525. Prediction of Bacteremia and Bacterial Meningitis Among Febrile Infants Aged 28 Days or Younger.
作者: Brett Burstein.;Thomas Waterfield.;Etimbuk Umana.;Jianling Xie.;Nathan Kuppermann.
来源: JAMA. 2026年335卷5期425-433页
Fever in the first month of life is often the only sign of life-threatening invasive bacterial infection, specifically bacteremia or bacterial meningitis. Most international guidelines recommend routine lumbar punctures for all febrile infants 28 days or younger to rule out bacterial meningitis. Clinical prediction rules may allow for select testing, but limited information exists on their performance to identify infants at low risk for invasive bacterial infections.
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