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2. Admission Eosinophil Count Is Associated with Hospital Resource Utilization in Community-Acquired Pneumonia: A Prospective Multicenter Study.
作者: Barbara Christine Weckler.;Qiong Wu.;Wilhelm Bertrams.;Max Kutzinski.;Rieke Reiter.;Saeed A Khan.;Peter Ahnert.;Norbert Suttorp.;Martin Witzenrath.;Christian Wildberg.;Mathias W Pletz.;Jan Rupp.;Ulrich M Zissler.;Timm Greulich.;Thomas Brenner.;Peter Alter.;Gernot Rohde.;Claus Franz Vogelmeier.;Andreas Mayr.;Bernd Schmeck.
来源: Chest. 2026年
Eosinopenia has been associated with adverse outcomes in community-acquired pneumonia (CAP). However, its relationship with hospital resource utilization remains unclear.
3. Effects of a sea level stay on pulmonary hemodynamics in patients with pulmonary arterial hypertension living in Quito near 2850m.
作者: Silvia Ulrich.;Julian Müller.;Michael Furian.;Stéphanie Saxer.;Simon R Schneider.;Joel Herzig.;Meret Bauer.;Mirjam Schmucki.;Diego Saragoni.;Laura Mayer.;Esther I Schwarz.;Elizabeth Cajamarca.;Rodrigo Hoyos.;Mona Lichtblau.
来源: Chest. 2026年
Amongst the >80 Mio people living >2500m are patients with pulmonary arterial hypertension (PAH).
4. Early Trends After Safety Net Policy Introduction for Kidney After Lung Transplantation.
作者: Prasanth Balasubramanian.;Napat Leeaphorn.;Kristopher P Croome.;Pablo Moreno Franco.;Aditya Khanijo.;Remzi Bag.;Maher A Baz.;Narula Tathagat.;Alvarez G Francisco.;Dana K Perry.;C Burcin Taner.;Hani M Wadei.;Tambi Jarmi.;Devang Sanghavi.;Mathew Thomas.;Ian A Makey.;John Haney.;Sadia Z Shah.
来源: Chest. 2026年
The safety-net policy for kidney-after-lung transplants (KALT), implemented in the U.S. on 6/29/2023, allows Lung Transplant (LT) candidates with acute kidney injury (AKI), with or without underlying chronic kidney disease (CKD), to undergo LT alone with the potential for renal recovery. This may decrease the need to list for simultaneous lung-kidney transplant (SLKT).
5. The impact of disease severity and symptoms on anxiety and depression in individuals with idiopathic pulmonary fibrosis.
作者: Zhe Wu.;Karen Moor.;Marlies Wijsenbeek.;Christina Schlecker.;Gerrit Weimann.;Toby M Maher.;Philip L Molyneaux.
来源: Chest. 2026年
Idiopathic pulmonary fibrosis (IPF) is a debilitating, life-limiting fibrotic lung disease. Symptoms including breathlessness, cough, and fatigue, together with disease severity, contribute to psychological burden, yet the relationship between these factors and anxiety and depression remains unclear.
6. Suggested novel risk factors for Swimming-Induced Pulmonary Edema - asthma and limited open water swimming experience.
作者: Linda Kristiansson.;Claudia Seiler.;Annika Braman Eriksson.;Josefin Sundh.;Maria Hårdstedt.
来源: Chest. 2026年
Swimming-induced pulmonary edema (SIPE) has gained increasing attention in recent years. However, risk factors for SIPE remain incompletely understood, and existing data are primarily based on small-scale studies.
7. A Randomized, Placebo-Controlled, Double-Blind, Crossover Trial of Inhaled Nitric Oxide in Patients With Mild-to-Severe COPD.
作者: Sophie É Collins.;Miranda Kirby.;Benjamin M Smith.;Zahrah H Rampuri.;Desi P Fuhr.;Samira Rowland.;Andrew R Brotto.;Rhonda J Rosychuk.;Stephanie Thompson.;Jason Weatherald.;Sean van Diepen.;Michael K Stickland.; .
来源: Chest. 2026年
Patients with advanced COPD have pulmonary vascular dysfunction and destruction; thus, it is unclear whether they are responsive to selective pulmonary vasodilators.
8. Efficacy and Safety of Ensifentrine in Chinese Patients with Chronic Obstructive Pulmonary Disease: The ENHANCE-CHINA Randomized Clinical Trial.
作者: Yumin Zhou.;Charlie Chen.;Zihui Wang.;Fan Wu.;Dongbo Tian.;Zuke Xiao.;Jie Cao.;Feng Xu.;Junzhen Gao.;Juan Chen.;Liping Peng.;Yuanrong Dai.;Limin Dong.;Yi Hu.;Ting Yang.;Chuntao Liu.;Limin Wang.;Xiao Liu.;Tiebo Yang.;Guoru Yang.;Dan Zhu.;Zonghui Wei.;Wei Gu.;Pixin Ran.;Nanshan Zhong.; .
来源: Chest. 2026年
Ensifentrine, a novel phosphodiesterase 3/4 inhibitor, significantly improved lung function and reduced chronic obstructive pulmonary disease (COPD) exacerbations in previous trials in Western populations. However, efficacy and safety data on its use in participants with COPD in China remain limited.
9. Cone Beam Computed Tomography-Guided Bronchoscopy versus Computed Tomography-Guided Transthoracic Needle Biopsy for Peripheral Pulmonary Lesion Diagnosis.
作者: Pranjal Patel.;David E Ost.;Brian Shaller.;Jiwoon Chang.;Aishwarya Yenepalli.;Hee Jae Choi.;Dwayne Free.;Cyra-Yoonsun Kang.;Eric Sumner.;Carrie Cao.;Harmeet Bedi.
来源: Chest. 2026年
The identification of peripheral pulmonary lesions (PPLs) has increased significantly, either incidentally or through lung cancer screening, necessitating more biopsies to differentiate between malignant and benign etiologies. Cone beam computed tomography-guided bronchoscopic biopsy (CBCT-GB) and computed tomography-guided transthoracic needle biopsy (CT-TTNB) are commonly used for these biopsies, but their comparative diagnostic abilities have not been studied.
10. The Economic Consequence of Increased Healthcare Resource Utilization in Maryland Associated with a Major Wildfire Smoke Event.
作者: Zafar Zafari.;Mary E Maldarelli.;Clayton H Brown.;Madhurika Situt.;Colleen Reilly.;Rozalina McCoy.;Martha Jurczak.;Amir Sapkota.;Katarina Zeder.;Warren D'Souza.;Bradley A Maron.
来源: Chest. 2026年
Transcontinental wildfire smoke migration originating from remote areas resulted in consecutive days of high concentrations of particulate matter (PM2.5) in Maryland in June 2023.
11. Timely antibiotics and fluid resuscitation are associated with increased discharge to home after sepsis.
作者: Hallie C Prescott.;Julien Weinstein.;Sarah Seelye.;Jason D Buxbaum.;Steven J Bernstein.;Megan Cahill.;Megan Heath.;Lama Hsaiky.;Jennifer K Horowitz.;Namita Jayaprakash.;Anurag N Malani.;Elizabeth McLaughlin.;Lakshmi Swaminathan.;Patricia J Posa.;Scott A Flanders.;Andrew M Ryan.
来源: Chest. 2026年
Sepsis is a devastating condition with frequent discharge to non-home settings such as skilled nursing facilities. Bundled payment incentive programs targeting sepsis have tried to encourage lower spending by avoiding discharge to institutional post-acute care.
12. Integrating deep learning of low-dose computed tomography with clinical data for lung cancer risk prediction.
作者: Renzo Phellan Aro.;Stephen Lam.;Matthew T Warkentin.;Geoffrey Liu.;Brenda Diergaarde.;David O Wilson.;Jian-Min Yuan.;Hamad Al-Sawaihey.;Kiera Murison.;Elham Khodayari Moez.;Yonathan Brhane.;Rafael Meza.;Renelle Myers.;Rayjean J Hung.
来源: Chest. 2026年
Low-dose computed tomography (LDCT) screening reduces lung cancer mortality, the leading cause of cancer deaths globally. Segmentation-free deep learning (DL) models such as Sybil can improve screening efficiency but require extensive validation and possible improvement.
16. Antimicrobial Treatment of Mild Mycobacterium avium Complex-Pulmonary Disease Predicted to Increase Survival and Quality Adjusted Life Years: A Microsimulation Decision Analysis Model.
作者: Omri A Arbiv.;Gemma Postill.;Yunjoo Im.;Byung Woo Jhun.;Petros Pechlivanoglou.;Sarah K Brode.;Ahmed M Bayoumi.;Theodore K Marras.
来源: Chest. 2026年
Mycobacterium avium complex-pulmonary disease (MAC-PD) can lead to chronic lung disease, which can necessitate intensive antimicrobial therapy. In patients with mild MAC-PD, there is uncertainty in whether guideline-based antimicrobial treatment should be used as compared to watchful waiting.
17. OSA is associated with enhanced coronary collateral circulation and reduced myocardial injury during acute coronary syndromes.
作者: Krish Dodani.;Albina Aldomà.;Adriano Targa.;Manuel Sánchez-de-la-Torre.;Alicia Sánchez-de-la-Torre.;Lucía Pinilla.;Jorge Abad.;Olga Mínguez.;Lydia Pascual.;Dolores Martínez.;Rafaela Vaca.;Ivan Juez-Garcia.;Ferran Barbé.;Ivan Benitez.
来源: Chest. 2026年
Some evidence suggests that obstructive sleep apnea (OSA) may attenuate myocardial injury and reduce infarct severity during acute coronary syndromes (ACS), potentially through stimulation of coronary collateral circulation (CCC). However, the relationship between OSA and collateral development, and their combined impact on ACS event severity, remains unclear.
18. Clinical and cost-effectiveness of pulmonary rehabilitation for people with post-tuberculosis lung disease in Uganda: a randomised controlled trial.
作者: Winceslaus Katagira.;Mark W Orme.;Richard Kasiita.;Jesse A Matheson.;Matthew Richardson.;Andy Barton.;Jalia Nanyonga.;Michael C Steiner.;Bruce Kirenga.;Sally J Singh.
来源: Chest. 2026年
Background Post-tuberculosis lung disease (PTLD) causes significant disability in TB survivors. Pulmonary rehabilitation (PR) may offer effective disease management but lacks high-quality evidence in this underrepresented population.
19. Win Ratio Analysis to Clarify Clinical Benefits: A Post Hoc Analysis of Phase 3 BOREAS and NOTUS.
作者: Sanjay Ramakrishnan.;Nayia Petousi.;Jessica Bon.;Ian D Pavord.;Surya P Bhatt.;Klaus F Rabe.;Wenying Deng.;Changming Xia.;Jigna Heble.;Mena Soliman.;Simon Couillard.
来源: Chest. 2026年 20. Evaluating the Association Between Patient Priorities and ICU Care Delivery in Adults Receiving Mechanical Ventilation.
作者: Kara A Donovan.;Madison Polley.;Geralyn Palmer.;Bret M Hanlon.;Lily N Stalter.;Helen K Donnelly.;Richard G Wunderink.;Catherine A Gao.;Jacqueline M Kruser.; .
来源: Chest. 2026年
Understanding how intensive care unit (ICU) treatments align with a patient's priorities is crucial to evaluating and improving critical care. Yet, measuring this alignment is challenging because patient priorities evolve over time and are not systematically documented in electronic health records (EHR).
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