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5590. Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study.
作者: Cristina Menni.;Ana M Valdes.;Lorenzo Polidori.;Michela Antonelli.;Satya Penamakuri.;Ana Nogal.;Panayiotis Louca.;Anna May.;Jane C Figueiredo.;Christina Hu.;Erika Molteni.;Liane Canas.;Marc F Österdahl.;Marc Modat.;Carole H Sudre.;Ben Fox.;Alexander Hammers.;Jonathan Wolf.;Joan Capdevila.;Andrew T Chan.;Sean P David.;Claire J Steves.;Sebastien Ourselin.;Tim D Spector.
来源: Lancet. 2022年399卷10335期1618-1624页
The SARS-CoV-2 variant of concern, omicron, appears to be less severe than delta. We aim to quantify the differences in symptom prevalence, risk of hospital admission, and symptom duration among the vaccinated population.
5592. Health system performance in Iran: a systematic analysis for the Global Burden of Disease Study 2019.
Better evaluation of existing health programmes, appropriate policy making against emerging health threats, and reducing inequalities in Iran rely on a comprehensive national and subnational breakdown of the burden of diseases, injuries, and risk factors.
5597. Aggressive intraoperative warming versus routine thermal management during non-cardiac surgery (PROTECT): a multicentre, parallel group, superiority trial.
作者: Daniel I Sessler.;Lijian Pei.;Kai Li.;Shusen Cui.;Matthew T V Chan.;Yuguang Huang.;Jingxiang Wu.;Xuemei He.;Gausan R Bajracharya.;Eva Rivas.;Carmen K M Lam.; .
来源: Lancet. 2022年399卷10337期1799-1808页
Moderate intraoperative hypothermia promotes myocardial injury, surgical site infections, and blood loss. Whether aggressive warming to a truly normothermic temperature near 37°C improves outcomes remains unknown. We aimed to test the hypothesis that aggressive intraoperative warming reduces major perioperative complications.
5598. Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial.
作者: Felix Mahfoud.;David E Kandzari.;Kazuomi Kario.;Raymond R Townsend.;Michael A Weber.;Roland E Schmieder.;Konstantinos Tsioufis.;Stuart Pocock.;Kyriakos Dimitriadis.;James W Choi.;Cara East.;Richard D'Souza.;Andrew S P Sharp.;Sebastian Ewen.;Antony Walton.;Ingrid Hopper.;Sandeep Brar.;Pamela McKenna.;Martin Fahy.;Michael Böhm.
来源: Lancet. 2022年399卷10333期1401-1410页
Renal denervation has been shown to lower blood pressure in the presence of antihypertensive medications; however, long-term safety and efficacy data from randomised trials of renal denervation are lacking. In this pre-specified analysis of the SPYRAL HTN-ON MED study, we compared changes in blood pressure, antihypertensive drug use, and safety up to 36 months in renal denervation versus a sham control group.
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