当前位置: 首页 >> 检索结果
1324. Responding to Reviewers and Editors About Statistical Significance Testing.
作者: David A Savitz.;Lauren A Wise.;Julia C Bond.;Elizabeth E Hatch.;Collette N Ncube.;Amelia K Wesselink.;Mary D Willis.;Jennifer J Yland.;Kenneth J Rothman.
来源: Ann Intern Med. 2024年177卷3期385-386页 1325. Autoimmune Disorders Associated With Surgical Remission of Cushing's Disease : A Cohort Study.
作者: Dennis Delasi Nyanyo.;Masaaki Mikamoto.;Francesca Galbiati.;Ilan Remba-Shapiro.;Kevin Bode.;Sara Schoenfeld.;Pamela S Jones.;Brooke Swearingen.;Lisa B Nachtigall.
来源: Ann Intern Med. 2024年177卷3期315-323页
Glucocorticoids suppress inflammation. Autoimmune disease may occur after remission of Cushing's disease (CD). However, the development of autoimmune disease in this context is not well described.
1327. How Would You Prevent Subsequent Strokes in This Patient? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
作者: Zahir Kanjee.;Jennifer L Dearborn-Tomazos.;Sandeep Kumar.;Eileen E Reynolds.
来源: Ann Intern Med. 2024年177卷2期238-245页
Stroke is a major cause of morbidity, mortality, and disability. The American Heart Association/American Stroke Association recently published updated guidelines on secondary stroke prevention. In these rounds, 2 vascular neurologists use the case of Mr. S, a 75-year-old man with a history of 2 strokes, to discuss and debate questions in the guideline concerning intensity of atrial fibrillation monitoring in embolic stroke of undetermined source, diagnosis and management of moderate symptomatic carotid stenosis, and therapeutic strategies for recurrent embolic stroke of undetermined source in the setting of guideline-concordant therapy.
1328. Surgery, Needle Fasciotomy, or Collagenase Injection for Dupuytren Contracture : A Randomized Controlled Trial.
作者: Mikko Petteri Räisänen.;Olli V Leppänen.;Janne Soikkeli.;Aleksi Reito.;Antti Malmivaara.;Rachelle Buchbinder.;Hannu Kautiainen.;Antti Kaivorinne.;Susanna Stjernberg-Salmela.;Minna Lappalainen.;Toni Luokkala.;Annele Pönkkö.;Hanna-Stiina Taskinen.;Markus Pääkkönen.;Kati Jaatinen.;Joona Juurakko.;Venla-Linnea Karjalainen.;Teemu Karjalainen.
来源: Ann Intern Med. 2024年177卷3期280-290页
Surgery, needle fasciotomy, and collagenase injection are used to treat Dupuytren contracture. The treatment decision requires balancing initial morbidity and costs of surgery against its potential long-term benefits over needle fasciotomy and collagenase.
1329. Immune-Related Adverse Events of Immune Checkpoint Inhibitors.
Immune-related adverse events (irAEs) are toxicities that arise after the administration of monoclonal antibodies targeting immune checkpoints (immune checkpoint inhibitors [ICIs]) in patients with cancer. They can occur at any time after initiation of ICI treatment, with a broad clinical phenotype that can be organ-specific or systemic. Although most irAEs manifest as mild to moderate signs and symptoms, severe forms of irAEs can lead to irreversible organ failure and have acute life-threatening presentations. Treatment should be tailored to the specific organ involved and the severity. Glucocorticoids are the first-line treatment for most irAEs, with immunosuppressants and biologics mainly used as second-line treatments.
1331. Trends in Psychological Distress and Outpatient Mental Health Care of Adults During the COVID-19 Era.
作者: Mark Olfson.;Chandler McClellan.;Samuel H Zuvekas.;Melanie Wall.;Carlos Blanco.
来源: Ann Intern Med. 2024年177卷3期353-362页
In addition to the physical disease burden of the COVID-19 pandemic, concern exists over its adverse mental health effects.
1332. AABB recommends restrictive RBC transfusions for hospitalized adults and children.
Carson JL, Stanworth SJ, Guyatt G, et al. Red blood cell transfusion: 2023 AABB international guidelines. JAMA. 2023;330:1892-1902. 37824153.
1333. In T2DM with obesity, time-restricted eating increased weight loss and reduced HbA1c level at 6 mo.
Pavlou V, Cienfuegos S, Lin S, et al. Effect of time-restricted eating on weight loss in adults with type 2 diabetes: a randomized clinical trial. JAMA Netw Open. 2023;6:e2339337. 37889487.
1334. In nursing homes, universal decolonization vs. routine care reduced transfers to hospital for infection.
Miller LG, McKinnell JA, Singh RD, et al. Decolonization in nursing homes to prevent infection and hospitalization. N Engl J Med. 2023;389:1766-1777. 37815935.
1335. In acute hypoxemic respiratory failure, noninvasive oxygenation methods may reduce death vs. standard oxygen therapy.
Pitre T, Zeraatkar D, Kachkovski GV, et al. Noninvasive oxygenation strategies in adult patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis. Chest. 2023;164:913-928. 37085046.
1336. In patients with OSA and CVD, CPAP did not reduce major adverse cardiac and cerebrovascular events.
Sanchez-de-la-Torre M, Gracia-Lavedan E, Benitez ID, et al. Adherence to CPAP treatment and the risk of recurrent cardiovascular events: a meta-analysis. JAMA. 2023;330:1255-1265. 37787793.
1338. In persons aged ≥45 y, the mt-sRNA test had 94% sensitivity for colorectal cancer and 46% for advanced adenomas.
Barnell EK, Wurtzler EM, La Rocca J, et al. Multitarget stool RNA test for colorectal cancer screening. JAMA. 2023;330:1760-1768. 37870871.
1339. In women aged 45 to 75 y, opt-out vs. opt-in breast cancer screening outreach did not increase mammography rates.
Marcotte LM, Deeds S, Wheat C, et al. Automated opt-out vs opt-in patient outreach strategies for breast cancer screening: a randomized clinical trial. JAMA Intern Med. 2023;183:1187-1194. 37695621.
1340. In hypertension, with or without orthostatic hypotension, more- vs. less-intensive BP therapy improves clinical outcomes.
Juraschek SP, Hu JR, Cluett JL, et al. Orthostatic hypotension, hypertension treatment, and cardiovascular disease: an individual participant meta-analysis. JAMA. 2023;330:1459-1471. 37847274.
|