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2261. Preventing Obesity in Midlife Women: A Recommendation From the Women's Preventive Services Initiative.
作者: David Chelmow.;Kimberly D Gregory.;Catherine Witkop.;Susan Hoffstetter.;Linda Humphrey.;Carla Picardo.;James J Stevermer.;Amy G Cantor.;Heidi D Nelson.;Sarah Son.;Jeanne A Conry.;Francisco Garcia.;Susan M Kendig.;Nancy O'Reilly.;Amir Qaseem.;Diana Ramos.;Alina Salganicoff.;Julie K Wood.;Christopher Zahn.; .
来源: Ann Intern Med. 2022年175卷9期1305-1309页
The Women's Preventive Services Initiative (WPSI), a national coalition of women's health professional organizations and patient advocacy representatives, developed a recommendation for counseling midlife women aged 40 to 60 years with normal or overweight body mass index (BMI; 18.5 to 29.9 kg/m2) to maintain weight or limit weight gain to prevent obesity with the long-term goals of optimizing health, function, and well-being. This recommendation is intended to guide clinical practice and coverage of clinical preventive health services for the Health Resources and Services Administration and other stakeholders. Clinicians providing preventive health care to women in primary care settings are the target audience for this recommendation.
2262. In HF, SGLT2 inhibitors reduce HF hospitalizations at up to 2 y.
Zou X, Shi Q, Vandvik PO, et al. Sodium-glucose cotransporter-2 inhibitors in patients with heart failure: a systematic review and meta-analysis. Ann Intern Med. 2022;175:851-61. 35404670.
2263. In drug-refractory IBS, group CBT with interoceptive exposure improved symptoms and QoL at 13 wk.
Kikuchi S, Oe Y, Ito Y, et al. Group cognitive-behavioral therapy with interoceptive exposure for drug-refractory irritable bowel syndrome: a randomized controlled trial. Am J Gastroenterol. 2022;117:668-77. 35103022.
2264. mRNA COVID-19 vaccines were linked to myocarditis at 28 d (0.15 to 10 excess events/100 000 vaccinated persons).
Karlstad Ø, Hovi P, Husby A, et al. SARS-CoV-2 vaccination and myocarditis in a Nordic cohort study of 23 million residents. JAMA Cardiol. 2022;7:600-12. 35442390.
2266. In persons at risk for poor vaccination response or COVID-19 exposure, tixagevimab + cilgavimab reduced COVID-19.
Levin MJ, Ustianowski A, De Wit S, et al. Intramuscular AZD7442 (tixagevimab-cilgavimab) for prevention of Covid-19. N Engl J Med. 2022;386:2188-200. 35443106.
2267. Preventing Obesity in Midlife Women: A Systematic Review for the Women's Preventive Services Initiative.
作者: Amy G Cantor.;Heidi D Nelson.;Miranda Pappas.;Chandler Atchison.
来源: Ann Intern Med. 2022年175卷9期1275-1284页
Despite high prevalence rates of obesity in the United States, no clinical guidelines exist for obesity prevention in midlife women who commonly experience weight gain.
2268. In IBS, a smartphone application for self-managing a FODMAP-lowering diet vs. otilonium bromide reduced symptoms at 8 wk.
Carbone F, Van den Houte K, Besard L, et al. Diet or medication in primary care patients with IBS: the DOMINO study-a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute. Gut. 2022. [Epub ahead of print]. 35483886.
2270. Reduced dietary sodium did not reduce clinical events in heart failure.
Ezekowitz JA, Colin-Ramirez E, Ross H, et al. Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial. Lancet. 2022;399:1391-400. 35381194.
2272. Evaluating the Performance of Centers for Disease Control and Prevention COVID-19 Community Levels as Leading Indicators of COVID-19 Mortality.
Centers for Disease Control and Prevention (CDC) defines low, medium, and high "COVID-19 community levels" to guide interventions, but associated mortality rates have not been reported.
2273. Recommendations for use of ezetimibe and/or PCSK9 inhibitors in patients with elevated LDL-C.
Hao Q, Aertgeerts B, Guyatt G, et al. PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations. BMJ. 2022;377:e069066. 35508320.
2274. In diabetes, some statins reduce non-HDL-C better than others vs. placebo.
Hodkinson A, Tsimpida D, Kontopantelis E, et al. Comparative effectiveness of statins on non-high density lipoprotein cholesterol in people with diabetes and at risk of cardiovascular disease: systematic review and network meta-analysis. BMJ. 2022;376:e067731. 35331984.
2277. Telehealth Strategies for the Delivery of Maternal Health Care : A Rapid Review.
作者: Amy G Cantor.;Rebecca M Jungbauer.;Annette M Totten.;Ellen L Tilden.;Rebecca Holmes.;Azrah Ahmed.;Jesse Wagner.;Amy C Hermesch.;Marian S McDonagh.
来源: Ann Intern Med. 2022年175卷9期1285-1297页
Telehealth strategies to supplement or replace in-person maternity care may affect maternal health outcomes.
2278. Associations of Atrial Fibrillation After Noncardiac Surgery With Stroke, Subsequent Arrhythmia, and Death : A Cohort Study.
作者: Konstantinos C Siontis.;Bernard J Gersh.;Susan A Weston.;Ruoxiang Jiang.;Véronique L Roger.;Peter A Noseworthy.;Alanna M Chamberlain.
来源: Ann Intern Med. 2022年175卷8期1065-1072页
Postoperative atrial fibrillation (AF) after noncardiac surgery confers increased risks for ischemic stroke and transient ischemic attack (TIA). How outcomes for postoperative AF after noncardiac surgery compare with those for AF occurring outside of the operative setting is unknown.
2279. Ethical Considerations in Precision Medicine and Genetic Testing in Internal Medicine Practice: A Position Paper From the American College of Physicians.
作者: Lisa Soleymani Lehmann.;Lois Snyder Sulmasy.;Wylie Burke.; .
来源: Ann Intern Med. 2022年175卷9期1322-1323页
This American College of Physicians position paper aims to inform ethical decision making for the integration of precision medicine and genetic testing into clinical care. Although the positions are primarily intended for practicing physicians, they may apply to other health care professionals and can also inform how health care systems, professional schools, and residency programs integrate genomics into educational and clinical settings. Addressing the challenges of precision medicine and genetic testing will guide ethical and responsible implementation to improve health outcomes.
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