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391. An 85-Year-Old Man With Dyspnea and a History of Hormone Therapy for Prostate Adenocarcinoma.
作者: Koki Nakashima.;Chiaki Tomoi.;Toshiko Kakiuchi.;Shiori Saikawa.;Kazunari Igarashi.;Tamotsu Ishizuka.
来源: Chest. 2025年168卷3期e69-e74页
An 85-year-old man had undergone hormone therapy with bicalutamide (androgen receptor antagonist) and leuprorelin (gonadotropin-releasing hormone agonist) for prostate adenocarcinoma with a Gleason score of 4 + 5 for approximately 3 years. The patient presented to the emergency department with dyspnea, respiratory failure, and loss of appetite. He also had a history of COPD with a 20-pack-year smoking history. The patient worked as a cook and had no history of occupational exposure to asbestos. Chest radiography showed a left pleural effusion , and he was admitted to our hospital for further examination of the pleural effusion.
392. A 27-Year-Old Woman With Rapidly Progressive Shortness of Breath and Severe Alopecia.
A 27-year-old previously healthy woman with no known exposure history presented with a 20-day history of progressively worsening breathlessness. She progressed from being breathless while hurrying on level ground to becoming breathless at rest and unable to complete sentences within 2 days. She reported multiple episodes of hemoptysis (approximately 30 mL daily) over the past 6 to 7 days, along with generalized weakness and fatigue for the last 7 days, and sudden onset of hair loss for the past 2 days. She reported episodic bluish discoloration of fingers on exposure to cold for the last 3 years but denied history of joint pain or skin rash.
393. Management of Pulmonary Granulomatous Venulitis by Lung Transplantation.
作者: Ariel M McKenna.;Anupama Tiwari.;Amit Chopra.;Llewellyn Foulke.;Maria M Crespo.;Harrison W Farber.
来源: Chest. 2025年168卷3期e59-e63页
Granulomatous venulitis is an exceedingly rare condition characterized by granulomatous inflammation and obliteration of small pulmonary veins, leading to the development of pulmonary venoocclusive disease. The prognosis is poor, with most patients surviving less than 1 year after diagnosis. We present the first case, to our knowledge, of successful management of this disease by lung transplantation.
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