389. Acetaminophen (Paracetamol) or Opioid Analgesia Added to Ibuprofen for Children's Musculoskeletal Injury: Two Randomized Clinical Trials.
作者: Samina Ali.;Terry P Klassen.;Patricia Candelaria.;Maala Bhatt.;Scott Sawyer.;Antonia Stang.;Maryna Yaskina.;Anna Heath.;Petros Pechlivanoglou.;Martin Offringa.;Amy L Drendel.;Serena Hickes.;Naveen Poonai.; .
来源: JAMA. 2026年335卷10期863-873页
Ibuprofen is first-line therapy for musculoskeletal pain. However, two-thirds of children experience inadequate pain relief with ibuprofen monotherapy, and the efficacy of additive medications for moderate to severe musculoskeletal pain is unclear.
393. Interim Safety of RSVpreF Vaccination During Pregnancy.
作者: Ashley I Michnick.;Sarah C MacDonald.;Austin Cosgrove.;Sruthi Adimadhyam.;Fang Zhang.;Andrew B Petrone.;Katherine E Round.;Sampada Gandhi.;Nana Koram.;Olympia E Anastasiou.;Heather Rubino.;Maria Maddalena Lino.;Djeneba A Djibo.;Jennifer L Kuntz.;Shelly-Ann M Love.;Cheryl N McMahill-Walraven.;Kristin Palmsten.;Anna E Wentz.;Judith C Maro.;Richard Platt.;Susan E Andrade.
来源: JAMA. 2026年335卷5期456-459页 399. Prenatal Exposure to Acid-Suppressive Medications and Risk of Neuropsychiatric Disorders in Children.
作者: Seohyun Hong.;Sooji Lee.;Hyunjee Kim.;Hyesu Jo.;Kyeongmin Lee.;Yeona Jo.;Tae Hyeon Kim.;Jaeyu Park.;Jinseok Lee.;Ho Geol Woo.;Hayeon Lee.;Dong Keon Yon.
来源: JAMA. 2026年335卷7期609-618页
Although acid-suppressive medications are commonly prescribed during pregnancy, comprehensive studies on their association with neuropsychiatric disorders in children are limited.
400. Gastric Cancer: A Review.
Globally, 968 350 new cases and 659 853 deaths from gastric cancer were reported in 2022. In the US, 30 300 new cases and 10 780 deaths were estimated in 2025.
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