; .;Lai Mun Wang.;Viktor H Koelzer.;James E East.;Alison Simmons.;Douglas J Winton.;Simon J Leedham.
来源: Gastroenterology. 2021年161卷1期239-254.e9页
In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signaling. The bone morphogenetic protein (BMP) pathway has a physiological, prodifferentiation role, predominantly inferred through previous experimental pathway inactivation. Intestinal regeneration is underpinned by dedifferentiation and cell plasticity, but the signaling pathways that regulate this adaptive reprogramming are not well understood. We assessed the BMP signaling landscape and investigated the impact and therapeutic potential of pathway manipulation in homeostasis and regeneration.
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