2881. In moderately severe CAP stable after 3 d of β-lactam, stopping therapy was noninferior to 5 additional d.
Dinh A, Ropers J, Duran C, et al. Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial. Lancet. 2021;397:1195-1203. 33773631.
2882. In decompensated cirrhosis, targeted albumin infusions did not improve an in-hospital composite outcome at 15 d.
China L, Freemantle N, Forrest E, et al. A randomized trial of albumin infusions in hospitalized patients with cirrhosis. N Engl J Med. 2021;384:808-17. 33657293.
2883. In hospitalized patients with substance use disorders, the NavSTAR service model reduced readmission at 1 y.
Gryczynski J, Nordeck CD, Welsh C, et al. Preventing hospital readmission for patients with comorbid substance use disorder: a randomized trial. Ann Intern Med. 2021;174:899-909. 33819055.
2885. 1-step screening approach detected more GDM than 2-step approach but did not improve clinical outcomes.
Hillier TA, Pedula KL, Ogasawara KK, et al. A pragmatic, randomized clinical trial of gestational diabetes screening. N Engl J Med. 2021;384:895-904. 33704936.
2886. In patients with COVID-19, viral shedding time is 17 d and varies in some subgroups.
Yan D, Zhang X, Chen C, et al. Characteristics of viral shedding time in SARS-CoV-2 infections: a systematic review and meta-analysis. Front Public Health. 2021;9:652842. 33816427.
2887. In premature ejaculation, SSRIs improve self-perceived symptoms and satisfaction vs. placebo.
Sathianathen NJ, Hwang EC, Mian R, et al. Selective serotonin re-uptake inhibitors for premature ejaculation in adult men. Cochrane Database Syst Rev. 2021;3:CD012799. 33745183.
2890. Mandating COVID-19 Vaccination for Health Care Workers.
It is imperative that all 17 million health care workers in the United States be vaccinated against COVID-19. The authors believe that the best way to achieve this is for the workers to choose vaccination, but given the current situation, the authors feel that health care employers should mandate vaccination. A joint statement signed by dozens of health care professional societies and organizations endorses this requirement.
2891. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality : A Prospective Cohort Study.
作者: Mahdi Sheikh.;Anush Mukeriya.;Oxana Shangina.;Paul Brennan.;David Zaridze.
来源: Ann Intern Med. 2021年174卷9期1232-1239页
Lung cancer is the leading cause of cancer death worldwide, and about one half of patients with lung cancer are active smokers at diagnosis.
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