2225. USPSTF recommends aspirin to prevent CVD in adults 40 to 59 y as an individual decision; not recommended for adults ≥60 y.
Davidson KW, Barry MJ, Mangione CM, et al. Aspirin use to prevent cardiovascular disease: US Preventive Services Task Force recommendation statement. JAMA. 2022;327:1577-84. 35471505.
2226. In type 2 diabetes, SGLT2 inhibitors reduced risk for serious hyperkalemia without increasing hypokalemia.
Neuen BL, Oshima M, Agarwal R, et al. Sodium-glucose cotransporter 2 inhibitors and risk of hyperkalemia in people with type 2 diabetes: a meta-analysis of individual participant data from randomized, controlled trials. Circulation. 2022;145:1460-70. 35394821.
2227. In moderate-to-severe asthma, as-needed albuterol-budesonide reduced severe exacerbations vs. albuterol alone.
Papi A, Chipps BE, Beasley R, et al. Albuterol-budesonide fixed-dose combination rescue inhaler for asthma. N Engl J Med. 2022;386:2071-83. 35569035.
2228. In older LTC residents, transitional care interventions vs. usual care reduce hospital readmissions.
Birtwell K, Planner C, Hodkinson A, et al. Transitional care interventions for older residents of long-term care facilities: a systematic review and meta-analysis. JAMA Netw Open. 2022;5:e2210192. 35507344.
2229. In COVID-19 acute hypoxemia, awake prone positioning vs. usual care did not reduce intubation at 30 d.
Alhazzani W, Parhar KK, Weatherald J, et al. Effect of awake prone positioning on endotracheal intubation in patients with COVID-19 and acute respiratory failure: a randomized clinical trial. JAMA. 2022;327:2104-13. 35569448.
2230. In IgA nephropathy, oral methylprednisolone reduced adverse kidney outcomes but increased adverse events.
Lv J, Wong MG, Hladunewich MA, et al. Effect of oral methylprednisolone on decline in kidney function or kidney failure in patients with IgA nephropathy: the TESTING randomized clinical trial. JAMA. 2022;327:1888-98. 35579642.
2231. In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control.
Mun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.
2232. Early Rhythm Control Therapy for Atrial Fibrillation in Low-Risk Patients : A Nationwide Propensity Score-Weighted Study.
作者: Daehoon Kim.;Pil-Sung Yang.;Seng Chan You.;Eunsun Jang.;Hee Tae Yu.;Tae-Hoon Kim.;Hui-Nam Pak.;Moon-Hyoung Lee.;Gregory Y H Lip.;Jung-Hoon Sung.;Boyoung Joung.
来源: Ann Intern Med. 2022年175卷10期1356-1365页
Rhythm control is associated with lower risk for adverse cardiovascular outcomes compared with usual care among patients recently diagnosed with atrial fibrillation (AF) with a CHA2DS2-VASc score of approximately 2 or greater in EAST-AFNET 4 (Early Treatment of Atrial Fibrillation for Stroke Prevention Trial).
2234. Maternal, Infant, and Child Health Outcomes Associated With the Special Supplemental Nutrition Program for Women, Infants, and Children : A Systematic Review.
作者: Maya Venkataramani.;S Michelle Ogunwole.;Laura E Caulfield.;Ritu Sharma.;Allen Zhang.;Susan M Gross.;Kristen M Hurley.;Jennifer L Lerman.;Eric B Bass.;Wendy L Bennett.
来源: Ann Intern Med. 2022年175卷10期1411-1422页
The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is intended to improve maternal and child health outcomes. In 2009, the WIC food package changed to better align with national nutrition recommendations.
2236. In older adults discharged from hospital, home-based exercise programs improve some outcomes.
Lin I, Glinsky J, Dean C, et al. Effectiveness of home-based exercise for improving physical activity, quality of life and function in older adults after hospitalisation: a systematic review and meta-analysis. Clin Rehabil. 2022;36:1170-85. 35522200.
2237. In frail older adults with sarcopenia, a multicomponent intervention vs. education reduced mobility disability at 26 mo.
Bernabei R, Landi F, Calvani R, et al. Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project). BMJ. 2022;377:e068788. 35545258.
2239. In patients with CHD, a Mediterranean vs. low-fat diet reduced major CV events at 7 y.
Delgado-Lista J, Alcala-Diaz JF, Torres-Peña JD, et al. Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial. Lancet. 2022;399:1876-85. 35525255.
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