207. Sudden Right Lower Limb Paralysis: An Uncommon Presentation of Type A Aortic Dissection.
Acute aortic dissection is a rare and life-threatening emergency, with fatal outcomes often resulting from delayed or missed diagnoses. Type A aortic dissection, which typically presents with acute chest pain radiating to the back, is the most common cause of death associated with aortic lesions and requires urgent surgical intervention. We present an unusual case of type A aortic dissection that manifested solely with sudden paralysis and tingling of the right lower limb, without chest or back pain. Despite timely diagnosis in the emergency department, emergency surgical intervention failed to save the patient's life.
214. Low-Tidal-Volume Ventilation and Mortality in Patients With Acute Brain Injury: A Secondary Analysis of an International Observational Study.
作者: Julian F Daza.;Doulia M Hamad.;Martin Urner.;Kuan Liu.;Sarah Wahlster.;Chiara Robba.;Robert D Stevens.;Victoria A McCredie.;Raphael Cinotti.;Shaurya Taran.; .; .; .; .; .; .
来源: Chest. 2025年168卷5期1141-1151页
Low-tidal-volume ventilation (LTVV) improves outcomes in critically ill patients, but its impact in patients with acute brain injuries (ABIs) is less certain.
215. The Influence of Hospital Policies on Clinicians' Decisions to Withhold or Withdraw Life-Sustaining Treatment.
作者: Gina M Piscitello.;Edlyn Lopez Wolwowicz.;Michael T Huber.;Kelly C Vranas.;Donald R Sullivan.;Katrina E Hauschildt.;Patrick G Lyons.
来源: Chest. 2025年
There is considerable variation in clinicians' approaches to decisions to withhold or withdraw life-sustaining treatment (LST) across US hospitals. These differences are not explained by patient preferences alone and are likely influenced by other factors (eg, hospital policies, hospital culture, state laws, medical society guidelines).
216. The Impact of the Unknown: Patient Experiences With Uncertainty in Sarcoidosis.
作者: Kristen R Mathias.;Michelle N Eakin.;Katrina E Hauschildt.;Edward S Chen.;Nisha A Gilotra.;Nancy W Lin.;Catherine A Bonham.;Michelle Sharp.
来源: Chest. 2025年
Individuals with sarcoidosis face many sources of illness uncertainty, including diagnostic delays, unpredictable therapeutic efficacy and toxicity, and disease-associated morbidity and mortality. Patient perspectives on illness uncertainty in sarcoidosis have not been evaluated critically and offer an opportunity for providers to contextualize and prioritize gaps in care and patient support.
217. Beryllium Lymphocyte Proliferation Test: Differential Diagnosis of Sarcoidosis and Chronic Beryllium Disease.
作者: Louis Jouanjan.;Charlott Terschluse.;Gernot Zissel.;Prerana Agarwal.;Emil Wachenfeld.;Caroline Quartucci.;Daniel Soriano.;Joachim Müller-Quernheim.;Daiana Stolz.;Björn C Frye.
来源: Chest. 2025年
Chronic beryllium disease (CBD) is considered a phenocopy of sarcoidosis, generally caused by occupational exposure to beryllium. Its diagnosis relies on the demonstration of beryllium sensitization by the beryllium lymphocyte proliferation test (BeLPT).
218. Segmentectomy vs Lobectomy for Patients With 2- to 3-cm Non-Small Cell Lung Cancer.
作者: Camille A Mathey-Andrews.;Alexandra L Potter.;Deepti Srinivasan.;Priyanka Senthil.;Hiba Elkhatib.;Danny Wang.;Arvind Kumar.;Michael Lanuti.;Lana Schumacher.;Chi-Fu Jeffrey Yang.
来源: Chest. 2025年
Two studies recently demonstrated the noninferiority of sublobar resection to lobectomy in patients with T1a-bN0M0 non-small cell lung cancer (NSCLC). However, whether segmentectomy is associated with similar oncologic outcomes to lobectomy for patients with node-negative T1c tumors (ie, those 2-3 cm) remains unknown.
219. Incidence of Discordant Pleural Fluid Exudates and Diagnostic Patterns: A Retrospective Cohort Study.
作者: Dinesh N Addala.;Rachel Mercer.;Anand Sundaralingam.;Beenish Iqbal.;Alguili Elsheikh.;Eihab O Bedawi.;John Wrightson.;Robert J Hallifax.;Najib M Rahman.
来源: Chest. 2025年
Light's criteria use pleural fluid protein and lactate dehydrogenase (LDH) to differentiate pleural effusions as exudative or transudative. In a subset of exudative pleural effusions, discordance occurs between LDH and protein (ie, protein high, LDH low, or vice versa).
220. Airway Mucus Plugging in Chronic Bronchitis and the Impact of Bronchial Rheoplasty.
作者: William S Krimsky.;Joseph G Mammarappallil.;Victor Kim.;Brett Bannan.;Jean-Paul Charbonnier.;Beryl A Hatton.;Frank C Sciurba.
来源: Chest. 2025年
Chronic bronchitis (CB) is characterized by excessive airway mucus production. Mucus plugs occluding the airway are common in CB, are associated with increased all-cause mortality, and can be identified on CT imaging.
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